2xwg
From Proteopedia
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| - | [[ | + | ==CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII)== |
| + | <StructureSection load='2xwg' size='340' side='right' caption='[[2xwg]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2xwg]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomyces_oris Actinomyces oris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XWG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XWG FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xwg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xwg RCSB], [http://www.ebi.ac.uk/pdbsum/2xwg PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the sortase AcSrtC-1 from the oral microorganism Actinomyces oris has been determined to 2.4 A resolution. AcSrtC-1 is a cysteine transpeptidase that is responsible for the formation of fimbriae by the polymerization of a shaft protein. Similar to other pili-associated sortases, the AcSrtC-1 active site is protected by a flexible lid. The asymmetric unit contains five AcSrtC-1 molecules and their catalytic Cys-His-Arg triads are trapped in two different conformations. It is also shown that the thermostability of the enzyme is increased by the presence of calcium. | ||
| - | + | Structure of the sortase AcSrtC-1 from Actinomyces oris.,Persson K Acta Crystallogr D Biol Crystallogr. 2011 Mar;67(Pt 3):212-7. Epub 2011, Feb 15. PMID:21358052<ref>PMID:21358052</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Actinomyces oris]] | [[Category: Actinomyces oris]] | ||
| - | [[Category: Persson, K | + | [[Category: Persson, K]] |
[[Category: Fimbrial assembly]] | [[Category: Fimbrial assembly]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 08:19, 12 November 2014
CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII)
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