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Deaminase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Cytidine deaminase===
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*Cytidine deaminase
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[[1r5t]] – yCDA - yeast <BR />
+
**[[1r5t]] – yCDA - yeast <BR />
-
[[2a8n]] – AtCDA – ''Agrobacterium tumefaciens'' <BR />
+
**[[2a8n]] – AtCDA – ''Agrobacterium tumefaciens'' <BR />
-
[[2g84]] – CDA – ''Nitrosomonas europaea'' <BR />
+
**[[2g84]] – CDA – ''Nitrosomonas europaea'' <BR />
-
[[2d30]] – CDA – ''Bacillus anthracis'' <BR />
+
**[[2d30]] – CDA – ''Bacillus anthracis'' <BR />
-
[[3dmo]] – CDA – ''Burkholderia pseudomallei'' <BR />
+
**[[3dmo]] – CDA – ''Burkholderia pseudomallei'' <BR />
-
[[3ijf]] – MtCDA – ''Mycobacterium tuberculosis'' <BR />
+
**[[3ijf]] – MtCDA – ''Mycobacterium tuberculosis'' <BR />
-
[[3mpz]] – CDA – ''Mycobacterium smegmatis'' <BR />
+
**[[3mpz]] – CDA – ''Mycobacterium smegmatis'' <BR />
-
[[3r2n]] – CDA – ''Mycobacterium leprae'' <BR />
+
**[[3r2n]] – CDA – ''Mycobacterium leprae'' <BR />
-
[[4f3w]] – CDA – ''Mycobacterium marinum'' <BR />
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**[[4f3w]] – CDA – ''Mycobacterium marinum'' <BR />
-
''Cytidine deaminase complex with nucleoside''
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*''Cytidine deaminase complex with nucleoside''
-
[[1ctt]] – EcCDA + dihydro-pyrimidinone – ''Escherichia coli'' <BR />
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**[[1ctt]] – EcCDA + dihydro-pyrimidinone – ''Escherichia coli'' <BR />
-
[[1ctu]] – EcCDA + hydroxyl-dihydro-zebularine <BR />
+
**[[1ctu]] – EcCDA + hydroxyl-dihydro-zebularine <BR />
-
[[1af2]] – EcCDA + uridine <BR />
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**[[1af2]] – EcCDA + uridine <BR />
-
[[1aln]] – EcCDA + deazacytidine <BR />
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**[[1aln]] – EcCDA + deazacytidine <BR />
-
[[1jtk]] – BsCDA + tetrahydrodeoxyuridine - ''Bacillus subtilis'' <BR />
+
**[[1jtk]] – BsCDA + tetrahydrodeoxyuridine - ''Bacillus subtilis'' <BR />
-
[[1uwz]], [[1ux0]], [[1ux1]] – BsCDA (mutant) + tetrahydrodeoxyuridine <BR />
+
**[[1uwz]], [[1ux0]], [[1ux1]] – BsCDA (mutant) + tetrahydrodeoxyuridine <BR />
-
[[1mq0]] – hCDA + β-ribofuranosyl diazepinone - human <BR />
+
**[[1mq0]] – hCDA + β-ribofuranosyl diazepinone - human <BR />
-
[[1zab]] – mCDA + deazauridine - mouse <BR />
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**[[1zab]] – mCDA + deazauridine - mouse <BR />
-
[[2fr5]] – mCDA + tetrahydrouridine <BR />
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**[[2fr5]] – mCDA + tetrahydrouridine <BR />
-
[[2fr6]] – mCDA + cytidine + uridine <BR />
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**[[2fr6]] – mCDA + cytidine + uridine <BR />
-
[[4eg2]] – CDA + uridine - ''Vibrio cholerae'' <BR />
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**[[4eg2]] – CDA + uridine - ''Vibrio cholerae'' <BR />
-
===Cytosine deaminase===
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*Cytosine deaminase
-
[[1k6w]] – EcCDDA <BR />
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**[[1k6w]] – EcCDDA <BR />
-
[[1r9x]], [[1r9y]], [[1r9z]], [[1ra0]], [[1ra5]], [[3g77]] – EcCDDA (mutant)<BR />
+
**[[1r9x]], [[1r9y]], [[1r9z]], [[1ra0]], [[1ra5]], [[3g77]] – EcCDDA (mutant)<BR />
-
[[1rb7]], [[1uaq]] – yCDDA <BR />
+
**[[1rb7]], [[1uaq]] – yCDDA <BR />
-
[[1ysb]], [[1ysd]] – yCDDA (mutant)<BR />
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**[[1ysb]], [[1ysd]] – yCDDA (mutant)<BR />
-
''Cytosine deaminase complex''
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*''Cytosine deaminase complex''
-
[[3r0d]] – EcCDDA + Zn <BR />
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**[[3r0d]] – EcCDDA + Zn <BR />
-
[[3rn6]] – EcCDDA + Zn + iso-guanine<BR />
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**[[3rn6]] – EcCDDA + Zn + iso-guanine<BR />
-
[[1k70]] – EcCDDA + pyrimidine derivative<BR />
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**[[1k70]] – EcCDDA + pyrimidine derivative<BR />
-
[[1rak]] – EcCDDA (mutant) + pyrimidine derivative<BR />
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**[[1rak]] – EcCDDA (mutant) + pyrimidine derivative<BR />
-
[[3o7u]] – EcCDDA + Zn + phosphono-cytosine<BR />
+
**[[3o7u]] – EcCDDA + Zn + phosphono-cytosine<BR />
-
[[1ox7]] – yCDDA + Zn <BR />
+
**[[1ox7]] – yCDDA + Zn <BR />
-
[[1p6o]] – yCDDA + pyrimidine derivative<BR />
+
**[[1p6o]] – yCDDA + pyrimidine derivative<BR />
-
[[2o3k]] – yCDDA (mutant) + pyrimidine derivative<BR />
+
**[[2o3k]] – yCDDA (mutant) + pyrimidine derivative<BR />
-
===Guanine deaminase===
+
*Guanine deaminase
-
[[1tiy]], [[1wkq]] – BsGDA <BR />
+
**[[1tiy]], [[1wkq]] – BsGDA <BR />
-
[[3e0l]] – hGDA<br />
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**[[3e0l]] – hGDA<br />
-
''Guanine deaminase complex with nucleoside''
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*''Guanine deaminase complex with nucleoside''
-
[[2i9u]] – GDA + guanine – ''Clostridium acetobutylicum'' <BR />
+
**[[2i9u]] – GDA + guanine – ''Clostridium acetobutylicum'' <BR />
-
[[2ood]] – GDA + guanine – ''Bradrhizobium japonicum'' <BR />
+
**[[2ood]] – GDA + guanine – ''Bradrhizobium japonicum'' <BR />
-
[[2uz9]] – hGDA + xanthine <BR />
+
**[[2uz9]] – hGDA + xanthine <BR />
-
[[4aql]] – hGDA + valacyclovir <BR />
+
**[[4aql]] – hGDA + valacyclovir <BR />
-
===Adenine deaminase===
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*Adenine deaminase
-
[[2ics]] – ADA - ''Enterococcus faecalis''<BR />
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**[[2ics]] – ADA - ''Enterococcus faecalis''<BR />
-
[[3nqb]], [[3t81]], [[3t8l]] – AtADA <BR />
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**[[3nqb]], [[3t81]], [[3t8l]] – AtADA <BR />
-
===Adenosine deaminase===
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*Adenosine deaminase See [[Adenosine deaminase]]
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See [[Adenosine deaminase]]
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*Glucosamine 6-phosphate deaminase
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===Glucosamine 6-phosphate deaminase===
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**[[1dea]], [[1cd5]], [[1fs6]], [[1fsf]] – EcGPD <BR />
 +
**[[1jt9]] – EcGPD (mutant) <BR />
 +
**[[2ri0]] – SmGPD – ''Streptococcus mutans'' <BR />
 +
**[[3hns]] – GPD – ''Borrelia burgdorferi''<br />
 +
**[[1hor]] – EcGPD + deoxy-amino glucitol-phosphate<BR />
 +
**[[1hot]], [[1frz]], [[1fs5]], [[2wu1]] – EcGPD + N-acetyl-glucosamine-6-phosphate<BR />
 +
**[[1fqo]] – EcGPD + fructose 6-phosphate<BR />
 +
**[[2ri1]] – SmGPD + glucosamine-6-phosphate<BR />
-
[[1dea]], [[1cd5]], [[1fs6]], [[1fsf]] – EcGPD <BR />
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*1-aminocyclopropane-1-carboxylate (ACC) deaminase
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[[1jt9]] – EcGPD (mutant) <BR />
+
-
[[2ri0]] – SmGPD – ''Streptococcus mutans'' <BR />
+
-
[[3hns]] – GPD – ''Borrelia burgdorferi''<br />
+
-
[[1hor]] – EcGPD + deoxy-amino glucitol-phosphate<BR />
+
-
[[1hot]], [[1frz]], [[1fs5]], [[2wu1]] – EcGPD + N-acetyl-glucosamine-6-phosphate<BR />
+
-
[[1fqo]] – EcGPD + fructose 6-phosphate<BR />
+
-
[[2ri1]] – SmGPD + glucosamine-6-phosphate<BR />
+
-
===1-aminocyclopropane-1-carboxylate (ACC) deaminase===
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**[[1f2d]] – WsACCD + PLP – ''Williopsis saturnus''<BR />
 +
**[[1j0c]] – WsACCD (mutant) + PLP <BR />
 +
**[[1j0d]] – WsACCD (mutant) + inhibitor<BR />
 +
**[[1j0e]] – WsACCD (mutant) + PLP + ACC<BR />
 +
**[[1j0a]] – PhACCD + PLP + 2-propanol – ''Pyrococcus horikoshii''<BR />
 +
**[[1j0b]] – PhACCD + inhibitor<BR />
 +
**[[1tyz]] – PsACCD + PLP - ''Pseudomonas''<BR />
 +
**[[1rqx]] – PsACCD + PLP + inhibitor <BR />
 +
**[[1tz2]] – PsACCD + PLP + ACC<BR />
 +
**[[1tzj]] – PsACCD + PLP + vinylglycine<BR />
 +
**[[1tzk]] – PsACCD + PLP + α-ketobutyrate<BR />
 +
**[[1tzm]] – PsACCD + PLP + chloroalanine<BR />
-
[[1f2d]] – WsACCD + PLP – ''Williopsis saturnus''<BR />
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*dCTP deaminase
-
[[1j0c]] – WsACCD (mutant) + PLP <BR />
+
-
[[1j0d]] – WsACCD (mutant) + inhibitor<BR />
+
-
[[1j0e]] – WsACCD (mutant) + PLP + ACC<BR />
+
-
[[1j0a]] – PhACCD + PLP + 2-propanol – ''Pyrococcus horikoshii''<BR />
+
-
[[1j0b]] – PhACCD + inhibitor<BR />
+
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[[1tyz]] – PsACCD + PLP - ''Pseudomonas''<BR />
+
-
[[1rqx]] – PsACCD + PLP + inhibitor <BR />
+
-
[[1tz2]] – PsACCD + PLP + ACC<BR />
+
-
[[1tzj]] – PsACCD + PLP + vinylglycine<BR />
+
-
[[1tzk]] – PsACCD + PLP + α-ketobutyrate<BR />
+
-
[[1tzm]] – PsACCD + PLP + chloroalanine<BR />
+
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===dCTP deaminase===
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**[[2qlp]] – MtCTPD <BR />
 +
**[[3km3]] – CTPD – ''Anaplasma phagocytophilum''<br />
 +
**[[4dhk]] – CTPD - ''Burkholderia thailandensis''<BR />
-
[[2qlp]] – MtCTPD <BR />
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*''dCTP deaminase complex''
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[[3km3]] – CTPD – ''Anaplasma phagocytophilum''<br />
+
-
[[4dhk]] – CTPD - ''Burkholderia thailandensis''<BR />
+
-
''dCTP deaminase complex''
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**[[1xs1]] – EcCTPD + dUTP<BR />
 +
**[[1xs4]] – EcCTPD (mutant) + dCTP<BR />
 +
**[[2j4h]] – EcCTPD (mutant) + dCDP<BR />
 +
**[[1xs6]], [[2v9x]] – EcCTPD (mutant) + dUTP<BR />
 +
**[[2j4q]] – EcCTPD (mutant) + dTTP + dTDP<BR />
 +
**[[2qxx]] – MtCTPD + dTTP<BR />
-
[[1xs1]] – EcCTPD + dUTP<BR />
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*dCTP deaminase-dUTPase
-
[[1xs4]] – EcCTPD (mutant) + dCTP<BR />
+
-
[[2j4h]] – EcCTPD (mutant) + dCDP<BR />
+
-
[[1xs6]], [[2v9x]] – EcCTPD (mutant) + dUTP<BR />
+
-
[[2j4q]] – EcCTPD (mutant) + dTTP + dTDP<BR />
+
-
[[2qxx]] – MtCTPD + dTTP<BR />
+
-
===dCTP deaminase-dUTPase===
+
**[[2hxb]], [[1ogh]], [[1pkh]], [[3gf0]] – MjDCD-DUT – ''Methanocaldococcus jannaschii'' <BR />
 +
**[[1pkj]] – MjDCD-DUT + dUTP<BR />
 +
**[[2hxd]] – MjDCD-DUT (mutant) + dUTP derivative<BR />
 +
**[[1pkk]] – MjDCD-DUT + dCTP<BR />
-
[[2hxb]], [[1ogh]], [[1pkh]], [[3gf0]] – MjDCD-DUT – ''Methanocaldococcus jannaschii'' <BR />
+
*Porphobilinogen deaminase See [[Porphobilinogen Deaminase]]
-
[[1pkj]] – MjDCD-DUT + dUTP<BR />
+
-
[[2hxd]] – MjDCD-DUT (mutant) + dUTP derivative<BR />
+
-
[[1pkk]] – MjDCD-DUT + dCTP<BR />
+
-
===Porphobilinogen deaminase===
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*Blasticidin-S deaminase
-
See [[Porphobilinogen Deaminase]]
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**[[1wn5]], [[2z3g]] – AtBSD – ''Aspergillus terreus'' <BR />
 +
**[[2z3j]] – AtBSD (mutant) <BR />
 +
**[[3oj6]] – BSD – Coccidioides immitis <BR />
 +
**[[1wn6]] – AtBSD + blasticidin-S intermediate<BR />
 +
**[[2z3h]] – AtBSD + deaminohydroxy blasticidin-S <BR />
 +
**[[2z3i]] – AtBSD (mutant) + blasticidin-S <BR />
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===Blasticidin-S deaminase===
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*Threonine deaminase
-
[[1wn5]], [[2z3g]] – AtBSD – ''Aspergillus terreus'' <BR />
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**[[1tdj]] – EcTHD + PLP <BR />
-
[[2z3j]] – AtBSD (mutant) <BR />
+
**[[2gn0]], [[2gn1]] – StTHD + PLP derivative – ''Salmonella typhimurium''<BR />
-
[[3oj6]] – BSD – Coccidioides immitis <BR />
+
**[[2gn2]] – StTHD + PLP derivative + CMP<BR />
-
[[1wn6]] – AtBSD + blasticidin-S intermediate<BR />
+
**[[3iau]] – THD + PLP derivative – tomato<BR />
-
[[2z3h]] – AtBSD + deaminohydroxy blasticidin-S <BR />
+
-
[[2z3i]] – AtBSD (mutant) + blasticidin-S <BR />
+
-
===Threonine deaminase===
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*L-serine deaminase
-
[[1tdj]] – EcTHD + PLP <BR />
+
**[[1pwe]] – rLSD - rat <BR />
-
[[2gn0]], [[2gn1]] – StTHD + PLP derivative – ''Salmonella typhimurium''<BR />
+
**[[1p5j]], [[2rkb]] – hLSD (mutant) + PLP <BR />
-
[[2gn2]] – StTHD + PLP derivative + CMP<BR />
+
**[[1pwh]] – rLSD + PLP derivative <BR />
-
[[3iau]] – THD + PLP derivative – tomato<BR />
+
-
===L-serine deaminase===
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*D-serine deaminase
-
 
+
-
[[1pwe]] – rLSD - rat <BR />
+
-
[[1p5j]], [[2rkb]] – hLSD (mutant) + PLP <BR />
+
-
[[1pwh]] – rLSD + PLP derivative <BR />
+
-
 
+
-
===D-serine deaminase===
+
-
 
+
-
[[3r0x]], [[3r0z]] – DSD – ''Salmonella enterica''<BR />
+
-
[[3ss7]], [[3ss9]] – EcDSD + PLP <BR />
+
 +
**[[3r0x]], [[3r0z]] – DSD – ''Salmonella enterica''<BR />
 +
**[[3ss7]], [[3ss9]] – EcDSD + PLP <BR />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:43, 23 November 2014

Structure of cytidine deaminase complex with deazacytosine (PDB entry 1aln)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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