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4g6w

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{{STRUCTURE_4g6w| PDB=4g6w | SCENE= }}
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==Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol==
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===Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol===
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<StructureSection load='4g6w' size='340' side='right' caption='[[4g6w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4g6w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4G6W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PBX:4-BROMOBENZENE-1,2,3-TRIOL'>PBX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ehi|3ehi]], [[4g2o|4g2o]], [[4gd7|4gd7]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tyms, ts, ok/sw-cl.29 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4g6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g6w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4g6w RCSB], [http://www.ebi.ac.uk/pdbsum/4g6w PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
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*[[Thymidylate synthase|Thymidylate synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4g6w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G6W OCA].
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[[Category: Human]]
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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[[Category: Celeste, L R.]]
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[[Category: Celeste, L R]]
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[[Category: Lebioda, L.]]
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[[Category: Lebioda, L]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 09:22, 19 November 2014

Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol

4g6w, resolution 2.30Å

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