Cadherin

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 6: Line 6:
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
{{#tree:id=OrganizedByTopic|openlevels=0|
-
=== CDH1 ===
+
* CDH1
-
[[1q1p]] – mCDH1 - mouse<br />
+
**[[1q1p]] – mCDH1 - mouse<br />
-
[[3q2v]] – mCDH1 ectodomain<br />
+
**[[3q2v]] – mCDH1 ectodomain<br />
-
[[3qrb]] – mCDH1+2
+
**[[3qrb]] – mCDH1+2
-
=== CDH5 ===
+
* CDH5
-
[[2koh]] – mCDH5+PAR3-PDZ3<br />
+
**[[2koh]] – mCDH5+PAR3-PDZ3<br />
-
=== CDH6 ===
+
* CDH6
-
[[3lnd]] – mCDH6 EC12 (mutant)<br />
+
**[[3lnd]] – mCDH6 EC12 (mutant)<br />
-
=== CDH8 ===
+
* CDH8
-
[[1zxk]] – mCDH8 EC1<br />
+
**[[1zxk]] – mCDH8 EC1<br />
-
[[2a62]] - mCDH8 EC1+EC2+EC3<br />
+
**[[2a62]] - mCDH8 EC1+EC2+EC3<br />
-
=== CDH11 ===
+
* CDH11
-
[[2a4c]], [[2a4e]] – mCDH11 EC1<br />
+
**[[2a4c]], [[2a4e]] – mCDH11 EC1<br />
-
=== CDH20 ===
+
* CDH20
-
[[1zvn]] – cCDH20 EC1 – chicken<br />
+
**[[1zvn]] – cCDH20 EC1 – chicken<br />
-
=== CDH23 ===
+
* CDH23
-
[[3mvs]], [[2whv]] – mCDH23 N-terminal<br />
+
**[[3mvs]], [[2whv]] – mCDH23 N-terminal<br />
-
[[2kbr]] – hCDH23 peptide+harmonin – NMR - human<br />
+
**[[2kbr]] – hCDH23 peptide+harmonin – NMR - human<br />
-
[[2kbs]] - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR<br />
+
**[[2kbs]] - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR<br />
-
[[2wbx]] – mCDH23 EC1<br />
+
**[[2wbx]] – mCDH23 EC1<br />
-
[[2wcp]] - mCDH23 EC2<br />
+
**[[2wcp]] - mCDH23 EC2<br />
-
[[2wd0]] - mCDH23 EC1+EC2 (mutant)<br />
+
**[[2wd0]] - mCDH23 EC1+EC2 (mutant)<br />
-
[[4apx]], [[4aq8]], [[4axw]] - mCDH23 EC1+EC2 + Prot-CDH15<br />
+
**[[4apx]], [[4aq8]], [[4axw]] - mCDH23 EC1+EC2 + Prot-CDH15<br />
-
[[4aqa]], [[4aqe]] - mCDH23 EC1+EC2 (mutant) + Prot-CDH15
+
**[[4aqa]], [[4aqe]] - mCDH23 EC1+EC2 (mutant) + Prot-CDH15
-
=== C-CDH “classical” ===
+
* C-CDH “classical”
-
[[1l3w]] – XlC-CDH ectodomain - ''Xenopus laevis''<br />
+
**[[1l3w]] – XlC-CDH ectodomain - ''Xenopus laevis''<br />
-
[[1q5b]], [[1q5c]], [[1q55]], [[1q5a]] – C-CDH model into desmosome – electron tomography<br />
+
**[[1q5b]], [[1q5c]], [[1q55]], [[1q5a]] – C-CDH model into desmosome – electron tomography<br />
-
=== E-CDH epithelial ===
+
* E-CDH epithelial
-
[[1ff5]] – mE-CDH double domain<br />
+
**[[1edh]] - mE-CDH EC1+EC2+Ca<br />
-
[[1edh]] - mE-CDH EC1+EC2+Ca<br />
+
**[[3q2l]], [[3q2n]] - mE-CDH EC1+EC2 (mutant)<br />
-
[[3q2l]], [[3q2n]] - mE-CDH EC1+EC2 (mutant)<br />
+
**[[1suh]] – mE-CDH N-terminal - NMR<br />
-
[[1suh]] – mE-CDH N-terminal - NMR<br />
+
**[[3l6x]], [[3l6y]], [[1i7x]], [[1i7w]] – mE-CDH+catenin<br />
-
[[3l6x]], [[3l6y]], [[1i7x]], [[1i7w]] – mE-CDH+catenin<br />
+
**[[3lne]], [[3lnf]], [[3lng]], [[3lnh]], [[3lni]] – mE-CDH EC12 (mutant)<br />
-
[[3lne]], [[3lnf]], [[3lng]], [[3lnh]], [[3lni]] – mE-CDH EC12 (mutant)<br />
+
**[[2qvf]] – mE-CDH1 CDH2<br />
-
[[2qvf]] – mE-CDH1 CDH2<br />
+
**[[3ifq]] – hE-CDH EC1+EC2+EC3 <br />
-
[[3ifq]] – hE-CDH EC1+EC2+EC3 <br />
+
**[[2o72]] - hE-CDH EC1+EC2<br />
-
[[2o72]] - hE-CDH EC1+EC2<br />
+
**[[3ff7]], [[3ff8]] - hE-CDH EC1+EC2+EC3+NK cell receptor<br />
-
[[3ff7]], [[3ff8]] - hE-CDH EC1+EC2+EC3+NK cell receptor<br />
+
**[[2omt]], [[2omu]], [[2omx]], [[2omz]], [[2omv]], [[2omw]], [[2omy]] – hE-CDH EC1+internalin (mutant)<br />
-
[[2omt]], [[2omu]], [[2omx]], [[2omz]], [[2omv]], [[2omw]], [[2omy]] – hE-CDH EC1+internalin (mutant)<br />
+
**[[1o6s]] – E-CDH N-terminal+internalin – ''Listeria monocytogenes''<br />
-
[[1o6s]] – E-CDH N-terminal+internalin – ''Listeria monocytogenes''<br />
+
-
=== T-CDH membrane bound ===
+
* T-CDH membrane bound
-
[[3k5r]] – mT-CDH EC1+EC2<br />
+
**[[3k5r]] – mT-CDH EC1+EC2<br />
-
[[3k5s]] - cT-CDH EC1+EC2 <br />
+
**[3k5s]] - cT-CDH EC1+EC2 <br />
-
[[3k6d]] - XlT-CDH EC1 <br />
+
**[[3k6d]] - XlT-CDH EC1 <br />
-
[[3k6f]] - mT-CDH EC1<br />
+
**[[3k6f]] - mT-CDH EC1<br />
-
[[3k6i]] - cT-CDH EC1<br />
+
**[[3k6i]] - cT-CDH EC1<br />
-
[[2v37]] – hT-CDH N-terminal - NMR<br />
+
**[[2v37]] – hT-CDH N-terminal - NMR<br />
-
=== N-CDH neuronal ===
+
* N-CDH neuronal
-
[[1nch]], [[1nci]] – mN-CDH<br />
+
**[[1nch]], [[1nci]] – mN-CDH<br />
-
[[1ncg]] – mN-CDH (mutant)<br />
+
**[[1ncg]] – mN-CDH (mutant)<br />
-
[[2qvi]] – mN-CDH EC12<br />
+
**[[1ncj]] – mN-CDH two domains<br />
-
[[1ncj]] – mN-CDH two domains<br />
+
**[[3q2w]] – mN-CDH ectodomain<br />
-
[[3q2w]] – mN-CDH ectodomain<br />
+
**[[1op4]] - mN-CDH prodomain - NMR<br />
-
[[1op4]] - mN-CDH prodomain - NMR<br />
+
**[[3ubf]] – DmN-CDH ectodomain – ''Drosophila melanogaster''<br />
-
[[3ubf]] – DmN-CDH ectodomain – ''Drosophila melanogaster''<br />
+
**[[3ubh]] - DmN-CDH EC1-4<br />
-
[[3ubh]] - DmN-CDH EC1-4<br />
+
**[[3ubg]] - DmN-CDH EC1-3
-
[[3ubg]] - DmN-CDH EC1-
+
-
===VE-CDH vascular epithelial===
+
*VE-CDH vascular epithelial
-
[[3ppe]] – cVE-CDH EC1+EC2<br />
+
**[[3ppe]] – cVE-CDH EC1+EC2<br />
-
=== Protocadherin ===
+
* Protocadherin
-
[[2yst]] – hProt-CDH7 EC3 – NMR<br />
+
**[[2yst]] – hProt-CDH7 EC3 – NMR<br />
-
[[2ee0]] - hProt-CDH9 Ca domain – NMR<br />
+
**[[2ee0]] - hProt-CDH9 Ca domain – NMR<br />
-
[[1wyj]] - mProt-CDH β 14 - NMR<br />
+
**[[1wyj]] - mProt-CDH β 14 - NMR<br />
-
[[1wuz]] - mProt-CDH4 EC1 – NMR
+
**[[1wuz]] - mProt-CDH4 EC1 – NMR
-
=== Desmoglein ===
+
* Desmoglein
-
 
+
-
[[2yqg]] – hDes-CDH EC1<br />
+
 +
**[[2yqg]] – hDes-CDH EC1<br />
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:16, 19 November 2014

Template:STRUCTURE 1q1p

Cadherins (CDH) are calcium-dependent adhesion proteins. They contain extracellular CDH repeats (EC1-EC5) which bind calcium ions. They are encoded by numerous genes numbered CDH1-CDH23. Some names of CDH indicate their locations: E-CDH (epithelial tissue), VE-CDH (vascular epithelial), T-CDH bound to membrane, N-CDH (neurons). The CDH superfamily contains protocadhedrins (Prot-CDH), desmogleins (Des-CDH) and more. Calcium ions are shown as a space filling objects.

3D Structures of Cadherin

Updated on 19-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Retrieved from "http://52.214.119.220/wiki/index.php/Cadherin"
Personal tools