Arylamine N-acetyltransferase

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[1gx3]] – MsNAT – ''Mycobacterium smegmatis''<br />
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*Arylamine N-acetyltransferase
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[[1w5r]] – MsNAT (mutant)<br />
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[[2bsz]] – NAT1 – ''Rhizobium loti''<br />
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[[2ija]] – hNAT1 (mutant) – human<br />
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[[2pqt]] - hNAT1<br />
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[[2pfr]] – hNAT2<br />
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[[1w4t]] – NAT – ''Pseudomonas aeruginosa''<br />
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[[3d9w]] – NAT – ''Nocardia farcinica''<br />
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[[3lnb]] – NAT (mutant) – ''Bacillus anthracis''<br />
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[[2vfb]], [[4c5p]] - MmNAT – ''Mycobacterium marinum''<br />
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[[4bgf]] - NAT – ''Mycobacterium tuberculosis''<br />
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'''Arylamine N-acetyltransferase binary complex'''
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**[[1gx3]] – MsNAT – ''Mycobacterium smegmatis''<br />
 +
**[[1w5r]] – MsNAT (mutant)<br />
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**[[2bsz]] – NAT1 – ''Rhizobium loti''<br />
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**[[2ija]] – hNAT1 (mutant) – human<br />
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**[[2pqt]] - hNAT1<br />
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**[[2pfr]] – hNAT2<br />
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**[[1w4t]] – NAT – ''Pseudomonas aeruginosa''<br />
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**[[3d9w]] – NAT – ''Nocardia farcinica''<br />
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**[[3lnb]] – NAT (mutant) – ''Bacillus anthracis''<br />
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**[[2vfb]], [[4c5p]] - MmNAT – ''Mycobacterium marinum''<br />
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**[[4bgf]] - NAT – ''Mycobacterium tuberculosis''<br />
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[[2vfc]] – MmNAT + CoA<br />
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*Arylamine N-acetyltransferase binary complex
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[[3ltw]] – MmNAT + hydralazine<br />
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[[1w6f]] – MsNAT + anti-tubercular drug<br />
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[[4b55]] – MmNAT + piperidinol derivative<br />
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**[[2vfc]] – MmNAT + CoA<br />
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**[[3ltw]] – MmNAT + hydralazine<br />
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**[[1w6f]] – MsNAT + anti-tubercular drug<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:59, 17 November 2014

Template:STRUCTURE 3ltw

Arylamine N-acetyltransferase (NAT) catalyzes the transfer of an acetyl group from acetyl-CoA to an arylamine. Acetylation is a major route of biotransformation for many arylamines and hydrazine drugs and known carcinogens like cigarette smoke. The levels of NAT in the body has important consequences with regard to an individual’s susceptibility to certain drug-induced toxicities and cancer.

3D structures of arylamine N-acetyltransferase

Updated on 17-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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