Lysin

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==egg lysin ==
==egg lysin ==
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''><scene name='60/607850/Alpha_helixes/1'>push here to see Lysine structure</scene>
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<scene name='60/607850/Lysin_fertilization_protein/2'>egg lysine structure</scene>
== Function ==
== Function ==

Revision as of 07:37, 24 November 2014

Contents

egg lysin

Function

Egg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.


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Structural highlights

The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic molecule. you can see the alpha helixes in pink. exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of ,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action.


</StructureSection>

References

The crystal structure of lysin, a fertilization protein. Shaw A1, McRee DE, Vacquier VD, Stout CD.

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