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Cyclin

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{{STRUCTURE_1vin| PDB=1vin | SIZE=300| SCENE=Cyclin/Cv/1 |right|CAPTION=Cyclin A3 [[1vin]] }}
{{STRUCTURE_1vin| PDB=1vin | SIZE=300| SCENE=Cyclin/Cv/1 |right|CAPTION=Cyclin A3 [[1vin]] }}
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===CYCA2===
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*CYCA2
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[[3my5]], [[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[3dog]], [[3ddp]], [[3ddq]], [[3bht]], [[2v22]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[2bpm]], [[2c4g]], [[1fvv]], [[2c6t]] – hCYCA2 +CDK2+inhibitor - human<br />
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**[[3my5]], [[2wpa]], [[2wxv]], [[2wih]], [[2wip]], [[3f5x]], [[3eoc]], [[3eid]], [[3ej1]], [[3dog]], [[3ddp]], [[3ddq]], [[3bht]], [[2v22]], [[2uue]], [[2i40]], [[2bkz]], [[2c5n]], [[2c5o]], [[2c5v]], [[2c5x]], [[2c5y]], [[2bpm]], [[2c4g]], [[1fvv]], [[2c6t]] – hCYCA2 +CDK2+inhibitor - human<br />
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[[3bhu]], [[3bhv]], [[2uzd]], [[2uzb]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2iw6]], [[2iw8]], [[2iw9]], [[2g9x]], [[1oi9]], [[1oiu]], [[1oiy]], [[1ogu]], [[1p5e]], [[1pkd]], [[1h1p]], [[1h1q]], [[1h1r]], [[1h1s]] - hCYCA2 +CDK2 T160P+inhibitor<br />
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**[[3bhu]], [[3bhv]], [[2uzd]], [[2uzb]], [[2uze]], [[2uzl]], [[2uzn]], [[2uzo]], [[2iw6]], [[2iw8]], [[2iw9]], [[2g9x]], [[1oi9]], [[1oiu]], [[1oiy]], [[1ogu]], [[1p5e]], [[1pkd]], [[1h1p]], [[1h1q]], [[1h1r]], [[1h1s]] - hCYCA2 +CDK2 T160P+inhibitor<br />
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[[1fin]] - hCYCA2 +CDK2<br />
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**[[1fin]] - hCYCA2 +CDK2<br />
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[[1vyw]] - hCYCA2 C-terminal + hCDK2<br />
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**[[1vyw]] - hCYCA2 C-terminal + hCDK2<br />
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[[1jst]], [[3tnw]] - hCYCA2 +CDK2 T160P<br />
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**[[1jst]], [[3tnw]] - hCYCA2 +CDK2 T160P<br />
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[[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]] - hCYCA2 +CDK2 T160P+peptide<br />
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**[[1h24]], [[1h25]], [[1h26]], [[1h27]], [[1h28]], [[1gy3]] - hCYCA2 +CDK2 T160P+peptide<br />
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[[4bck]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfn]], [[4cfw]] - hCYCA2 +CDK2 T160P + inhibitor<br />
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**[[4bck]], [[4bcm]], [[4bcn]], [[4bco]], [[4bcp]], [[4bcq]], [[4cfn]], [[4cfw]] - hCYCA2 +CDK2 T160P + inhibitor<br />
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[[4fx3]] - hCYCA2 +CDK2 + inhibitor<br />
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**[[4fx3]] - hCYCA2 +CDK2 + inhibitor<br />
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[[4eoi]], [[4eoj]], [[4eok]], [[4eol]], [[4eom]], [[4eon]], [[4eoo]], [[4eop]], [[4eoq]], [[4eor]], [[4eos]] - hCYCA2 C-terminal +CDK2 T160P + inhibitor<br />
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**[[4eoi]], [[4eoj]], [[4eok]], [[4eol]], [[4eom]], [[4eon]], [[4eoo]], [[4eop]], [[4eoq]], [[4eor]], [[4eos]] - hCYCA2 C-terminal +CDK2 T160P + inhibitor<br />
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[[2cjm]] - hCYCA2 +CDK2 T160P Y15P<br />
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**[[2cjm]] - hCYCA2 +CDK2 T160P Y15P<br />
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[[2cch]] - hCYCA2 +CDK2 T160P+ATP analog<br />
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**[[2cch]] - hCYCA2 +CDK2 T160P+ATP analog<br />
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[[4i3z]], [[4ii5]] - hCYCA2 +CDK2 T160P+ADP + Mg<br />
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**[[4i3z]], [[4ii5]] - hCYCA2 +CDK2 T160P+ADP + Mg<br />
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[[2cci]] - hCYCA2 +CDK2 T160P+CDC homolog<br />
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**[[2cci]] - hCYCA2 +CDK2 T160P+CDC homolog<br />
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[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1qmz]], [[3qhw]] - hCYCA2 +CDK2+peptide<br />
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**[[2wma]], [[2wmb]], [[2x1n]], [[2wev]], [[2wfy]], [[2whb]], [[1okv]], [[1okw]], [[1ol1]], [[1ol2]], [[1urc]], [[1qmz]], [[3qhw]] - hCYCA2 +CDK2+peptide<br />
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[[1jsu]] - hCYCA2 +CDK2 (mutant)+P27<br />
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**[[1jsu]] - hCYCA2 +CDK2 (mutant)+P27<br />
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[[3qhr]], [[3khw]] - CYCA2 + P33 protein kinase + CDK2 peptide – mouse
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**[[3qhr]], [[3khw]] - CYCA2 + P33 protein kinase + CDK2 peptide – mouse
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===CYCA3===
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*CYCA3
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[[1vin]] – CYCA3 - bovine<br />
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**[[1vin]] – CYCA3 - bovine<br />
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[[1e9h]] – hCYCA3 +CDK2 T160P+inhibitor<br />
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**[[1e9h]] – hCYCA3 +CDK2 T160P+inhibitor<br />
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===CYCB1===
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*CYCB1
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[[2b9r]] – hCYCB1 (mutant)<br />
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**[[2b9r]] – hCYCB1 (mutant)<br />
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[[2jgz]] - hCYCB1 +CDK2
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**[[2jgz]] - hCYCB1 +CDK2
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===CYCC===
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*CYCC
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[[3rgf]], [[4g6l]] – hCYCC + CDK8<br />
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**[[3rgf]], [[4g6l]] – hCYCC + CDK8<br />
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[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]] – hCYCC + CDK8 + inhibitor<br />
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**[[4f6s]], [[4f6u]], [[4f6w]], [[4f70]], [[4f7j]], [[4f7l]], [[4f7n]], [[4f7s]] – hCYCC + CDK8 + inhibitor<br />
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===CYCD===
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*CYCD
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[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] - hCYCD1 +CDK4 (mutant)<br />
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**[[2w96]], [[2w99]], [[2w9f]], [[2w9z]] - hCYCD1 +CDK4 (mutant)<br />
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[[3g33]] – hCYCD3 +CDK4
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**[[3g33]] – hCYCD3 +CDK4
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===CYCE===
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*CYCE
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[[1w98]] – hCYCE1 +CDK2 T160P
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**[[1w98]] – hCYCE1 +CDK2 T160P
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===CYCH===
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*CYCH
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[[1kxu]], [[1jkw]] – hCYCH
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**[[1kxu]], [[1jkw]] – hCYCH
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===CYCK===
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*CYCK
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[[2i53]] – hCYCK N-terminal<br />
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**[[2i53]] – hCYCK N-terminal<br />
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[[4cjy]] - hCYCK +CDK12 T160P+inhibitor<br />
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**[[4cjy]] - hCYCK +CDK12 T160P+inhibitor<br />
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===CYCT===
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*CYCT
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[[3blh]] - hCYCT1 +CDK9<br />
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**[[3blh]] - hCYCT1 +CDK9<br />
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[[3blq]] - hCYCT1 +CDK9+ATP<br />
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**[[3blq]] - hCYCT1 +CDK9+ATP<br />
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[[4imy]] - hCYCT1 +CDK9 TPO160 +AMP + AF4/MRF2 family member 4<br />
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**[[4imy]] - hCYCT1 +CDK9 TPO160 +AMP + AF4/MRF2 family member 4<br />
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[[3lq5]], [[3tn8]], [[3tnh]], [[3tni]], [[4bcf]], [[4bcg]], [[4bch]], [[4bci]], [[4bcj]] – hCYCT1 (mutant)+CDK9<br />
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**[[3lq5]], [[3tn8]], [[3tnh]], [[3tni]], [[4bcf]], [[4bcg]], [[4bch]], [[4bci]], [[4bcj]] – hCYCT1 (mutant)+CDK9<br />
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[[3blr]] - hCYCT1 +CDK9+inhibitor<br />
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**[[3blr]] - hCYCT1 +CDK9+inhibitor<br />
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[[3my1]], [[4ec8]], [[4ec9]] - hCYCT1 (mutant)+CDK9 TPO160 +inhibitor<br />
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**[[3my1]], [[4ec8]], [[4ec9]] - hCYCT1 (mutant)+CDK9 TPO160 +inhibitor<br />
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[[3mi9]], [[3mia]] - hCYCT1 +CDK9+protein TAT<br />
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**[[3mi9]], [[3mia]] - hCYCT1 +CDK9+protein TAT<br />
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[[2pk2]] - hCYCT1/protein TAT<br />
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**[[2w2h]] - CYCT1 +protein TAT + RNA – horse<br />
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[[2w2h]] - CYCT1 +protein TAT + RNA – horse<br />
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**[[2ivx]] – hCYCT2 (mutant)
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[[2ivx]] – hCYCT2 (mutant)
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===CYC===
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*CYC
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[[2pk9]] – yCYC PHO80 +CDK PHO85 – yeast<br />
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**[[2pk9]] – yCYC PHO80 +CDK PHO85 – yeast<br />
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[[2pmi]] - yCYC PHO80 +CDK PHO85+ATPgS
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**[[2pmi]] - yCYC PHO80 +CDK PHO85+ATPgS
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===Viral CYC===
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*Viral CYC
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[[2euf]], [[2f2c]], [[2xo2]], [[1jow]] – V-CYC viral+hCDK6 – Herpesvirus<br />
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**[[2euf]], [[2f2c]], [[2xo2]], [[1jow]] – V-CYC viral+hCDK6 – Herpesvirus<br />
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[[1bu2]] – V-CYC<br />
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**[[1bu2]] – V-CYC<br />
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[[1xo2]] - V-CYC + hCDK6 + inhibitor<br />
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**[[1xo2]] - V-CYC + hCDK6 + inhibitor<br />
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[[1g3n]] - V-CYC viral+hCDK6+CDK6 inhibitor<br />
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**[[1g3n]] - V-CYC viral+hCDK6+CDK6 inhibitor<br />
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[[1f5q]] - V-CYC g viral+hCDK2
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**[[1f5q]] - V-CYC g viral+hCDK2
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:46, 20 November 2014

Template:STRUCTURE 1vin

Cyclin (CYC) activate CYC-dependent kinase (CDK) thus acting in the control of the cell cycle. The CYC name derives from the fact that their concentration varies during the cell cycle. Among the CYCs, CYCA are active in the S phase, CYCD regulate the transition from G1 to S. See also Intrinsically Disordered Protein.



3D Structures of Cyclin

Updated on 20-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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