4nkf

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'''Unreleased structure'''
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==The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates==
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<StructureSection load='4nkf' size='340' side='right' caption='[[4nkf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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The entry 4nkf is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nkf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NKF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NKF FirstGlance]. <br>
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Authors: Tsoumpra, M.K., Barnett, B.L., Muniz, J.R.C., Walter, R.L., Ebetino, F.H., Von Delft, F., Russell, R.G.G., Oppermann, U., Dunford, J.E.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=210:PAMIDRONATE'>210</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n9u|4n9u]], [[4ng6|4ng6]], [[1yq7|1yq7]], [[1zw5|1zw5]], [[4nke|4nke]], [[4nua|4nua]]</td></tr>
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Description: The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nkf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nkf RCSB], [http://www.ebi.ac.uk/pdbsum/4nkf PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Barnett, B L]]
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[[Category: Delft, F Von]]
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[[Category: Dunford, J E]]
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[[Category: Ebetino, F H]]
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[[Category: Muniz, J R.C]]
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[[Category: Oppermann, U]]
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[[Category: Russell, R G.G]]
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[[Category: Tsoumpra, M K]]
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[[Category: Walter, R L]]
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[[Category: Alpha-helical prenyltransferase]]
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[[Category: Bisphosphonate]]
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[[Category: Cholesterol synthesis]]
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[[Category: Isoprene biosynthesis]]
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[[Category: Isoprenoid pathway]]
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[[Category: Lipid synthesis]]
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[[Category: Steroid biosynthesis]]
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[[Category: Transferase]]

Revision as of 12:50, 19 November 2014

The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates

4nkf, resolution 2.00Å

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