6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

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== Structural highlights ==
== Structural highlights ==
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</StructureSection>
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==3D structures of HPPK==
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==3D structures of HPPK (Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}})==
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{{#tree:id=OrganizedByTopic|openlevels=0|
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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*HPPK
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===HPPK===
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**[[1hka]], [[1eq0]] – EcHPPK – ''Escherichia coli''<br />
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**[[1g4c]], [[1im6]], [[1kbr]], [[1rtz]], [[1tmj]], [[3hcx]], [[3hsd]], [[3hsj]], [[3hsz]], [[3ili]], [[3ill]], [[3kue]], [[3kug]] – EcHPPK (mutant) <br />
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**[[2f63]], [[2f65]] – EcHPPK - NMR <br />
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[[1hka]], [[1eq0]] – EcHPPK – ''Escherichia coli''<br />
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*HPPK binary complex
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[[1g4c]], [[1im6]], [[1kbr]], [[1rtz]], [[1tmj]], [[3hcx]], [[3hsd]], [[3hsj]], [[3hsz]], [[3ili]], [[3ill]], [[3kue]], [[3kug]] – EcHPPK (mutant) <br />
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[[2f63]], [[2f65]] – EcHPPK - NMR <br />
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===HPPK binary complex===
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**[[1cbk]] – HPPK + dihydro-dimethyl-6-hydroxypterin – ''Haemophilus influenza''<br />
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**[[1eqm]] – EcHPPK + ADP <br />
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**[[1ex8]] – EcHPPK + adenosine-tetraphosphate-methyl-dihydropterin <br />
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**[[1rb0]] – EcHPPK + 6-hydroxymethylpterin-diphosphate <br />
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**[[3hd1]], [[3hsg]], [[3ht0]], [[3ilj]], [[3kuh]] – EcHPPK (mutant) + methyleneadenosine-triphosphate <br />
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**[[3ud5]], [[3ude]], [[3udv]], [[4f7v]] – EcHPPK + inhibitor <br />
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**[[3qbc]] – HPPK + inhibitor – ''Staphylococcus aureus''<br />
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[[1cbk]] – HPPK + dihydro-dimethyl-6-hydroxypterin – ''Haemophilus influenza''<br />
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*HPPK ternary complex
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[[1eqm]] – EcHPPK + ADP <br />
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[[1ex8]] – EcHPPK + adenosine-tetraphosphate-methyl-dihydropterin <br />
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[[1rb0]] – EcHPPK + 6-hydroxymethylpterin-diphosphate <br />
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[[3hd1]], [[3hsg]], [[3ht0]], [[3ilj]], [[3kuh]] – EcHPPK (mutant) + methyleneadenosine-triphosphate <br />
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[[3ud5]], [[3ude]], [[3udv]], [[4f7v]] – EcHPPK + inhibitor <br />
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[[3qbc]] – HPPK + inhibitor – ''Staphylococcus aureus''<br />
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===HPPK ternary complex===
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[[1ru2]], [[1tmm]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + 6-hydroxymethylpterin <br />
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[[1dy3]] – EcHPPK (mutant) + ATP + pteridine derivative <br />
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[[3ip0]] – EcHPPK + methyleneadenosine-triphosphate + pteridine derivative <br />
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[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pteridine derivative <br />
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[[3hd2]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pterine <br />
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[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + methyleneadenosine-triphosphate + inhibitor <br />
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[[1rao]] – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate <br />
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[[2qx0]] – HPPK + methyleneadenosine-triphosphate + pteridine derivative – ''Yersinia pestis''<br />
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**[[1ru2]], [[1tmm]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + 6-hydroxymethylpterin <br />
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**[[1dy3]] – EcHPPK (mutant) + ATP + pteridine derivative <br />
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**[[3ip0]] – EcHPPK + methyleneadenosine-triphosphate + pteridine derivative <br />
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**[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pteridine derivative <br />
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**[[3hd2]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pterine <br />
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**[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + methyleneadenosine-triphosphate + inhibitor <br />
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**[[1rao]] – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate <br />
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**[[2qx0]] – HPPK + methyleneadenosine-triphosphate + pteridine derivative – ''Yersinia pestis''<br />
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}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:21, 11 November 2014

Structure of E. coli HPPK complex with inhibitor (PDB code 3udv).

Drag the structure with the mouse to rotate

3D structures of HPPK (Updated on 11-November-2014)

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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