4q3i
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q3i RCSB], [http://www.ebi.ac.uk/pdbsum/4q3i PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q3i RCSB], [http://www.ebi.ac.uk/pdbsum/4q3i PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Somatic embryogenesis receptor kinases (SERKs) are leucine-rich repeat (LRR)-containing integral membrane receptors that are involved in the regulation of development and immune responses in plants. It has recently been shown that rice SERK2 (OsSERK2) is essential for XA21-mediated resistance to the pathogen Xanthomonas oryzae pv. oryzae. OsSERK2 is also required for the BRI1-mediated, FLS2-mediated and EFR-mediated responses to brassinosteroids, flagellin and elongation factor Tu (EF-Tu), respectively. Here, crystal structures of the LRR domains of OsSERK2 and a D128N OsSERK2 mutant, expressed as hagfish variable lymphocyte receptor (VLR) fusions, are reported. These structures suggest that the aspartate mutation does not generate any significant conformational change in the protein, but instead leads to an altered interaction with partner receptors. | ||
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| + | Structure of the OsSERK2 leucine-rich repeat extracellular domain.,McAndrew R, Pruitt RN, Kamita SG, Pereira JH, Majumdar D, Hammock BD, Adams PD, Ronald PC Acta Crystallogr D Biol Crystallogr. 2014 Nov;70(Pt 11):3080-6. doi:, 10.1107/S1399004714021178. Epub 2014 Oct 29. PMID:25372696<ref>PMID:25372696</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 10:36, 19 November 2014
Structure of the OsSERK2 leucine rich repeat extracellular domain
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