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Chitinase

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{{STRUCTURE_1edq| PDB=1edq | SIZE=400| SCENE=Chitinases/Cv/2 |right|CAPTION=Chitinase I from ''Serratia marcescens'', [[1edq]] }}
{{STRUCTURE_1edq| PDB=1edq | SIZE=400| SCENE=Chitinases/Cv/2 |right|CAPTION=Chitinase I from ''Serratia marcescens'', [[1edq]] }}
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 +
Chitinase-3-like protein 1
-
===Chitinase I===
+
*Chitinase I
-
 
+
-
[[3aro]], [[3b8s]] – VhChi residues 22-597 – ''Vibrio harveyi''<br />
+
-
[[3b9e]] - VhChi residues 22-597 (mutant)<br />
+
-
[[1k85]] – BcChi fibronectin domain – ''Bacillus circulans'' – NMR<br />
+
-
[[1itx]] - BcChi catalytic domain<br />
+
-
[[1ed7]] – BcChi chitin-binding domain - NMR<br />
+
-
[[1ll6]], [[1ll7]] - CiChi residues 36-427 (mutant) – ''Coccicioides immitis'' <br />
+
-
[[1d2k]] - CiChi residues 36-427<br />
+
-
[[3n11]] – BcChi – ''Bacillus cereus''<br />
+
-
[[3iwr]], [[2dkv]] – Chi residues 33-340 – Japanese rice<br />
+
-
[[1edq]], [[1ctn]], [[4axn]] - SmChi – ''Serratia marcescens''<br />
+
-
[[1x6l]], [[1rd6]] – SmChi (mutant)<br />
+
-
[[3g6l]] - BoChi residues 21-426 – ''Bionectria ochroleuca''<br />
+
-
[[3oa5]], [[4dws]] – Chi – ''Yersinia entomophaga''<br />
+
-
[[3w4r]] – Chi – corn borer<br />
+
-
''Chitinase I binary complex''
+
**[[3aro]], [[3b8s]] – VhChi residues 22-597 – ''Vibrio harveyi''<br />
 +
**[[3b9e]] - VhChi residues 22-597 (mutant)<br />
 +
**[[1k85]] – BcChi fibronectin domain – ''Bacillus circulans'' – NMR<br />
 +
**[[1itx]] - BcChi catalytic domain<br />
 +
**[[1ed7]] – BcChi chitin-binding domain - NMR<br />
 +
**[[1ll6]], [[1ll7]] - CiChi residues 36-427 (mutant) – ''Coccicioides immitis'' <br />
 +
**[[1d2k]] - CiChi residues 36-427<br />
 +
**[[3n11]] – BcChi – ''Bacillus cereus''<br />
 +
**[[3iwr]], [[2dkv]] – Chi residues 33-340 – Japanese rice<br />
 +
**[[1edq]], [[1ctn]], [[4axn]] - SmChi – ''Serratia marcescens''<br />
 +
**[[1x6l]], [[1rd6]] – SmChi (mutant)<br />
 +
**[[3g6l]] - BoChi residues 21-426 – ''Bionectria ochroleuca''<br />
 +
**[[3oa5]], [[4dws]] – Chi – ''Yersinia entomophaga''<br />
 +
**[[3w4r]] – Chi – corn borer<br />
-
[[3arp]], [[3arq]], [[3arr]], [[3ars]], [[3art]], [[3aru]], [[3arv]], [[3arw]], [[3arx]], [[3ary]], [[3arz]] – VhChi residues 22-597 + inhibitor<br />
+
*''Chitinase I binary complex''
-
[[3as0]], [[3as1]], [[3as2]], [[3as3]] – VhChi residues 22-597 (mutant) + inhibitor<br />
+
-
[[3b9a]], [[3b9d]] - VhChi residues 22-597 + polysaccharide<br />
+
-
[[2xvn]], [[2xuc]] – AfChi residues 29-307 + inhibitor – ''Aspergillus fumigatus''<br />
+
-
[[3n13]], [[3n15]], [[3n17]], [[3n18]] – BcChi (mutant) + NAG<br />
+
-
[[3n12]] – BcChi + Zn<br />
+
-
[[3n1a]] - BcChi (mutant) + inhibitor<br />
+
-
[[1x6n]] - SmChi (mutant) + inhibitor<br />
+
-
[[1ffq]] - SmChi + inhibitor<br />
+
-
[[1nh6]], [[1k9t]], [[1ffr]], [[1eib]], [[1ehn]] - SmChi (mutant) + polysaccharide<br />
+
-
[[2wk2]], [[2wly]], [[2wlz]], [[2wm0]] – SmChi residues 2-520 + inhibitor <br />
+
-
[[3g6m]] - BoChi residues 21-426 + caffeine<br />
+
-
[[1waw]], [[1wb0]] – hChi catalytic domain polypeptide – human<br />
+
-
[[1hkk]], [[1hkm]], [[3rm4]], [[3rm8]], [[3rm9]], [[3rme]] – hChi catalytic domain inhibitor<br />
+
-
[[1ll4]] - CiChi residues 36-427 + inhibitor<br />
+
-
===Chitinase II===
+
**[[3arp]], [[3arq]], [[3arr]], [[3ars]], [[3art]], [[3aru]], [[3arv]], [[3arw]], [[3arx]], [[3ary]], [[3arz]] – VhChi residues 22-597 + inhibitor<br />
 +
**[[3as0]], [[3as1]], [[3as2]], [[3as3]] – VhChi residues 22-597 (mutant) + inhibitor<br />
 +
**[[3b9a]], [[3b9d]] - VhChi residues 22-597 + polysaccharide<br />
 +
**[[2xvn]], [[2xuc]] – AfChi residues 29-307 + inhibitor – ''Aspergillus fumigatus''<br />
 +
**[[3n13]], [[3n15]], [[3n17]], [[3n18]] – BcChi (mutant) + NAG<br />
 +
**[[3n12]] – BcChi + Zn<br />
 +
**[[3n1a]] - BcChi (mutant) + inhibitor<br />
 +
**[[1x6n]] - SmChi (mutant) + inhibitor<br />
 +
**[[1ffq]] - SmChi + inhibitor<br />
 +
**[[1nh6]], [[1k9t]], [[1ffr]], [[1eib]], [[1ehn]] - SmChi (mutant) + polysaccharide<br />
 +
**[[2wk2]], [[2wly]], [[2wlz]], [[2wm0]] – SmChi residues 2-520 + inhibitor <br />
 +
**[[3g6m]] - BoChi residues 21-426 + caffeine<br />
 +
**[[1waw]], [[1wb0]] – hChi catalytic domain polypeptide – human<br />
 +
**[[1hkk]], [[1hkm]], [[3rm4]], [[3rm8]], [[3rm9]], [[3rme]] – hChi catalytic domain inhibitor<br />
 +
**[[1ll4]] - CiChi residues 36-427 + inhibitor<br />
-
[[1e15]], [[3wd0]] - SmChi<br />
+
*Chitinase II
-
[[1ogb]], [[1goi]], [[1e6p]] - SmChi (mutant)<br />
+
-
[[1kfw]] – Chi catalytic domain – Arthrobacter<br />
+
-
[[1dxj]] – Chi – Jack bean<br />
+
-
''Chitinase II binary complex''
+
**[[1e15]], [[3wd0]] - SmChi<br />
 +
**[[1ogb]], [[1goi]], [[1e6p]] - SmChi (mutant)<br />
 +
**[[1kfw]] – Chi catalytic domain – Arthrobacter<br />
 +
**[[1dxj]] – Chi – Jack bean<br />
-
[[1ogg]], [[1ur9]] - SmChi (mutant) + inhibitor<br />
+
*''Chitinase II binary complex''
-
[[1e6n]] - SmChi (mutant) + polysaccharide<br />
+
-
[[1ur8]], [[1gpf]], [[1e6r]], [[3wd1]], [[3wd2]], [[3wd3]], [[3wd4]] - SmChi + inhibitor<br />
+
-
[[1e6z]] – SmChi + intermediate<br />
+
-
[[2a3a]], [[2a3b]], [[2a3c]], [[2a3e]] – AfChi + inhibitor<br />
+
-
[[1w1p]], [[1w1t]], [[1w1v]], [[1w1y]], [[1o6i]], [[1h0g]], [[1h0i]] – SmChi + polypeptide<br />
+
-
===Chitinase III===
+
**[[1ogg]], [[1ur9]] - SmChi (mutant) + inhibitor<br />
 +
**[[1e6n]] - SmChi (mutant) + polysaccharide<br />
 +
**[[1ur8]], [[1gpf]], [[1e6r]], [[3wd1]], [[3wd2]], [[3wd3]], [[3wd4]] - SmChi + inhibitor<br />
 +
**[[1e6z]] – SmChi + intermediate<br />
 +
**[[2a3a]], [[2a3b]], [[2a3c]], [[2a3e]] – AfChi + inhibitor<br />
 +
**[[1w1p]], [[1w1t]], [[1w1v]], [[1w1y]], [[1o6i]], [[1h0g]], [[1h0i]] – SmChi + polypeptide<br />
-
[[2dbt]], [[1wvu]] – SgChi residues 30-294 – ''Streptomyces griseus''<br />
+
*Chitinase III
-
[[1wvv]] - SgChi residues 30-294 (mutant)<br />
+
-
[[2d49]] – SgChi chitin-binding domain - NMR<br />
+
-
[[2xvp]] – AfChi<br />
+
-
[[2xtk]] – AfChi + inhibitor
+
-
===Chitinase IV===
+
**[[2dbt]], [[1wvu]] – SgChi residues 30-294 – ''Streptomyces griseus''<br />
 +
**[[1wvv]] - SgChi residues 30-294 (mutant)<br />
 +
**[[2d49]] – SgChi chitin-binding domain - NMR<br />
 +
**[[2xvp]] – AfChi<br />
 +
**[[2xtk]] – AfChi + inhibitor
-
[[3hbd]], [[3hbe]], [[3hbh]] - Chi catalytic domain – Norway spruce<br />
+
*Chitinase IV
-
===Chitinase V===
+
**[[3hbd]], [[3hbe]], [[3hbh]] - Chi catalytic domain – Norway spruce<br />
-
[[3alf]] – tChi residues 26-377 – tobacco<br />
+
*Chitinase V
-
''Chitinase V binary complex''
+
**[[3alf]] – tChi residues 26-377 – tobacco<br />
-
[[3alg]] - tChi residues 26-377 (mutant) + NAG<br />
+
*''Chitinase V binary complex''
-
[[3chc]], [[3chd]], [[3che]], [[3chf]] - AfChi + polypeptide<br />
+
-
[[3ch9]], [[2iuz]] – AfChi + inhibitor<br />
+
-
===Chitinase VIII===
+
**[[3alg]] - tChi residues 26-377 (mutant) + NAG<br />
 +
**[[3chc]], [[3chd]], [[3che]], [[3chf]] - AfChi + polypeptide<br />
 +
**[[3ch9]], [[2iuz]] – AfChi + inhibitor<br />
-
[[2cjl]] - Chi residues 41-244 – ''Streptomyces coelicolor''<br />
+
*Chitinase VIII
-
===Chitinase XVIII===
+
**[[2cjl]] - Chi residues 41-244 – ''Streptomyces coelicolor''<br />
-
[[3sim]] – Chi – ''Crocus vernus''
+
*Chitinase XVIII
-
===Chitinase C===
+
**[[3sim]] – Chi – ''Crocus vernus''
-
[[4dyg]] – RyChiC + NAG – Rye<br />
+
*Chitinase C
-
[[4dwx]] - RyChiC<br />
+
-
[[4j0l]] – RyChiC + GlcNAC<br />
+
-
===Chitinase===
+
**[[4dyg]] – RyChiC + NAG – Rye<br />
 +
**[[4dwx]] - RyChiC<br />
 +
**[[4j0l]] – RyChiC + GlcNAC<br />
-
[[1wno]], [[1w9p]] - AfChi<br />
+
*Other chitinases
-
[[2dsk]] - PfChi catalytic domain – ''Pyrococcus furiosus''<br />
+
-
[[3afb]] - PfChi catalytic domain (mutant)<br />
+
-
[[1cns]] – Chi – ''Hordeum vulgare''<br />
+
-
[[2czn]] - PfChi chitin-binding domain – NMR<br />
+
-
[[2cwr]] - PfChi chitin-binding domain<br />
+
-
[[3ian]] – Chi (mutant) – ''Lactococcus lactis''<br />
+
-
[[3fxy]] - hChi catalytic domain<br />
+
-
[[1lq0]] - hChi residues 22-286<br />
+
-
[[1guv]] - hChi residues 22-387<br />
+
-
[[3fnd]], [[3co4]] – Chi – ''Bacteroides thetaiotamicron''<br />
+
-
[[3cql]] – Chi – ''Carica papaya''<br />
+
-
[[2z37]] - BjChi catalytic domain – ''Brassica juncea''<br />
+
-
[[2z39]] – BjChi catalytic domain (mutant)<br />
+
-
[[2uy2]] – yChi residues 22-315 – yeast<br />
+
-
[[4hmc]] – MmChi 60 – ''Moritella marina''<br />
+
-
[[3w3e]] – Chi – cowpea<br />
+
-
[[3w6b]] – RaChi catalytic domain – ''Ralstonia''<br />
+
-
[[3w6e]] – RaChi catalytic domain (mutant) <br />
+
-
''Chitinase binary complex''
+
**[[1wno]], [[1w9p]] - AfChi<br />
 +
**[[2dsk]] - PfChi catalytic domain – ''Pyrococcus furiosus''<br />
 +
**[[3afb]] - PfChi catalytic domain (mutant)<br />
 +
**[[1cns]] – Chi – ''Hordeum vulgare''<br />
 +
**[[2czn]] - PfChi chitin-binding domain – NMR<br />
 +
**[[2cwr]] - PfChi chitin-binding domain<br />
 +
**[[3ian]] – Chi (mutant) – ''Lactococcus lactis''<br />
 +
**[[3fxy]] - hChi catalytic domain<br />
 +
**[[1lq0]] - hChi residues 22-286<br />
 +
**[[1guv]] - hChi residues 22-387<br />
 +
**[[3fnd]], [[3co4]] – Chi – ''Bacteroides thetaiotamicron''<br />
 +
**[[3cql]] – Chi – ''Carica papaya''<br />
 +
**[[2z37]] - BjChi catalytic domain – ''Brassica juncea''<br />
 +
**[[2z39]] – BjChi catalytic domain (mutant)<br />
 +
**[[2uy2]] – yChi residues 22-315 – yeast<br />
 +
**[[4hmc]] – MmChi 60 – ''Moritella marina''<br />
 +
**[[3w3e]] – Chi – cowpea<br />
 +
**[[3w6b]] – RaChi catalytic domain – ''Ralstonia''<br />
 +
**[[3w6e]] – RaChi catalytic domain (mutant) <br />
-
[[3a4w]], [[3a4x]] – PfChi catalytic domain (mutant) + NAG<br />
+
*''Other chitinases binary complex''
-
[[1lg1]] - hChi residues 22-387 + chitobiose<br />
+
-
[[1lg2]] - hChi residues 22-387 + ethylene glycol<br />
+
-
[[3fy1]], [[2ybt]], [[2ybu]] - hChi catalytic domain + inhibitor<br />
+
-
[[1hki]], [[1hkj]] - hChi + inhibitor<br />
+
-
[[2z38]] - BjChi catalytic domain + Cl<br />
+
-
[[2uy3]], [[2uy4]], [[2uy5]] - yChi residues 22-315 + inhibitor<br />
+
-
[[1w9v]], [[1w9u]] - AfChi + polypeptide<br />
+
-
[[4hmd]] – MmChi 60 + intermediate<br />
+
-
[[4hme]] – MmChi 60 + NAG<br />
+
-
[[3w6c]] – RaChi catalytic domain + disaccharide<br />
+
-
[[3w6d]], [[3w6f]] – RaChi catalytic domain (mutant) + polysaccharide<br />
+
 +
**[[3a4w]], [[3a4x]] – PfChi catalytic domain (mutant) + NAG<br />
 +
**[[1lg1]] - hChi residues 22-387 + chitobiose<br />
 +
**[[1lg2]] - hChi residues 22-387 + ethylene glycol<br />
 +
**[[3fy1]], [[2ybt]], [[2ybu]] - hChi catalytic domain + inhibitor<br />
 +
**[[1hki]], [[1hkj]] - hChi + inhibitor<br />
 +
**[[2z38]] - BjChi catalytic domain + Cl<br />
 +
**[[2uy3]], [[2uy4]], [[2uy5]] - yChi residues 22-315 + inhibitor<br />
 +
**[[1w9v]], [[1w9u]] - AfChi + polypeptide<br />
 +
**[[4hmd]] – MmChi 60 + intermediate<br />
 +
**[[4hme]] – MmChi 60 + NAG<br />
 +
**[[3w6c]] – RaChi catalytic domain + disaccharide<br />
 +
**[[3w6d]], [[3w6f]] – RaChi catalytic domain (mutant) + polysaccharide<br />
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:53, 20 November 2014

Template:STRUCTURE 1edq

Chitinases cleave the beta-1-4-glycosidic bond between the N-acetyl-D-glucosamine units of which chitin is comprised. Chitinases are present in plants, bacteria and fungi. The first chitinase structures were solved in 1994, from a bacterium (1ctn) and a plant (2hvm). A mechanism for chitin cleavage was proposed based on several structures and was later confirmed.

3D Structures of Chitinase

Updated on 20-November-2014 Chitinase-3-like protein 1

  • Chitinase I
    • 3aro, 3b8s – VhChi residues 22-597 – Vibrio harveyi
    • 3b9e - VhChi residues 22-597 (mutant)
    • 1k85 – BcChi fibronectin domain – Bacillus circulans – NMR
    • 1itx - BcChi catalytic domain
    • 1ed7 – BcChi chitin-binding domain - NMR
    • 1ll6, 1ll7 - CiChi residues 36-427 (mutant) – Coccicioides immitis
    • 1d2k - CiChi residues 36-427
    • 3n11 – BcChi – Bacillus cereus
    • 3iwr, 2dkv – Chi residues 33-340 – Japanese rice
    • 1edq, 1ctn, 4axn - SmChi – Serratia marcescens
    • 1x6l, 1rd6 – SmChi (mutant)
    • 3g6l - BoChi residues 21-426 – Bionectria ochroleuca
    • 3oa5, 4dws – Chi – Yersinia entomophaga
    • 3w4r – Chi – corn borer
  • Chitinase I binary complex
  • Chitinase II
  • Chitinase II binary complex
  • Chitinase III
    • 2dbt, 1wvu – SgChi residues 30-294 – Streptomyces griseus
    • 1wvv - SgChi residues 30-294 (mutant)
    • 2d49 – SgChi chitin-binding domain - NMR
    • 2xvp – AfChi
    • 2xtk – AfChi + inhibitor
  • Chitinase IV
  • Chitinase V
    • 3alf – tChi residues 26-377 – tobacco
  • Chitinase V binary complex
  • Chitinase VIII
    • 2cjl - Chi residues 41-244 – Streptomyces coelicolor
  • Chitinase XVIII
    • 3sim – Chi – Crocus vernus
  • Chitinase C
    • 4dyg – RyChiC + NAG – Rye
    • 4dwx - RyChiC
    • 4j0l – RyChiC + GlcNAC
  • Other chitinases
    • 1wno, 1w9p - AfChi
    • 2dsk - PfChi catalytic domain – Pyrococcus furiosus
    • 3afb - PfChi catalytic domain (mutant)
    • 1cns – Chi – Hordeum vulgare
    • 2czn - PfChi chitin-binding domain – NMR
    • 2cwr - PfChi chitin-binding domain
    • 3ian – Chi (mutant) – Lactococcus lactis
    • 3fxy - hChi catalytic domain
    • 1lq0 - hChi residues 22-286
    • 1guv - hChi residues 22-387
    • 3fnd, 3co4 – Chi – Bacteroides thetaiotamicron
    • 3cql – Chi – Carica papaya
    • 2z37 - BjChi catalytic domain – Brassica juncea
    • 2z39 – BjChi catalytic domain (mutant)
    • 2uy2 – yChi residues 22-315 – yeast
    • 4hmc – MmChi 60 – Moritella marina
    • 3w3e – Chi – cowpea
    • 3w6b – RaChi catalytic domain – Ralstonia
    • 3w6e – RaChi catalytic domain (mutant)
  • Other chitinases binary complex
    • 3a4w, 3a4x – PfChi catalytic domain (mutant) + NAG
    • 1lg1 - hChi residues 22-387 + chitobiose
    • 1lg2 - hChi residues 22-387 + ethylene glycol
    • 3fy1, 2ybt, 2ybu - hChi catalytic domain + inhibitor
    • 1hki, 1hkj - hChi + inhibitor
    • 2z38 - BjChi catalytic domain + Cl
    • 2uy3, 2uy4, 2uy5 - yChi residues 22-315 + inhibitor
    • 1w9v, 1w9u - AfChi + polypeptide
    • 4hmd – MmChi 60 + intermediate
    • 4hme – MmChi 60 + NAG
    • 3w6c – RaChi catalytic domain + disaccharide
    • 3w6d, 3w6f – RaChi catalytic domain (mutant) + polysaccharide

}}

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