4m2x
From Proteopedia
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| - | ''' | + | ==Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ)== |
| - | + | <StructureSection load='4m2x' size='340' side='right' caption='[[4m2x]], [[Resolution|resolution]] 2.26Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4m2x]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M2X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TMQ:TRIMETREXATE'>TMQ</scene></td></tr> | |
| - | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m2x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m2x RCSB], [http://www.ebi.ac.uk/pdbsum/4m2x PDBsum]</span></td></tr> | |
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Jung, H]] | ||
| + | [[Category: Sacchettini, J C]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Hydride transfer]] | ||
| + | [[Category: Nadph binding]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
| + | [[Category: Reductase]] | ||
| + | [[Category: Tbsgc]] | ||
Revision as of 06:50, 12 November 2014
Mycobacterium tuberculosis dihydrofolate reductase complexed with trimetrexate (TMQ)
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