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6-phosphogluconate dehydrogenase

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'''6-phosphogluconate dehydrogenase''' (6PDH) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.
'''6-phosphogluconate dehydrogenase''' (6PDH) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.
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==3D structures of 6-phosphogluconate dehydrogenase==
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</StructureSection>
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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==3D structures of 6-phosphogluconate dehydrogenase (Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}})==
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===6PDH===
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*6PDH
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[[2pgd]] - s6PDH – sheep<BR />
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**[[2pgd]] - s6PDH – sheep<BR />
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[[1pgj]] - 6PDH – ''Trypanosoma brucei''<BR />
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**[[1pgj]] - 6PDH – ''Trypanosoma brucei''<BR />
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[[2p4q]] - 6PDH – yeast<BR />
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**[[2p4q]] - 6PDH – yeast<BR />
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[[2zyg]] - 6PDH (mutant) – ''Klebsiella pneumonia''<BR />
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**[[2zyg]] - 6PDH (mutant) – ''Klebsiella pneumonia''<BR />
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[[4e21]] - Gm6PDH – ''Geobacter metallireducens''
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**[[4e21]] - Gm6PDH – ''Geobacter metallireducens''
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[[4gbj]] – Df6PDH – ''Dyadobacter fermentans''<br />
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**[[4gbj]] – Df6PDH – ''Dyadobacter fermentans''<br />
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[[4gwg]] - h6PDH – human<br />
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**[[4gwg]] - h6PDH – human<br />
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===6PDH binary complex===
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*6PDH binary complex
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[[1pgn]] – s6PDH + Br-NADP<BR />
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**[[1pgn]] – s6PDH + Br-NADP<BR />
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[[1pgo]] - s6PDH + NADP<BR />
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**[[1pgo]] - s6PDH + NADP<BR />
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[[1pgp]] - s6PDH + 6PG<BR />
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**[[1pgp]] - s6PDH + 6PG<BR />
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[[1pgq]] - s6PDH + AMP<BR />
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**[[1pgq]] - s6PDH + AMP<BR />
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[[2jkv]] - h6PDH + NADP <BR />
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**[[2jkv]] - h6PDH + NADP <BR />
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[[4gwk]] - h6PDH + 3PG<br />
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**[[4gwk]] - h6PDH + 3PG<br />
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[[2zya]] - Ec6PDH (mutant) + 6PG – ''Escherichia coli''<BR />
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**[[2zya]] - Ec6PDH (mutant) + 6PG – ''Escherichia coli''<BR />
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[[2w8z]], [[2w90]] - 6PDH + 6PG – ''Geobacillus stearothermophilus''<BR />
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**[[2w8z]], [[2w90]] - 6PDH + 6PG – ''Geobacillus stearothermophilus''<BR />
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[[2iyo]] - Ll6PDH + 6PG – ''Lactococcus lactis''<BR />
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**[[2iyo]] - Ll6PDH + 6PG – ''Lactococcus lactis''<BR />
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[[2zyd]] - Ec6PDH (mutant) + glucose
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**[[2zyd]] - Ec6PDH (mutant) + glucose
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===6PDH ternary complex===
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*6PDH ternary complex
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[[2iz1]] - Ll6PDH + inhibitor + ADP <BR />
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**[[2iz1]] - Ll6PDH + inhibitor + ADP <BR />
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[[3fwn]] - Ec6PDH (mutant) + ADP + 6PG<br />
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**[[3fwn]] - Ec6PDH (mutant) + ADP + 6PG<br />
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[[3pef]] – Gm6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose<br />
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**[[3pef]] – Gm6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose<br />
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[[3w6u]] – Pc6PDH + NADP + monophosphoadenosine diphosphoribose – ''Pyrobaculum calidifontis''<br />
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**[[3w6u]] – Pc6PDH + NADP + monophosphoadenosine diphosphoribose – ''Pyrobaculum calidifontis''<br />
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[[3w6z]] – Pc6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose <br />
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**[[3w6z]] – Pc6PDH (mutant) + NADP + monophosphoadenosine diphosphoribose <br />
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===6PDH quaternary complex===
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*6PDH quaternary complex
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[[2iyp]] - Ll6PDH + ADP + ribulose 5-phosphate + NADP<BR />
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[[2iz0]] - Ll6PDH + inhibitor + ADP + NADP<BR />
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**[[2iyp]] - Ll6PDH + ADP + ribulose 5-phosphate + NADP<BR />
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**[[2iz0]] - Ll6PDH + inhibitor + ADP + NADP<BR />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:25, 11 November 2014

Template:STRUCTURE 1pgj 6-phosphogluconate dehydrogenase (6PDH) catalyzes the decarboxylation reduction of 6-phosphogluconate (6PG) to ribulose 5-phosphate and CO2. This reaction is part of the pentose phosphate pathway. NADP is a cofactor in this reaction and is converted to NADPH.

</StructureSection>

3D structures of 6-phosphogluconate dehydrogenase (Updated on 11-November-2014)

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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