Molecular Playground/CLOCK:BMAL1 heterodimer complex
From Proteopedia
(Difference between revisions)
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==CLOCK== | ==CLOCK== | ||
| + | CLOCK is a protein central to the regulation of the mammalian circadian rhythm system. CLOCK regulates the circadian rhythm by forming heterodimers with other circadian rhythm proteins to activate the transcription of other proteins. | ||
<ref>DOI:10.1126/science.280.5369.1564</ref> | <ref>DOI:10.1126/science.280.5369.1564</ref> | ||
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==Heterodimer complex== | ==Heterodimer complex== | ||
| - | == | + | == Circadian Rhythm == |
<ref>DOI: 10.1126/science.1222804</ref> | <ref>DOI: 10.1126/science.1222804</ref> | ||
== Disease == | == Disease == | ||
Revision as of 04:22, 24 November 2014
CLOCK:BMAL1 heterodimer complex
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References
- ↑ doi: https://dx.doi.org/10.1126/science.280.5369.1564
- ↑ Huang N, Chelliah Y, Shan Y, Taylor CA, Yoo SH, Partch C, Green CB, Zhang H, Takahashi JS. Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex. Science. 2012 Jul 13;337(6091):189-94. Epub 2012 May 31. PMID:22653727 doi:10.1126/science.1222804
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