CD1

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'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules.
'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules.
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== 3D Structures of CD1 ==
== 3D Structures of CD1 ==

Revision as of 14:00, 19 November 2014

Structure of mouse CD1 extracellular domain (grey) containing β-microglobulin (green) complex with glycolipid (PDB entry 3ilp)

Drag the structure with the mouse to rotate

3D Structures of CD1

Updated on 19-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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