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2opp

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<StructureSection load='2opp' size='340' side='right' caption='[[2opp]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='2opp' size='340' side='right' caption='[[2opp]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2opp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OPP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2opp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OPP FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBQ:ISOPROPYL+(2S)-2-ETHYL-7-FLUORO-3-OXO-3,4-DIHYDROQUINOXALINE-1(2H)-CARBOXYLATE'>HBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HBQ:ISOPROPYL+(2S)-2-ETHYL-7-FLUORO-3-OXO-3,4-DIHYDROQUINOXALINE-1(2H)-CARBOXYLATE'>HBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSW:CYSTEINE-S-DIOXIDE'>CSW</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 M:B_HXB2R])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2opp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2opp RCSB], [http://www.ebi.ac.uk/pdbsum/2opp PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2opp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2opp RCSB], [http://www.ebi.ac.uk/pdbsum/2opp PDBsum]</span></td></tr>
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</table>
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<table>
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== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hiv-1 m:b_hxb2r]]
 
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: Chamberlain, P P.]]
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[[Category: Chamberlain, P P]]
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[[Category: Chan, S J.H.]]
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[[Category: Chan, S J.H]]
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[[Category: Kleim, J.]]
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[[Category: Kleim, J]]
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[[Category: Nichols, C E.]]
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[[Category: Nichols, C E]]
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[[Category: Ren, J.]]
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[[Category: Ren, J]]
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[[Category: Stammers, D K.]]
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[[Category: Stammers, D K]]
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[[Category: Weaver, K L.]]
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[[Category: Weaver, K L]]
[[Category: Aid]]
[[Category: Aid]]
[[Category: Drug resistance]]
[[Category: Drug resistance]]

Revision as of 07:19, 12 November 2014

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with GW420867X.

2opp, resolution 2.55Å

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