1kyh
From Proteopedia
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- | [[Image:1kyh.gif|left|200px]] | + | [[Image:1kyh.gif|left|200px]] |
- | + | ||
- | '''Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase''' | + | {{Structure |
+ | |PDB= 1kyh |SIZE=350|CAPTION= <scene name='initialview01'>1kyh</scene>, resolution 1.60Å | ||
+ | |SITE= | ||
+ | |LIGAND= | ||
+ | |ACTIVITY= | ||
+ | |GENE= YXKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis]) | ||
+ | }} | ||
+ | |||
+ | '''Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1KYH is a [ | + | 1KYH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KYH OCA]. |
==Reference== | ==Reference== | ||
- | Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase., Zhang RG, Grembecka J, Vinokour E, Collart F, Dementieva I, Minor W, Joachimiak A, J Struct Biol. 2002 Sep;139(3):161-70. PMID:[http:// | + | Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase., Zhang RG, Grembecka J, Vinokour E, Collart F, Dementieva I, Minor W, Joachimiak A, J Struct Biol. 2002 Sep;139(3):161-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12457846 12457846] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Zhang, R.]] | [[Category: Zhang, R.]] | ||
[[Category: mcsg]] | [[Category: mcsg]] | ||
- | [[Category: midwest center for structural | + | [[Category: midwest center for structural genomic]] |
[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
- | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: unknown function]] | [[Category: unknown function]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:23:54 2008'' |
Revision as of 10:23, 20 March 2008
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, resolution 1.60Å | |||||||
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Gene: | YXKO (Bacillus subtilis) | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Structure of Bacillus subtilis YxkO, a Member of the UPF0031 Family and a Putative Kinase
Overview
We determined the 1.6-A resolution crystal structure of a conserved hypothetical 29.9-kDa protein from the SIGY-CYDD intergenic region encoded by a Bacillus subtilis open reading frame in the YXKO locus. YXKO homologues are broadly distributed and are by and large described as proteins with unknown function. The YXKO protein has an alpha/beta fold and shows high structural homology to the members of a ribokinase-like superfamily. However, YXKO is the only member of this superfamily known to form tetramers. Putative binding sites for adenosine triphosphate (ATP), a substrate, and Mg(2+)-binding sites were revealed in the structure of the protein, based on high structural similarity to ATP-dependent members of the superfamily. Two adjacent monomers contribute residues to the active site. The crystal structure provides valuable information about the YXKO protein's tertiary and quaternary structure, the biochemical function of YXKO and its homologues, and the evolution of its ribokinase-like superfamily.
About this Structure
1KYH is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase., Zhang RG, Grembecka J, Vinokour E, Collart F, Dementieva I, Minor W, Joachimiak A, J Struct Biol. 2002 Sep;139(3):161-70. PMID:12457846
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