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== Beta-2-microglobulin== | == Beta-2-microglobulin== | ||
| - | Beta-2 microglobulin is a structural protein sub-unit of the class I major histocompatibility complex. It has a molecular weight of approximately 12 kDa. In dialysis patients, it has the propensity to form amyloid fibrils in a condition known as dialysis-related amyloidosis (DRA). The oligomerization | + | Beta-2 microglobulin is a structural protein sub-unit of the class I major histocompatibility complex. It has a molecular weight of approximately 12 kDa. In dialysis patients, it has the propensity to form amyloid fibrils in a condition known as dialysis-related amyloidosis (DRA). The mechanism of oligomerization and eventual fibrillation are of particular interest to the Vachet Research Group at the University of Massachusetts-Amherst. |
== Disease == | == Disease == | ||
Revision as of 16:57, 20 November 2014
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Contents |
Beta-2-microglobulin
Beta-2 microglobulin is a structural protein sub-unit of the class I major histocompatibility complex. It has a molecular weight of approximately 12 kDa. In dialysis patients, it has the propensity to form amyloid fibrils in a condition known as dialysis-related amyloidosis (DRA). The mechanism of oligomerization and eventual fibrillation are of particular interest to the Vachet Research Group at the University of Massachusetts-Amherst.
Disease
Aggregation Mechanism
Display Nick's Dimer, try to find the tetramer, and the hexameter
B2m Mutations
Structural effects of the various mutations and their oligomers
Code to color a green scene
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>
Useful Links
The Vachet Lab [1]
