1lfp
From Proteopedia
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| - | [[Image:1lfp.gif|left|200px]] | + | [[Image:1lfp.gif|left|200px]] |
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| - | '''Crystal Structure of a Conserved Hypothetical Protein Aq1575 from Aquifex Aeolicus''' | + | {{Structure |
| + | |PDB= 1lfp |SIZE=350|CAPTION= <scene name='initialview01'>1lfp</scene>, resolution 1.72Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''Crystal Structure of a Conserved Hypothetical Protein Aq1575 from Aquifex Aeolicus''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1LFP is a [ | + | 1LFP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LFP OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of conserved hypothetical protein Aq1575 from Aquifex aeolicus., Shin DH, Yokota H, Kim R, Kim SH, Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7980-5. PMID:[http:// | + | Crystal structure of conserved hypothetical protein Aq1575 from Aquifex aeolicus., Shin DH, Yokota H, Kim R, Kim SH, Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7980-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12060744 12060744] |
[[Category: Aquifex aeolicus]] | [[Category: Aquifex aeolicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi]] | [[Category: psi]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: thermostability]] | [[Category: thermostability]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:30:23 2008'' |
Revision as of 10:30, 20 March 2008
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| , resolution 1.72Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of a Conserved Hypothetical Protein Aq1575 from Aquifex Aeolicus
Overview
The crystal structure of a conserved hypothetical protein, Aq1575, from Aquifex aeolicus has been determined by using x-ray crystallography. The protein belongs to the domain of unknown function DUF28 in the Pfam and PALI databases for which there was no structural information available until now. A structural homology search with the DALI algorithm indicates that this protein has a new fold with no obvious similarity to those of other proteins of known three-dimensional structure. The protein reveals a monomer consisting of three domains arranged along a pseudo threefold symmetry axis. There is a large cleft with approximate dimensions of 10 A x 10 A x 20 A in the center of the three domains along the symmetry axis. Two possible active sites are suggested based on the structure and multiple sequence alignment. There are several highly conserved residues in these putative active sites. The structure based molecular properties and thermostability of the protein are discussed.
About this Structure
1LFP is a Single protein structure of sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.
Reference
Crystal structure of conserved hypothetical protein Aq1575 from Aquifex aeolicus., Shin DH, Yokota H, Kim R, Kim SH, Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7980-5. PMID:12060744
Page seeded by OCA on Thu Mar 20 12:30:23 2008
Categories: Aquifex aeolicus | Single protein | BSGC, Berkeley Structural Genomics Center. | Kim, R. | Kim, S H. | Shin, D H. | Yokota, H. | Berkeley structural genomics center | Bsgc structure funded by nih | Hypothetical | New fold | Protein structure initiative | Psi | Structural genomic | Thermostability
