2xkv
From Proteopedia
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| - | [[ | + | ==Atomic Model of the SRP-FtsY Early Conformation== |
| + | <StructureSection load='2xkv' size='340' side='right' caption='[[2xkv]], [[Resolution|resolution]] 13.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2xkv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ], [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XKV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XKV FirstGlance]. <br> | ||
| + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j28|2j28]], [[2j7p|2j7p]], [[1jpj|1jpj]], [[1ng1|1ng1]], [[2cnw|2cnw]], [[2c03|2c03]], [[1dul|1dul]], [[2ng1|2ng1]], [[1ls1|1ls1]], [[1o87|1o87]], [[1ry1|1ry1]], [[1jpn|1jpn]], [[2j45|2j45]], [[2j46|2j46]], [[1rj9|1rj9]], [[1ffh|1ffh]], [[1hq1|1hq1]], [[2ffh|2ffh]], [[2c04|2c04]], [[2iyl|2iyl]], [[1okk|1okk]], [[2iy3|2iy3]], [[3ng1|3ng1]]</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Signal-recognition-particle_GTPase Signal-recognition-particle GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.4 3.6.5.4] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xkv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xkv RCSB], [http://www.ebi.ac.uk/pdbsum/2xkv PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | We report the 'early' conformation of the Escherichia coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome, as determined by cryo-EM. FtsY binds to the tetraloop of the SRP RNA, whereas the NG domains of the SRP protein and FtsY interact weakly in this conformation. Our results suggest that optimal positioning of the SRP RNA tetraloop and the Ffh NG domain leads to FtsY recruitment. | ||
| - | + | Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor.,Estrozi LF, Boehringer D, Shan SO, Ban N, Schaffitzel C Nat Struct Mol Biol. 2011 Jan;18(1):88-90. Epub 2010 Dec 12. PMID:21151118<ref>PMID:21151118</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
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==See Also== | ==See Also== | ||
*[[Signal recognition particle protein|Signal recognition particle protein]] | *[[Signal recognition particle protein|Signal recognition particle protein]] | ||
| - | + | *[[Signal recognition particle receptor|Signal recognition particle receptor]] | |
| - | == | + | == References == |
| - | < | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus coli migula 1895]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Signal-recognition-particle GTPase]] | [[Category: Signal-recognition-particle GTPase]] | ||
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[[Category: Estrozi, L F.]] | [[Category: Estrozi, L F.]] | ||
[[Category: Schaffitzel, C.]] | [[Category: Schaffitzel, C.]] | ||
| - | [[Category: Shan, S | + | [[Category: Shan, S o.]] |
[[Category: Protein transport]] | [[Category: Protein transport]] | ||
Revision as of 13:10, 22 October 2014
Atomic Model of the SRP-FtsY Early Conformation
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