1lcn

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[[Image:1lcn.jpg|left|200px]]<br /><applet load="1lcn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1lcn.jpg|left|200px]]
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caption="1lcn, resolution 1.63&Aring;" />
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'''Monoclinic hen egg white lysozyme, thiocyanate complex'''<br />
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{{Structure
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|PDB= 1lcn |SIZE=350|CAPTION= <scene name='initialview01'>1lcn</scene>, resolution 1.63&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SCN:THIOCYANATE ION'>SCN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]
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|GENE=
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}}
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'''Monoclinic hen egg white lysozyme, thiocyanate complex'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1LCN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=SCN:'>SCN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCN OCA].
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1LCN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCN OCA].
==Reference==
==Reference==
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Structural effects of monovalent anions on polymorphic lysozyme crystals., Vaney MC, Broutin I, Retailleau P, Douangamath A, Lafont S, Hamiaux C, Prange T, Ducruix A, Ries-Kautt M, Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):929-40. Epub 2001, Jun 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11418760 11418760]
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Structural effects of monovalent anions on polymorphic lysozyme crystals., Vaney MC, Broutin I, Retailleau P, Douangamath A, Lafont S, Hamiaux C, Prange T, Ducruix A, Ries-Kautt M, Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):929-40. Epub 2001, Jun 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11418760 11418760]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
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[[Category: lysozyme]]
[[Category: lysozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:43:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:29:21 2008''

Revision as of 10:29, 20 March 2008


PDB ID 1lcn

Drag the structure with the mouse to rotate
, resolution 1.63Å
Ligands:
Activity: Lysozyme, with EC number 3.2.1.17
Coordinates: save as pdb, mmCIF, xml



Monoclinic hen egg white lysozyme, thiocyanate complex


Overview

Understanding direct salt effects on protein crystal polymorphism is addressed by comparing different crystal forms (triclinic, monoclinic, tetragonal and orthorhombic) for hen, turkey, bob white quail and human lysozymes. Four new structures of hen egg-white lysozyme are reported: crystals grown in the presence of NapTS diffracted to 1.85 A, of NaI to 1.6 A, of NaNO(3) to 1.45 A and of KSCN to 1.63 A. These new structures are compared with previously published structures in order to draw a mapping of the surface of different lysozymes interacting with monovalent anions, such as nitrate, chloride, iodide, bromide and thiocyanate. An analysis of the structural sites of these anions in the various lysozyme structures is presented. This study shows common anion sites whatever the crystal form and the chemical nature of anions, while others seem specific to a given geometry and a particular charge environment induced by the crystal packing.

About this Structure

1LCN is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Structural effects of monovalent anions on polymorphic lysozyme crystals., Vaney MC, Broutin I, Retailleau P, Douangamath A, Lafont S, Hamiaux C, Prange T, Ducruix A, Ries-Kautt M, Acta Crystallogr D Biol Crystallogr. 2001 Jul;57(Pt 7):929-40. Epub 2001, Jun 21. PMID:11418760

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