4ped
From Proteopedia
(Difference between revisions)
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| - | ''' | + | ==Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes== |
| - | + | <StructureSection load='4ped' size='340' side='right' caption='[[4ped]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ped]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PED FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ped FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ped OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ped RCSB], [http://www.ebi.ac.uk/pdbsum/4ped PDBsum]</span></td></tr> | |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/ADCK3_HUMAN ADCK3_HUMAN]] Autosomal recessive ataxia due to ubiquinone deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ADCK3_HUMAN ADCK3_HUMAN]] Putative protein kinase involved in the biosynthesis of coenzyme Q since it is able to rescue partially coenzyme Q6 biosynthesis of yeast COQ8 mutants. May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain.<ref>PMID:21296186</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Barber, G E]] | ||
| + | [[Category: Bingman, C A]] | ||
| + | [[Category: Coon, J J]] | ||
| + | [[Category: Floyd, B J]] | ||
| + | [[Category: Jochem, A]] | ||
| + | [[Category: Johnson, I E]] | ||
| + | [[Category: Joshi, S]] | ||
| + | [[Category: Kannan, N]] | ||
| + | [[Category: Lee, D]] | ||
| + | [[Category: Li, S]] | ||
| + | [[Category: MPP, Mitochondrial Protein Partnership]] | ||
| + | [[Category: Oruganty, O]] | ||
| + | [[Category: Pagliarini, D J]] | ||
| + | [[Category: Reidenbach, A G]] | ||
| + | [[Category: Saunders, J M]] | ||
| + | [[Category: Smith, R]] | ||
| + | [[Category: Stefely, J A]] | ||
| + | [[Category: Ulbrich, A]] | ||
| + | [[Category: Wrobel, R L]] | ||
| + | [[Category: Coenzyme q biosynthesis]] | ||
| + | [[Category: Membrane associated]] | ||
| + | [[Category: Mitochondrial]] | ||
| + | [[Category: Mitochondrial protein partnership]] | ||
| + | [[Category: Mpp]] | ||
| + | [[Category: Protein kinase-like]] | ||
| + | [[Category: Psi-biology]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 12:53, 19 November 2014
Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes
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Categories: Barber, G E | Bingman, C A | Coon, J J | Floyd, B J | Jochem, A | Johnson, I E | Joshi, S | Kannan, N | Lee, D | Li, S | MPP, Mitochondrial Protein Partnership | Oruganty, O | Pagliarini, D J | Reidenbach, A G | Saunders, J M | Smith, R | Stefely, J A | Ulbrich, A | Wrobel, R L | Coenzyme q biosynthesis | Membrane associated | Mitochondrial | Mitochondrial protein partnership | Mpp | Protein kinase-like | Psi-biology | Structural genomic | Transferase
