2mbf

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<StructureSection load='2mbf' size='340' side='right' caption='[[2mbf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mbf' size='340' side='right' caption='[[2mbf]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mbf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bruma Bruma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MBF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mbf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MBF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MBF FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Bm1_50095 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6279 BRUMA])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mbf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mbf RCSB], [http://www.ebi.ac.uk/pdbsum/2mbf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mbf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mbf RCSB], [http://www.ebi.ac.uk/pdbsum/2mbf PDBsum]</span></td></tr>
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</table>
</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Brugia malayi is a parasitic nematode that causes lymphatic filariasis in humans. Here the solution structure of the forkhead DNA binding domain of Brugia malayi DAF-16a, a putative ortholog of Caenorhabditis elegans DAF-16, is reported. It is believed to be the first structure of a forkhead or winged helix domain from an invertebrate. C. elegans DAF-16 is involved in the insulin/IGF-I signaling pathway and helps control metabolism, longevity, and development. Conservation of sequence and structure with human FOXO proteins suggests that B. malayi DAF-16a is a member of the FOXO family of forkhead proteins. Proteins 2014. (c) 2014 Wiley Periodicals, Inc.
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The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a.,Casper SK, Schoeller SJ, Zgoba DM, Phillips AJ, Morien TJ, Chaffee GR, Sackett PC, Peterson FC, Crossgrove K, Veldkamp CT Proteins. 2014 Oct 9. doi: 10.1002/prot.24701. PMID:25297652<ref>PMID:25297652</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bruma]]
 
[[Category: Casper, S K.]]
[[Category: Casper, S K.]]
[[Category: Peterson, F C.]]
[[Category: Peterson, F C.]]

Revision as of 09:03, 29 October 2014

Solution structure of the forkhead domain of Brugia malayi DAF-16a

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