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2xyr

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<StructureSection load='2xyr' size='340' side='right' caption='[[2xyr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2xyr' size='340' side='right' caption='[[2xyr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xyr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYR OCA]. <br>
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<table><tr><td colspan='2'>[[2xyr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XYR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d2d|2d2d]], [[2ahm|2ahm]], [[1p9t|1p9t]], [[2xyv|2xyv]], [[1uk3|1uk3]], [[1wof|1wof]], [[2a5i|2a5i]], [[2v6n|2v6n]], [[2amd|2amd]], [[2acf|2acf]], [[2xyq|2xyq]], [[2bx4|2bx4]], [[1uk4|1uk4]], [[1z1i|1z1i]], [[1o5s|1o5s]], [[2c3s|2c3s]], [[2a5k|2a5k]], [[1sxf|1sxf]], [[1uk2|1uk2]], [[1uj1|1uj1]], [[1pa5|1pa5]], [[2bx3|2bx3]], [[2amq|2amq]], [[1puk|1puk]], [[1uw7|1uw7]], [[1p76|1p76]], [[1q1x|1q1x]], [[1ysy|1ysy]], [[2a5a|2a5a]], [[1z1j|1z1j]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d2d|2d2d]], [[2ahm|2ahm]], [[1p9t|1p9t]], [[2xyv|2xyv]], [[1uk3|1uk3]], [[1wof|1wof]], [[2a5i|2a5i]], [[2v6n|2v6n]], [[2amd|2amd]], [[2acf|2acf]], [[2xyq|2xyq]], [[2bx4|2bx4]], [[1uk4|1uk4]], [[1z1i|1z1i]], [[1o5s|1o5s]], [[2c3s|2c3s]], [[2a5k|2a5k]], [[1sxf|1sxf]], [[1uk2|1uk2]], [[1uj1|1uj1]], [[1pa5|1pa5]], [[2bx3|2bx3]], [[2amq|2amq]], [[1puk|1puk]], [[1uw7|1uw7]], [[1p76|1p76]], [[1q1x|1q1x]], [[1ysy|1ysy]], [[2a5a|2a5a]], [[1z1j|1z1j]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xyr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xyr RCSB], [http://www.ebi.ac.uk/pdbsum/2xyr PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xyr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xyr RCSB], [http://www.ebi.ac.uk/pdbsum/2xyr PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.,Decroly E, Debarnot C, Ferron F, Bouvet M, Coutard B, Imbert I, Gluais L, Papageorgiou N, Sharff A, Bricogne G, Ortiz-Lombardia M, Lescar J, Canard B PLoS Pathog. 2011 May;7(5):e1002059. Epub 2011 May 26. PMID:21637813<ref>PMID:21637813</ref>
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.,Decroly E, Debarnot C, Ferron F, Bouvet M, Coutard B, Imbert I, Gluais L, Papageorgiou N, Sharff A, Bricogne G, Ortiz-Lombardia M, Lescar J, Canard B PLoS Pathog. 2011 May;7(5):e1002059. Epub 2011 May 26. PMID:21637813<ref>PMID:21637813</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Ortiz-Lombardia, M.]]
[[Category: Ortiz-Lombardia, M.]]
[[Category: Papageorgiou, N.]]
[[Category: Papageorgiou, N.]]
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[[Category: Rossman fold]]
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[[Category: Rossmann fold]]
[[Category: Transferase-viral protein complex]]
[[Category: Transferase-viral protein complex]]

Revision as of 14:07, 3 November 2014

CRYSTAL STRUCTURE OF THE NSP16 NSP10 SARS CORONAVIRUS COMPLEX

2xyr, resolution 2.50Å

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