DNA polymerase

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{{STRUCTURE_1taq| PDB=1taq | SIZE=350| SCENE=DNA_polymerase/Cv/1 |right|CAPTION=DNA polymerase complex with octylglucoside [[1taq]] }}
{{STRUCTURE_1taq| PDB=1taq | SIZE=350| SCENE=DNA_polymerase/Cv/1 |right|CAPTION=DNA polymerase complex with octylglucoside [[1taq]] }}
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Family A – replicative and repair Dpo===
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*Family A – replicative and repair Dpo
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[[2ajq]] – T7Dpo (mutant) + thioredoxin (mutant) + DNA - Enterobacteria phage T7<br />
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**[[2ajq]] – T7Dpo (mutant) + thioredoxin (mutant) + DNA - Enterobacteria phage T7<br />
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[[1t7p]] - T7Dpo (mutant) + thioredoxin + DNA<br />
+
**[[1t7p]] - T7Dpo (mutant) + thioredoxin + DNA<br />
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[[1zyq]], [[1x9m]], [[1x9s]], [[1x9w]], [[1tk0]], [[1skr]], [[1sks]], [[1skw]], [[1sl0]], [[1sl1]], [[1sl2]], [[1t7p]] - T7Dpo (mutant) + thioredoxin + DNA + nucleotide<br />
+
**[[1zyq]], [[1x9m]], [[1x9s]], [[1x9w]], [[1tk0]], [[1skr]], [[1sks]], [[1skw]], [[1sl0]], [[1sl1]], [[1sl2]], [[1t7p]] - T7Dpo (mutant) + thioredoxin + DNA + nucleotide<br />
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[[1t8e]], [[1tk5]], [[1tk8]], [[1tkd]] - T7Dpo + thioredoxin + DNA + nucleotide<br />
+
**[[1t8e]], [[1tk5]], [[1tk8]], [[1tkd]] - T7Dpo + thioredoxin + DNA + nucleotide<br />
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[[4i9l]] – RB69Dpo (mutant) – Enterobacteria phage RB69<br />
+
**[[4i9l]] – RB69Dpo (mutant) – Enterobacteria phage RB69<br />
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[[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]] – RB69Dpo (mutant) + DNA<br />
+
**[[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]] – RB69Dpo (mutant) + DNA<br />
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[[2gv9]] – Dpo – ''Herpes simplex'' virus<br />
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**[[2gv9]] – Dpo – ''Herpes simplex'' virus<br />
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[[2kzz]], [[1d8y]], [[2kzm]] – EcDpo I klenow fragment - ''Escherichia coli''<br />
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**[[2kzz]], [[1d8y]], [[2kzm]] – EcDpo I klenow fragment - ''Escherichia coli''<br />
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[[1qsl]] - EcDpo I klenow fragment + DNA<br />
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**[[1qsl]] - EcDpo I klenow fragment + DNA<br />
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[[1kfs]], [[1krp]], [[1ksp]], [[1kln]] - EcDpo I klenow fragment (mutant) + DNA<br />
+
**[[1kfs]], [[1krp]], [[1ksp]], [[1kln]] - EcDpo I klenow fragment (mutant) + DNA<br />
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[[1kfd]], [[1dpi]] - EcDpo I klenow fragment + nucleotide<br />
+
**[[1kfd]], [[1dpi]] - EcDpo I klenow fragment + nucleotide<br />
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[[1d9d]], [[1d9f]], [[2kfn]] - EcDpo I klenow fragment + DNA + nucleotide<br />
+
**[[1d9d]], [[1d9f]], [[2kfn]] - EcDpo I klenow fragment + DNA + nucleotide<br />
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[[2kfz]] - EcDpo I klenow fragment (mutant) + DNA + nucleotide<br />
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**[[2kfz]] - EcDpo I klenow fragment (mutant) + DNA + nucleotide<br />
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[[1taq]] – TaDpo I - ''Thermus aquaticus''<br />
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**[[1taq]] – TaDpo I - ''Thermus aquaticus''<br />
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[[1jxe]] – TaDpo I Stoffel fragment<br />
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**[[1jxe]] – TaDpo I Stoffel fragment<br />
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[[1ktq]] - TaDpo I klenow fragment<br />
+
**[[1ktq]] - TaDpo I klenow fragment<br />
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[[5ktq]] – TaDpo I + nucleotide<br />
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**[[5ktq]] – TaDpo I + nucleotide<br />
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[[3ojs]], [[3oju]], [[1tau]], [[4dle]], [[4dlg]], [[4elt]], [[4elu]], [[4elv]] - TaDpo I + DNA<br />
+
**[[3ojs]], [[3oju]], [[1tau]], [[4dle]], [[4dlg]], [[4elt]], [[4elu]], [[4elv]] - TaDpo I + DNA<br />
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[[3po4]], [[3po5]], [[3rtv]], [[3sv3]], [[3sv4]], [[3syz]], [[3sz2]], [[4c8k]], [[4c8l]], [[4c8m]], [[4c8n]], [[4c8o]], [[4cch]] - TaDpo I klenow fragment + DNA<br />
+
**[[3po4]], [[3po5]], [[3rtv]], [[3sv3]], [[3sv4]], [[3syz]], [[3sz2]], [[4c8k]], [[4c8l]], [[4c8m]], [[4c8n]], [[4c8o]], [[4cch]] - TaDpo I klenow fragment + DNA<br />
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[[4bwm]], [[4bwj]] - TaDpo I klenow fragment + DNA + RNA<br />
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**[[4bwm]], [[4bwj]] - TaDpo I klenow fragment + DNA + RNA<br />
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[[3py8]] - TaDpo I klenow fragment (mutant) + DNA<br />
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**[[3py8]] - TaDpo I klenow fragment (mutant) + DNA<br />
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[[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]], [[3rr7]], [[3rr8]], [[3rrg]], [[3rrh]], [[3t3f]], [[4df4]], [[4df8]], [[4dfj]], [[4dfk]], [[4dfm]], [[4dfp]]- TaDpo I klenow fragment + DNA + nucleotide<br />
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**[[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]], [[3rr7]], [[3rr8]], [[3rrg]], [[3rrh]], [[3t3f]], [[4df4]], [[4df8]], [[4dfj]], [[4dfk]], [[4dfm]], [[4dfp]]- TaDpo I klenow fragment + DNA + nucleotide<br />
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[[1xwl]] - GsDpo I fragment - ''Geobacillus stearothermophilus''<br />
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**[[1xwl]] - GsDpo I fragment - ''Geobacillus stearothermophilus''<br />
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[[2xo7]], [[3hp6]], [[3hpo]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[1xc9]], [[1ua0]], [[1ua1]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1l3s]], [[2bdp]], [[4bdp]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]], [[4b9l]], [[4b9m]], [[4b9n]], [[4b9s]], [[4b9t]], [[4b9u]], [[4b9v]] - GsDpo I fragment + DNA<br />
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**[[2xo7]], [[3hp6]], [[3hpo]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[1xc9]], [[1ua0]], [[1ua1]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1l3s]], [[2bdp]], [[4bdp]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]], [[4b9l]], [[4b9m]], [[4b9n]], [[4b9s]], [[4b9t]], [[4b9u]], [[4b9v]] - GsDpo I fragment + DNA<br />
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[[4dsi]], [[4dsj]], [[4dsk]], [[4dsl]], [[4dwi]] - GsDpo I fragment (mutant) + DNA<br />
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**[[4dsi]], [[4dsj]], [[4dsk]], [[4dsl]], [[4dwi]] - GsDpo I fragment (mutant) + DNA<br />
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[[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]] - GsDpo I fragment + DNA + nucleotide<br />
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**[[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]] - GsDpo I fragment + DNA + nucleotide<br />
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[[3ti0]] - GsDpo I fragment + DNA + nucleotide - ''Bacillus''<br />
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**[[3ti0]] - GsDpo I fragment + DNA + nucleotide - ''Bacillus''<br />
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[[3ikm]] - hDpo γ1+γ2 - human<br />
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**[[3ikm]] - hDpo γ1+γ2 - human<br />
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[[3ikl]], [[2g4c]] - hDpo γ2<br />
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**[[3ikl]], [[2g4c]] - hDpo γ2<br />
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===Family B – 3’-5’ exonuclease activity (includes eukaryotic α,δ,ε)===
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*Family B – 3’-5’ exonuclease activity (includes eukaryotic α,δ,ε)
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[[1ih7]] – EpDpo - Enterobacteria phage RB69<br />
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**[[1ih7]] – EpDpo - Enterobacteria phage RB69<br />
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[[3cfo]], [[4i9l]] – EpDpo (mutant)<br />
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**[[3cfo]], [[4i9l]] – EpDpo (mutant)<br />
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[[1waf]], [[1waj]] - EpDpo + nucleotide<br />
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**[[1waf]], [[1waj]] - EpDpo + nucleotide<br />
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[[3uiq]], [[4dtj]], [[4dtm]], [[4dtn]], [[4dto]], [[4dtp]], [[4dtr]], [[4dts]], [[4dtu]], [[4dtx]], [[4du1]], [[4du3]], [[4du4]] - EpDpo + DNA<br />
+
**[[3uiq]], [[4dtj]], [[4dtm]], [[4dtn]], [[4dto]], [[4dtp]], [[4dtr]], [[4dts]], [[4dtu]], [[4dtx]], [[4du1]], [[4du3]], [[4du4]] - EpDpo + DNA<br />
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[[3nci]], [[3lds]], [[3l8b]], [[3cq8]],[[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]], [[4e3s]] - EpDpo (mutant) + DNA<br />
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**[[3nci]], [[3lds]], [[3l8b]], [[3cq8]],[[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]], [[4e3s]] - EpDpo (mutant) + DNA<br />
[[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[2ozs]], [[2p5g]], [[2dy4]], [[1q9x]], [[1q9y]], [[1ig9]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]], [[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]] - EpDpo (mutant) + DNA + nucleotide<br />
[[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[2ozs]], [[2p5g]], [[2dy4]], [[1q9x]], [[1q9y]], [[1ig9]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]], [[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]] - EpDpo (mutant) + DNA + nucleotide<br />
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[[1clq]], [[3iuq]] - EpDpo + DNA + nucleotide<br />
+
**[[1clq]], [[3iuq]] - EpDpo + DNA + nucleotide<br />
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[[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]], [[3qei]], [[3qer]], [[3qes]], [[3qet]], [[3qev]], [[3qew]], [[3qex]], [[3qnn]], [[3qno]], [[4fj5]], [[4fj7]], [[4fj8]], [[4fj9]], [[4fjg]], [[4fjh]], [[4fji]], [[4fjj]], [[4fjk]], [[4fjl]], [[4fjm]], [[4fjn]], [[4fjx]], [[4fk0]], [[4fk2]], [[4fk4]] - EpDpo (mutant) + DNA + nucleotide analog<br />
+
**[[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]], [[3qei]], [[3qer]], [[3qes]], [[3qet]], [[3qev]], [[3qew]], [[3qex]], [[3qnn]], [[3qno]], [[4fj5]], [[4fj7]], [[4fj8]], [[4fj9]], [[4fjg]], [[4fjh]], [[4fji]], [[4fjj]], [[4fjk]], [[4fjl]], [[4fjm]], [[4fjn]], [[4fjx]], [[4fk0]], [[4fk2]], [[4fk4]] - EpDpo (mutant) + DNA + nucleotide analog<br />
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[[2atq]] – EpDpo + GP32<br />
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**[[2atq]] – EpDpo + GP32<br />
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[[1noy]] – T4Dpo + DNA - Enterobacteria phage T4<br />
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**[[1noy]] – T4Dpo + DNA - Enterobacteria phage T4<br />
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[[1noz]] – T4Dpo residues 1-388<br />
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**[[1noz]] – T4Dpo residues 1-388<br />
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[[2ex3]] – Dpo (mutant) + DNA terminal protein – Bacillus phage φ29<br />
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**[[2ex3]] – Dpo (mutant) + DNA terminal protein – Bacillus phage φ29<br />
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[[2py5]], [[2pzs]], [[1xhz]], [[1xi1]] – BpDpo (mutant) + DNA <br />
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**[[2py5]], [[2pzs]], [[1xhz]], [[1xi1]] – BpDpo (mutant) + DNA <br />
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[[2pyj]], [[2pyl]] - BpDpo (mutant) + DNA + nucleotide<br />
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**[[2pyj]], [[2pyl]] - BpDpo (mutant) + DNA + nucleotide<br />
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[[1xhx]] - BpDpo (mutant)<br />
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**[[1xhx]] - BpDpo (mutant)<br />
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[[4e2i]] – hDpo α subunit β + large T antigen<br />
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**[[4e2i]] – hDpo α subunit β + large T antigen<br />
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[[4bpx]] - hDpo α catalytic subunit + DNA primase small subunit <br />
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**[[4bpx]] - hDpo α catalytic subunit + DNA primase small subunit <br />
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[[2keb]] - hDpo αB - NMR <br />
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**[[2keb]] - hDpo αB - NMR <br />
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[[1n5g]], [[1k0p]], [[1k18]] - hDpo α zinc finger domain- NMR<br />
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**[[1n5g]], [[1k0p]], [[1k18]] - hDpo α zinc finger domain- NMR<br />
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[[3e0j]] - hDpo δ2+δ3<br />
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**[[3e0j]] - hDpo δ2+δ3<br />
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[[3mr4]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]] - hDpo ε catalytic core + DNA + nucleotide<br />
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**[[3mr4]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]] - hDpo ε catalytic core + DNA + nucleotide<br />
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[[3tq1]], [[4j9k]], [[4j9l]], [[4j9m]], [[4j9n]], [[4j9o]], [[4j9p]], [[4j9q]], [[4j9r]], [[4j9s]] - hDpo η catalytic core + DNA<br />
+
**[[3tq1]], [[4j9k]], [[4j9l]], [[4j9m]], [[4j9n]], [[4j9o]], [[4j9p]], [[4j9q]], [[4j9r]], [[4j9s]] - hDpo η catalytic core + DNA<br />
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[[4dl2]], [[4dl3]], [[4dl4]], [[4dl5]], [[4dl6]], [[4dl7]], [[4eey]] - hDpo η + DNA + nucleotide<br />
+
**[[4dl2]], [[4dl3]], [[4dl4]], [[4dl5]], [[4dl6]], [[4dl7]], [[4eey]] - hDpo η + DNA + nucleotide<br />
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[[3oiq]] - yDpo α + cell division control protein 13 – yeast<br />
+
**[[3oiq]] - yDpo α + cell division control protein 13 – yeast<br />
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[[3flo]], [[3lgb]] - yDpo α subunits A,B<br />
+
**[[3flo]], [[3lgb]] - yDpo α subunits A,B<br />
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[[4b08]], [[4fvm]] - yDpo α subunit A<br />
+
**[[4b08]], [[4fvm]] - yDpo α subunit A<br />
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[[4fxd]], [[4fyd]] - yDpo α subunit A + RNA + DNA<br />
+
**[[4fxd]], [[4fyd]] - yDpo α subunit A + RNA + DNA<br />
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[[3iay]] - yDpo δ catalytic subunit + DNA<br />
+
**[[3iay]] - yDpo δ catalytic subunit + DNA<br />
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[[3oha]], [[3ohb]], [[3mfh]] - yDpo ε (mutant) + DNA<br />
+
**[[3oha]], [[3ohb]], [[3mfh]] - yDpo ε (mutant) + DNA<br />
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[[3mfi]], [[4m8o]] - yDpo ε (mutant) + DNA + nucleotide <br />
+
**[[3mfi]], [[4m8o]] - yDpo ε (mutant) + DNA + nucleotide <br />
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[[2r8j]], [[2r8k]] - yDpo ε catalytic domain + DNA + nucleotide <br />
+
**[[2r8j]], [[2r8k]] - yDpo ε catalytic domain + DNA + nucleotide <br />
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[[2xgp]], [[2xgq]], [[2wtf]] - yDpo ε + DNA<br />
+
**[[2xgp]], [[2xgq]], [[2wtf]] - yDpo ε + DNA<br />
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[[3maq]], [[3k57]], [[3k58]], [[3k59]], [[3k5l]], [[3k5m]] - EcDpo II (mutant) + DNA + nucleotide<br />
+
**[[3maq]], [[3k57]], [[3k58]], [[3k59]], [[3k5l]], [[3k5m]] - EcDpo II (mutant) + DNA + nucleotide<br />
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[[3k5n]] - EcDpo II (mutant) + DNA<br />
+
**[[3k5n]] - EcDpo II (mutant) + DNA<br />
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[[3k5o]], [[1q8i]] - EcDpo II (mutant)<br />
+
**[[3k5o]], [[1q8i]] - EcDpo II (mutant)<br />
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[[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br />
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**[[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br />
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[[2jgu]], [[4ahc]] - PfDpo<br />
+
**[[2jgu]], [[4ahc]] - PfDpo<br />
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[[4ail]] – PfDpo + DNA<br />
+
**[[4ail]] – PfDpo + DNA<br />
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[[1tgo]] - TgDpo – ''Thermococcus gorgonarius''<br />
+
**[[1tgo]] - TgDpo – ''Thermococcus gorgonarius''<br />
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[[2vwj]] – TgDpo (mutant) + DNA <br />
+
**[[2vwj]] – TgDpo (mutant) + DNA <br />
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[[2vwk]] - TgDpo (mutant)<br />
+
**[[2vwk]] - TgDpo (mutant)<br />
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[[2xhb]] - Dpo (mutant) + DNA + ''Thermococcus gorgonarius''<br />
+
**[[2xhb]] - Dpo (mutant) + DNA + ''Thermococcus gorgonarius''<br />
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[[1wn7]], [[1wns]] – TkDpo B - ''Thermococcus kodakarensis''<br />
+
**[[1wn7]], [[1wns]] – TkDpo B - ''Thermococcus kodakarensis''<br />
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[[4k8z]] - TkDpo (mutant) + DNA<br />
+
**[[4k8z]] - TkDpo (mutant) + DNA<br />
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[[1qht]] - ThDpo (mutant) – ''Thermococcus''<br />
+
**[[1qht]] - ThDpo (mutant) – ''Thermococcus''<br />
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[[4k8x]] - ThDpo (mutant) + DNA<br />
+
**[[4k8x]] - ThDpo (mutant) + DNA<br />
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[[1d5a]] – DeDpo – ''Desulfurococcus''<br />
+
**[[1d5a]] – DeDpo – ''Desulfurococcus''<br />
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[[4flt]], [[4flu]], [[4flv]], [[4flw]], [[4flx]], [[4fly]], [[4flz]], [[4fm0]], [[4fm1]], [[4fm2]] – Dpo + DNA – ''Pyrococcus abyssi''
+
**[[4flt]], [[4flu]], [[4flv]], [[4flw]], [[4flx]], [[4fly]], [[4flz]], [[4fm0]], [[4fm1]], [[4fm2]] – Dpo + DNA – ''Pyrococcus abyssi''
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+
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===Family C – bacterial chromosomal replicative Dpo (Pol III)===
+
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[[2hnh]], [[2hqa]] - EcDpo III subunit α catalytic fragment<br />
+
*Family C – bacterial chromosomal replicative Dpo (Pol III)
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[[4jom]] - EcDpo III α subunit (mutant)<br />
+
-
[[2hpi]], [[2hpm]] - TaDpo III α subunit<br />
+
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[[3e0d]] - TaDpo III α subunit + DNA<br />
+
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[[3f2b]], [[3f2c]], [[3f2d]], [[4iqj]] – GkDpo III α subunit + DNA + nucleotide <br />
+
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[[1zd7]], [[1zde]], [[3nzm]] - SyDpo III α subunit – Synechocystis<br />
+
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[[4gig]] - SyDpo III α subunit (mutant) <br />
+
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[[2keq]], [[4kl5]], [[4kl6]] - Dpo III α subunit – ''Nostoc punctiforme''<br />
+
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[[1ok7]] - EcDpo III + EcDpo IV C-terminal<br />
+
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[[1mmi]], [[2pol]], [[4k3s]] - EcDpo III subunit β<br />
+
-
[[2xur]], [[3f1v]], [[3pwe]] - EcDpo III subunit β (mutant)<br />
+
-
[[3d1e]] - EcDpo III subunit β + EcDpo II C-terminal<br />
+
-
[[1unn]] - EcDpo III subunit β + EcDpo IV little finger<br />
+
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[[3d1g]], [[3qsb]], [[4k3k]], [[4k3l]], [[4mjp]], [[4mjq]], [[4mjr]], [[4n94]], [[4n95]], [[4n96]], [[4n97]], [[4n98]], [[4n99]], [[4n9a]] - EcDpo III subunit β + inhibitor<br />
+
-
[[3bep]] - EcDpo III subunit β + DNA<br />
+
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[[3d1f]], [[4k3m]], [[4k3o]], [[4k3p]], [[4k3q]], [[4k3r]], [[4k74]] - EcDpo III β subunit + polypeptide<br />
+
-
[[2avt]] - Dpo III β subunit – ''Streptococcus pyogenes''<br />
+
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[[2awa]] - Dpo III β subunit – ''Streptococcus pneumoniae''<br />
+
-
[[2p1j]] – TmDpo III exonuclease domain – ''Thermotoga maritima''<br />
+
-
[[1vpk]] - TmDpo III β subunit<br />
+
-
[[3p16]], [[3rb9]] - Dpo III β subunit – ''Mycobacterrium tuberculosis''<br />
+
-
[[3q4j]], [[3q4k]], [[3q4l]], [[3d1f]] - EcDpo III β subunit + peptide<br />
+
-
[[1njf]], [[1njg]] - EcDpo III subunit γ N-terminal domains 1-2<br />
+
-
[[2gno]] - TmDpo III γ subunit<br />
+
-
[[1jqj]], [[1jql]] - EcDpo III subunit β, δ(mutant)<br />
+
-
[[1a5t]] - EcDpo III subunit δ’<br />
+
-
[[1xxh]], [[1jr3]] - EcDpo III subunit γ, δ, δ' <br />
+
-
[[1xxi]] - EcDpo III subunit γ, δ, δ' + nucleotide<br />
+
-
[[2gui]] – EcDpo III subunit ε N-terminal<br />
+
-
[[4gx8]], [[4gx9]] - EcDpo III subunit α/ε<βρ />
+
-
[[1j53]], [[1j54]], [[2gui]] - EcDpo III subunit ε N-terminal exonuclease domain<br />
+
-
[[2ido]] - EcDpo III subunit ε + HOT protein<br />
+
-
[[3glh]] - EcDpo III subunit δ, δ', τ <br />
+
-
[[3glf]] - EcDpo III subunit δ, δ', τ + DNA<br />
+
-
[[3gli]] - EcDpo III subunit δ, δ', τ, ξ + DNA<br />
+
-
[[3glg]] - EcDpo III subunit δ, δ', τ mutant DNA<br />
+
-
[[2xy8]] - EcDpo III subunit ε,θ<br />
+
-
[[2axd]], [[2ae9]], [[1du2]] - EcDpo III subunit θ - NMR<br />
+
-
[[2aya]] - EcDpo III subunit τ<br />
+
-
[[1em8]] - EcDpo III subunit φ, χ<br />
+
-
[[3sxu]] - EcDpo III subunit ϕ,χ + peptide<br />
+
-
[[1bgx]] – TaDpo + TP7 MAB<br />
+
-
===Family X – eukaryotic Dpo (β,λ,σ,μ) involved in base excision repair, non-homologous end-joining and V(D)J recombination.===
+
**[[2hnh]], [[2hqa]] - EcDpo III subunit α catalytic fragment<br />
 +
**[[4jom]] - EcDpo III α subunit (mutant)<br />
 +
**[[2hpi]], [[2hpm]] - TaDpo III α subunit<br />
 +
**[[3e0d]] - TaDpo III α subunit + DNA<br />
 +
**[[3f2b]], [[3f2c]], [[3f2d]], [[4iqj]] – GkDpo III α subunit + DNA + nucleotide <br />
 +
**[[1zd7]], [[1zde]], [[3nzm]] - SyDpo III α subunit – Synechocystis<br />
 +
**[[4gig]] - SyDpo III α subunit (mutant) <br />
 +
**[[2keq]], [[4kl5]], [[4kl6]] - Dpo III α subunit – ''Nostoc punctiforme''<br />
 +
**[[1ok7]] - EcDpo III + EcDpo IV C-terminal<br />
 +
**[[1mmi]], [[2pol]], [[4k3s]] - EcDpo III subunit β<br />
 +
**[[2xur]], [[3f1v]], [[3pwe]] - EcDpo III subunit β (mutant)<br />
 +
**[[3d1e]] - EcDpo III subunit β + EcDpo II C-terminal<br />
 +
**[[1unn]] - EcDpo III subunit β + EcDpo IV little finger<br />
 +
**[[3d1g]], [[3qsb]], [[4k3k]], [[4k3l]], [[4mjp]], [[4mjq]], [[4mjr]], [[4n94]], [[4n95]], [[4n96]], [[4n97]], [[4n98]], [[4n99]], [[4n9a]] - EcDpo III subunit β + inhibitor<br />
 +
**[[3bep]] - EcDpo III subunit β + DNA<br />
 +
**[[3d1f]], [[4k3m]], [[4k3o]], [[4k3p]], [[4k3q]], [[4k3r]], [[4k74]] - EcDpo III β subunit + polypeptide<br />
 +
**[[2avt]] - Dpo III β subunit – ''Streptococcus pyogenes''<br />
 +
**[[2awa]] - Dpo III β subunit – ''Streptococcus pneumoniae''<br />
 +
**[[2p1j]] – TmDpo III exonuclease domain – ''Thermotoga maritima''<br />
 +
**[[1vpk]] - TmDpo III β subunit<br />
 +
**[[3p16]], [[3rb9]] - Dpo III β subunit – ''Mycobacterrium tuberculosis''<br />
 +
**[[3q4j]], [[3q4k]], [[3q4l]], [[3d1f]] - EcDpo III β subunit + peptide<br />
 +
**[[1njf]], [[1njg]] - EcDpo III subunit γ N-terminal domains 1-2<br />
 +
**[[2gno]] - TmDpo III γ subunit<br />
 +
**[[1jqj]], [[1jql]] - EcDpo III subunit β, δ(mutant)<br />
 +
**[[1a5t]] - EcDpo III subunit δ’<br />
 +
**[[1xxh]], [[1jr3]] - EcDpo III subunit γ, δ, δ' <br />
 +
**[[1xxi]] - EcDpo III subunit γ, δ, δ' + nucleotide<br />
 +
**[[2gui]] – EcDpo III subunit ε N-terminal<br />
 +
**[[4gx8]], [[4gx9]] - EcDpo III subunit α/ε<βρ />
 +
**[[1j53]], [[1j54]], [[2gui]] - EcDpo III subunit ε N-terminal exonuclease domain<br />
 +
**[[2ido]] - EcDpo III subunit ε + HOT protein<br />
 +
**[[3glh]] - EcDpo III subunit δ, δ', τ <br />
 +
**[[3glf]] - EcDpo III subunit δ, δ', τ + DNA<br />
 +
**[[3gli]] - EcDpo III subunit δ, δ', τ, ξ + DNA<br />
 +
**[[3glg]] - EcDpo III subunit δ, δ', τ mutant DNA<br />
 +
**[[2xy8]] - EcDpo III subunit ε,θ<br />
 +
**[[2axd]], [[2ae9]], [[1du2]] - EcDpo III subunit θ - NMR<br />
 +
**[[2aya]] - EcDpo III subunit τ<br />
 +
**[[1em8]] - EcDpo III subunit φ, χ<br />
 +
**[[3sxu]] - EcDpo III subunit ϕ,χ + peptide<br />
 +
**[[1bgx]] – TaDpo + TP7 MAB<br />
-
[[3q8p]], [[3q8q]], [[3lk9]], [[3mby]], [[3isb]], [[3isc]], [[1zjm]], [[1tv9]], [[1tva]], [[1bpx]], [[1bpz]], [[1zqa]], [[1zqb]], [[1zqc]], [[1zqd]], [[1zqf]], [[1zqg]], [[1zqh]], [[1zqi]], [[1zaj]], [[1zqk]], [[1zql]], [[1zqm]], [[1zqn]], [[1zqo]], [[1zqp]], [[1zqq]], [[1zqr]], [[1zqs]], [[1zqt]], [[1zqu]], [[1zqv]], [[1zqw]], [[1zqx]], [[1zqy]], [[1zqz]], [[7ice]], [[7icf]], [[7ici]], [[7icj]], [[7icl]], [[7icm]], [[7icp]], [[7icr]], [[7ict]], [[7icu]], [[7icv]], [[8icb]], [[8icc]], [[9icj]], [[9ick]], [[9icl]], [[9icm]], [[9icp]], [[9icw]], [[9icx]], [[9icy]], [[7icg]], [[7ich]], [[7ick]], [[7icn]], [[7ico]], [[7icq]], [[7ics]], [[1zqe]], [[4gxi]], [[4gxj]], [[4gxk]], [[4kld]], [[4kle]], [[4klf]], [[4klg]], [[4klh]], [[4kli]], [[4klj]], [[4kll]], [[4klm]], [[4klo]], [[4klp]], [[4klq]], [[4kls]], [[4klt]], [[4klu]], [[1zqj]], [[4lvs]], [[4m2y]], [[4m47]], [[4nlk]], [[4nln]], [[4nlz]], [[4nm1]], [[4nm2]], [[3gdx]], [[3rh4]], [[3rh5]], [[3rh6]] - hDpo β + DNA<br />
+
*Family X – eukaryotic Dpo (β,λ,σ,μ) involved in base excision repair, non-homologous end-joining and V(D)J recombination
-
[[3jpn]], [[3jpo]], [[3jpp]], [[3jpq]], [[3jpr]], [[3jpt]], [[3jps]], [[3isd]], [[3c2k]], [[3c2l]], [[3c2m]], [[2pxi]], [[2iso]], [[2isp]], [[2i9g]], [[2fmp]], [[2fmq]], [[2fms]], [[1zjn]], [[1mq2]], [[1mq3]], [[1bpy]], [[8ica]], [[8ice]], [[8icf]], [[8icg]], [[8ich]], [[8ici]], [[8icj]], [[8ick]], [[8icl]], [[8icm]], [[8icn]], [[8ico]], [[8icp]], [[8icq]], [[8icr]], [[8ics]], [[8ict]], [[8icu]], [[8icv]], [[8icw]], [[8icx]], [[8icz]], [[9ice]], [[9icg]], [[9ich]], [[9ici]], [[9icq]], [[9ics]], [[9ict]], [[9icu]], [[9icv]], [[9icr]], [[9icn]], [[9ico]], [[8icy]], [[9ica]], [[9icb]], [[9icc]], [[9icf]], [[4do9]], [[4doa]], [[4dob]], [[4doc]], [[3rje]], [[3rjf]], [[3rjg]], [[3rjh]], [[3rji]], [[3rjj]], [[3rjk]], [[3tfr]], [[3tfs]] - hDpo β + DNA + nucleotide<br />
+
-
[[2p66]], [[4f5n]] - hDpo β + DNA + nucleotide analog<br />
+
-
[[4f5o]], [[4f5p]], [[4f5q]], [[4f5r]] - hDpo β (mutant) + DNA + nucleotide analog<br />
+
-
[[3ogu]], [[4jwm]], [[4jwn]], [[4m9g]], [[4m9h]], [[4m9j]], [[4m9l]], [[4m9n]] - hDpo β (mutant) + DNA<br />
+
-
[[2v6z]] - hDpo β N-terminal (mutant) - NMR<br />
+
-
[[3k75]], [[3lqc]] - hDpo β + DNA repair protein XRCC1<br />
+
-
[[2jw5]] - hDpo λ BRCT domain<br />
+
-
[[1xsl]] - hDpo λ catalytic domain<br />
+
-
[[1nzp]] - hDpo λ lyase domain - NMR<br />
+
-
[[3pmn]], [[3pnc]], [[3mda]], [[2gws]], [[2bcq]], [[2bcr]], [[2bcs]], [[2bcu]], [[2bcv]], [[1xsp]], [[1rzt]] - hDpo λ + DNA<br />
+
-
[[3mgh]], [[3c5f]], [[3c5g]], [[2pfn]] - hDpo λ (mutant) + DNA<br />
+
-
[[3pml]], [[3mdc]], [[1xsn]] - hDpo λ + DNA + nucleotide<br />
+
-
[[4k4g]], [[3k4h]], [[3k4i]] - hDpo λ + DNA + nucleotide analog<br />
+
-
[[3mgi]], [[3hw8]], [[3hwt]], [[3hx0]], [[2pfo]], [[2pfp]], [[2pfq]] - hDpo λ (mutant) + DNA + nucleotide<br />
+
-
[[3upq]], [[3uq0]], [[3uq2]] - hDpo δ (mutant) + DNA<br />
+
-
[[4fo6]] - hDpo δ (mutant) + DNA + nucleotide analog<br />
+
-
[[2htf]], [[2dun]] - hDpo μ BRCT domain – NMR<br />
+
-
[[2ihm]] - mDpo μ catalytic domain + DNA – mouse<br />
+
-
[[1rpl]], [[2bpc]], [[1bpe]], [[1bpb]], [[1bpd]], [[3uxn]] - rDpo β – rat<br />
+
-
[[2van]], [[1jn3]], [[3uxo]], [[3v7l]] - rDpo β (mutant)<br />
+
-
[[1dk2]], [[1dk3]], [[1bno]], [[1bnp]] - rDpo β N-terminal – NMR<br />
+
-
[[1nom]] - rDpo β C-terminal<br />
+
-
[[1huo]], [[1huz]], [[3v7j]] - rDpo β + DNA<br />
+
-
[[3uxp]], [[3v72]], [[3v7k]] - rDpo β (mutant) + DNA<br />
+
-
[[1bpe]] - rDpo β + nucleotide<br />
+
-
[[2bpf]], [[2bpg]] - rDpo β + DNA + nucleotide<br />
+
-
[[2w9m]] – Dpo X – ''Deinococcus radiodurans''<br />
+
-
[[3au2]] – TtDpo β + GTP – ''Thermus thermophilus''<br />
+
-
[[3b0x]], [[3b0y]] – TtDpo β (mutant) + GTP<br />
+
-
[[3au6]], [[3auo]] – TtDpo β + GTP + DNA<br />
+
-
''Terminal deoxynucleotidyl transferase''
+
**[[3q8p]], [[3q8q]], [[3lk9]], [[3mby]], [[3isb]], [[3isc]], [[1zjm]], [[1tv9]], [[1tva]], [[1bpx]], [[1bpz]], [[1zqa]], [[1zqb]], [[1zqc]], [[1zqd]], [[1zqf]], [[1zqg]], [[1zqh]], [[1zqi]], [[1zaj]], [[1zqk]], [[1zql]], [[1zqm]], [[1zqn]], [[1zqo]], [[1zqp]], [[1zqq]], [[1zqr]], [[1zqs]], [[1zqt]], [[1zqu]], [[1zqv]], [[1zqw]], [[1zqx]], [[1zqy]], [[1zqz]], [[7ice]], [[7icf]], [[7ici]], [[7icj]], [[7icl]], [[7icm]], [[7icp]], [[7icr]], [[7ict]], [[7icu]], [[7icv]], [[8icb]], [[8icc]], [[9icj]], [[9ick]], [[9icl]], [[9icm]], [[9icp]], [[9icw]], [[9icx]], [[9icy]], [[7icg]], [[7ich]], [[7ick]], [[7icn]], [[7ico]], [[7icq]], [[7ics]], [[1zqe]], [[4gxi]], [[4gxj]], [[4gxk]], [[4kld]], [[4kle]], [[4klf]], [[4klg]], [[4klh]], [[4kli]], [[4klj]], [[4kll]], [[4klm]], [[4klo]], [[4klp]], [[4klq]], [[4kls]], [[4klt]], [[4klu]], [[1zqj]], [[4lvs]], [[4m2y]], [[4m47]], [[4nlk]], [[4nln]], [[4nlz]], [[4nm1]], [[4nm2]], [[3gdx]], [[3rh4]], [[3rh5]], [[3rh6]] - hDpo β + DNA<br />
 +
**[[3jpn]], [[3jpo]], [[3jpp]], [[3jpq]], [[3jpr]], [[3jpt]], [[3jps]], [[3isd]], [[3c2k]], [[3c2l]], [[3c2m]], [[2pxi]], [[2iso]], [[2isp]], [[2i9g]], [[2fmp]], [[2fmq]], [[2fms]], [[1zjn]], [[1mq2]], [[1mq3]], [[1bpy]], [[8ica]], [[8ice]], [[8icf]], [[8icg]], [[8ich]], [[8ici]], [[8icj]], [[8ick]], [[8icl]], [[8icm]], [[8icn]], [[8ico]], [[8icp]], [[8icq]], [[8icr]], [[8ics]], [[8ict]], [[8icu]], [[8icv]], [[8icw]], [[8icx]], [[8icz]], [[9ice]], [[9icg]], [[9ich]], [[9ici]], [[9icq]], [[9ics]], [[9ict]], [[9icu]], [[9icv]], [[9icr]], [[9icn]], [[9ico]], [[8icy]], [[9ica]], [[9icb]], [[9icc]], [[9icf]], [[4do9]], [[4doa]], [[4dob]], [[4doc]], [[3rje]], [[3rjf]], [[3rjg]], [[3rjh]], [[3rji]], [[3rjj]], [[3rjk]], [[3tfr]], [[3tfs]] - hDpo β + DNA + nucleotide<br />
 +
**[[2p66]], [[4f5n]] - hDpo β + DNA + nucleotide analog<br />
 +
**[[4f5o]], [[4f5p]], [[4f5q]], [[4f5r]] - hDpo β (mutant) + DNA + nucleotide analog<br />
 +
**[[3ogu]], [[4jwm]], [[4jwn]], [[4m9g]], [[4m9h]], [[4m9j]], [[4m9l]], [[4m9n]] - hDpo β (mutant) + DNA<br />
 +
**[[2v6z]] - hDpo β N-terminal (mutant) - NMR<br />
 +
**[[3k75]], [[3lqc]] - hDpo β + DNA repair protein XRCC1<br />
 +
**[[2jw5]] - hDpo λ BRCT domain<br />
 +
**[[1xsl]] - hDpo λ catalytic domain<br />
 +
**[[1nzp]] - hDpo λ lyase domain - NMR<br />
 +
**[[3pmn]], [[3pnc]], [[3mda]], [[2gws]], [[2bcq]], [[2bcr]], [[2bcs]], [[2bcu]], [[2bcv]], [[1xsp]], [[1rzt]] - hDpo λ + DNA<br />
 +
**[[3mgh]], [[3c5f]], [[3c5g]], [[2pfn]] - hDpo λ (mutant) + DNA<br />
 +
**[[3pml]], [[3mdc]], [[1xsn]] - hDpo λ + DNA + nucleotide<br />
 +
**[[4k4g]], [[3k4h]], [[3k4i]] - hDpo λ + DNA + nucleotide analog<br />
 +
**[[3mgi]], [[3hw8]], [[3hwt]], [[3hx0]], [[2pfo]], [[2pfp]], [[2pfq]] - hDpo λ (mutant) + DNA + nucleotide<br />
 +
**[[3upq]], [[3uq0]], [[3uq2]] - hDpo δ (mutant) + DNA<br />
 +
**[[4fo6]] - hDpo δ (mutant) + DNA + nucleotide analog<br />
 +
**[[2htf]], [[2dun]] - hDpo μ BRCT domain – NMR<br />
 +
**[[2ihm]] - mDpo μ catalytic domain + DNA – mouse<br />
 +
**[[1rpl]], [[2bpc]], [[1bpe]], [[1bpb]], [[1bpd]], [[3uxn]] - rDpo β – rat<br />
 +
**[[2van]], [[1jn3]], [[3uxo]], [[3v7l]] - rDpo β (mutant)<br />
 +
**[[1dk2]], [[1dk3]], [[1bno]], [[1bnp]] - rDpo β N-terminal – NMR<br />
 +
**[[1nom]] - rDpo β C-terminal<br />
 +
**[[1huo]], [[1huz]], [[3v7j]] - rDpo β + DNA<br />
 +
**[[3uxp]], [[3v72]], [[3v7k]] - rDpo β (mutant) + DNA<br />
 +
**[[1bpe]] - rDpo β + nucleotide<br />
 +
**[[2bpf]], [[2bpg]] - rDpo β + DNA + nucleotide<br />
 +
**[[2w9m]] – Dpo X – ''Deinococcus radiodurans''<br />
 +
**[[3au2]] – TtDpo β + GTP – ''Thermus thermophilus''<br />
 +
**[[3b0x]], [[3b0y]] – TtDpo β (mutant) + GTP<br />
 +
**[[3au6]], [[3auo]] – TtDpo β + GTP + DNA<br />
-
[[2coe]] – TdT BRCT domain – NMR<br />
+
*''Terminal deoxynucleotidyl transferase''
-
[[1jms]] – mTdT catalytic domain + Mg <br / >
+
-
''Terminal deoxynucleotidyl transferase binary complex''
+
**[[2coe]] – TdT BRCT domain – NMR<br />
 +
**[[1jms]] – mTdT catalytic domain + Mg <br / >
-
[[4iqt]], [[4iqu]], [[4iqv]], [[4iqw]] – mTdT catalytic domain + inhibitor <br / >
+
*''Terminal deoxynucleotidyl transferase binary complex''
-
[[4i2i]] – mTdT catalytic domain + Mg + Zn + adenosine-pentaphosphate<br / >
+
-
[[4i2j]] – mTdT catalytic domain + CTP + Zn<br / >
+
-
[[1kej]] – mTdT catalytic domain + ATP derivative + Co <br / >
+
-
[[4i2d]] – mTdT catalytic domain + ATP derivative + Mg <br / >
+
-
[[4i29]] – mTdT catalytic domain + AMP derivative + Mn <br / >
+
-
[[4i2b]] – mTdT catalytic domain + AMPCPP + Mg <br / >
+
-
[[4i2c]] – mTdT catalytic domain + AMPCPP + Mn <br / >
+
-
[[4i2a]] – mTdT catalytic domain + UMP derivative + Mg <br / >
+
-
''Terminal deoxynucleotidyl transferase ternary complex with DNA''
+
**[[4iqt]], [[4iqu]], [[4iqv]], [[4iqw]] – mTdT catalytic domain + inhibitor <br / >
 +
**[[4i2i]] – mTdT catalytic domain + Mg + Zn + adenosine-pentaphosphate<br / >
 +
**[[4i2j]] – mTdT catalytic domain + CTP + Zn<br / >
 +
**[[1kej]] – mTdT catalytic domain + ATP derivative + Co <br / >
 +
**[[4i2d]] – mTdT catalytic domain + ATP derivative + Mg <br / >
 +
**[[4i29]] – mTdT catalytic domain + AMP derivative + Mn <br / >
 +
**[[4i2b]] – mTdT catalytic domain + AMPCPP + Mg <br / >
 +
**[[4i2c]] – mTdT catalytic domain + AMPCPP + Mn <br / >
 +
**[[4i2a]] – mTdT catalytic domain + UMP derivative + Mg <br / >
-
[[4i2e]] – mTdT catalytic domain + AMPCPP + Co + DNA <br / >
+
*''Terminal deoxynucleotidyl transferase ternary complex with DNA''
-
[[4i2h]] – mTdT catalytic domain + AMPCPP + Zn + Mg + DNA <br / >
+
-
[[4i27]] – mTdT catalytic domain + TTP derivative + TMP + Mg + DNA <br / >
+
-
[[1kdh]] – mTdT catalytic domain + UMP derivative + Mg + DNA <br / >
+
-
[[4i28]], [[4i2f]] – mTdT catalytic domain + Mg + Zn + DNA<br / >
+
-
[[4i2g]] – mTdT catalytic domain + Mg + Co + DNA<br / >
+
-
===Family Y – translesion Dpo (includes eukaryotic η,ι,κ)===
+
**[[4i2e]] – mTdT catalytic domain + AMPCPP + Co + DNA <br / >
 +
**[[4i2h]] – mTdT catalytic domain + AMPCPP + Zn + Mg + DNA <br / >
 +
**[[4i27]] – mTdT catalytic domain + TTP derivative + TMP + Mg + DNA <br / >
 +
**[[1kdh]] – mTdT catalytic domain + UMP derivative + Mg + DNA <br / >
 +
**[[4i28]], [[4i2f]] – mTdT catalytic domain + Mg + Zn + DNA<br / >
 +
**[[4i2g]] – mTdT catalytic domain + Mg + Co + DNA<br / >
-
[[2i5o]] - hDpo η ubiquitin-binding zinc finger - NMR<br />
+
*Family Y – translesion Dpo (includes eukaryotic η,ι,κ)
-
[[3si8]] - hDpo η + DNA<br />
+
-
[[3abd]], [[3abe]] - hDpo ξ catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7<br />
+
-
[[3gqc]] – hRev1 + DNA + nucleotide<br />
+
-
[[2ebw]] – hRev1 BRCT domain – NMR<br />
+
-
[[3bjy]], [[2aq4]] – yRev1 catalytic domain + DNA + nucleotide<br />
+
-
[[3q8r]], [[3q8s]], [[3h4b]], [[3h4d]], [[3gv5]], [[3gv7]], [[3gv8]], [[3epg]], [[3epi]], [[2fll]], [[2fln]], [[2flp]], [[2dpi]], [[2dpj]], [[2alz]], [[1zet]], [[1t3n]], [[4ebc]], [[4ebd]], [[4ebe]], [[4fs1]], [[4fs2]], [[4eyh]], [[4eyi]] - hDpo τ + DNA + nucleotide<br />
+
-
[[3ngd]], [[3osn]], [[3h40]] - hDpo τ catalytic fragment + DNA<br />
+
-
[[2ktf]] - hDpo τ + ubiquitin<br />
+
-
[[2l0f]], [[2l0g]] - hDpo τ + ubiquitin – NMR<br />
+
-
[[2khu]] - hDpo ι ubiquitin binding motif – NMR<br />
+
-
[[2khw]] - hDpo ι ubiquitin binding motif + ubiquitin – NMR<br />
+
-
[[3g6v]], [[3g6x]], [[3g6y]] - hDpo ι + DNA<br />
+
-
[[1t94]] - hDpo κ<br />
+
-
[[3in5]] - hDpo κ + DNA<br />
+
-
[[2w7o]], [[2w7p]], [[2oh2]], [[3pzp]] - hDpo κ + DNA + nucleotide<br />
+
-
[[4fjo]] - hDpo κ + DNA repair protein REV1 + MAD2B<br />
+
-
[[4gk0]], [[4gk5]] - hDpo η + DNA repair protein REV1 + MAD2B<br />
+
-
[[2lsj]], [[2isi]] - hDpo η + DNA repair protein REV1<br />
+
-
[[4ecq]], [[4ecr]], [[4ecs]], [[4ect]], [[4ecu]], [[4ecv]], [[4ecw]], [[4ecx]], [[4ecy]], [[4ecz]], [[4ed0]], [[4ed1]], [[4ed2]], [[4ed3]], [[4ed6]], [[4ed7]], [[4ed8]] - hDpo η + DNA + nucleotide<br />
+
-
[[2kwu]], [[2kwv]] - mDpo τ C-terminal + ubiquitin - NMR<br />
+
-
[[3ai4]] - mDpo τ/yEGFP<br />
+
-
[[1jih]] – yDpo η catalytic domain<br />
+
-
[[2lsk]] - mDpo κ + DNA repair protein REV1<br />
+
-
[[2rdi]] - SsDpo IV - ''Sulfolobus solfataricus''<br />
+
-
[[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]], - SsDpo IV (mutant) + DNA + nucleotide<br />
+
-
[[4juz]], [[4jv0]], [[4jv1]], [[4jv2]] - SsDpo IV + DNA + nucleotide<br />
+
-
[[2xc9]], [[3m9m]], [[3m9n]], [[3m9o]], [[2v4q]], [[2v4r]], [[2ago]], [[1ryr]], [[1rys]], [[2w9a]], [[2w9b]], [[2w9c]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3qz7]], [[3qz8]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]], [[4hyk]], [[4fbt]], [[4fbu]], [[4g3i]] - SsDpo IV + DNA<br />
+
-
[[2xca]], [[2xcp]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]], [[3t5h]], [[3t5j]], [[3t5k]], [[3t5l]], [[3v6h]], [[3v6j]], [[3v6k]], [[4gc6]], [[4gc7]] - SsDpo IV + DNA + nucleotide<br />
+
-
[[3fds]] – SsDpo IV + PCNA B + PCNA C<br />
+
-
[[3bq2]], [[3bq0]] – SaDpo IV + DNA – ''Sulfolobus acidocaldarius''<br />
+
-
[[3bq1]], [[4f4w]], [[4f4x]], [[4f4y]], [[4f4z]], [[4f50]] - SaDpo IV + DNA + nucleotide<br />
+
-
[[4nlg]] - SaDpo IV (mutant) + DNA<br />
+
-
[[4dez]] – Dpo IV – ''Mycobacterium smegmatis''
+
-
===Prokaryotic Pol I – DNA repair===
+
**[[2i5o]] - hDpo η ubiquitin-binding zinc finger - NMR<br />
 +
**[[3si8]] - hDpo η + DNA<br />
 +
**[[3abd]], [[3abe]] - hDpo ξ catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7<br />
 +
**[[3gqc]] – hRev1 + DNA + nucleotide<br />
 +
**[[2ebw]] – hRev1 BRCT domain – NMR<br />
 +
**[[3bjy]], [[2aq4]] – yRev1 catalytic domain + DNA + nucleotide<br />
 +
**[[3q8r]], [[3q8s]], [[3h4b]], [[3h4d]], [[3gv5]], [[3gv7]], [[3gv8]], [[3epg]], [[3epi]], [[2fll]], [[2fln]], [[2flp]], [[2dpi]], [[2dpj]], [[2alz]], [[1zet]], [[1t3n]], [[4ebc]], [[4ebd]], [[4ebe]], [[4fs1]], [[4fs2]], [[4eyh]], [[4eyi]] - hDpo τ + DNA + nucleotide<br />
 +
**[[3ngd]], [[3osn]], [[3h40]] - hDpo τ catalytic fragment + DNA<br />
 +
**[[2ktf]] - hDpo τ + ubiquitin<br />
 +
**[[2l0f]], [[2l0g]] - hDpo τ + ubiquitin – NMR<br />
 +
**[[2khu]] - hDpo ι ubiquitin binding motif – NMR<br />
 +
**[[2khw]] - hDpo ι ubiquitin binding motif + ubiquitin – NMR<br />
 +
**[[3g6v]], [[3g6x]], [[3g6y]] - hDpo ι + DNA<br />
 +
**[[1t94]] - hDpo κ<br />
 +
**[[3in5]] - hDpo κ + DNA<br />
 +
**[[2w7o]], [[2w7p]], [[2oh2]], [[3pzp]] - hDpo κ + DNA + nucleotide<br />
 +
**[[4fjo]] - hDpo κ + DNA repair protein REV1 + MAD2B<br />
 +
**[[4gk0]], [[4gk5]] - hDpo η + DNA repair protein REV1 + MAD2B<br />
 +
**[[2lsj]], [[2isi]] - hDpo η + DNA repair protein REV1<br />
 +
**[[4ecq]], [[4ecr]], [[4ecs]], [[4ect]], [[4ecu]], [[4ecv]], [[4ecw]], [[4ecx]], [[4ecy]], [[4ecz]], [[4ed0]], [[4ed1]], [[4ed2]], [[4ed3]], [[4ed6]], [[4ed7]], [[4ed8]] - hDpo η + DNA + nucleotide<br />
 +
**[[2kwu]], [[2kwv]] - mDpo τ C-terminal + ubiquitin - NMR<br />
 +
**[[3ai4]] - mDpo τ/yEGFP<br />
 +
**[[1jih]] – yDpo η catalytic domain<br />
 +
**[[2lsk]] - mDpo κ + DNA repair protein REV1<br />
 +
**[[2rdi]] - SsDpo IV - ''Sulfolobus solfataricus''<br />
 +
**[[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]], - SsDpo IV (mutant) + DNA + nucleotide<br />
 +
**[[4juz]], [[4jv0]], [[4jv1]], [[4jv2]] - SsDpo IV + DNA + nucleotide<br />
 +
**[[2xc9]], [[3m9m]], [[3m9n]], [[3m9o]], [[2v4q]], [[2v4r]], [[2ago]], [[1ryr]], [[1rys]], [[2w9a]], [[2w9b]], [[2w9c]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3qz7]], [[3qz8]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]], [[4hyk]], [[4fbt]], [[4fbu]], [[4g3i]] - SsDpo IV + DNA<br />
 +
**[[2xca]], [[2xcp]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]], [[3t5h]], [[3t5j]], [[3t5k]], [[3t5l]], [[3v6h]], [[3v6j]], [[3v6k]], [[4gc6]], [[4gc7]] - SsDpo IV + DNA + nucleotide<br />
 +
**[[3fds]] – SsDpo IV + PCNA B + PCNA C<br />
 +
**[[3bq2]], [[3bq0]] – SaDpo IV + DNA – ''Sulfolobus acidocaldarius''<br />
 +
**[[3bq1]], [[4f4w]], [[4f4x]], [[4f4y]], [[4f4z]], [[4f50]] - SaDpo IV + DNA + nucleotide<br />
 +
**[[4nlg]] - SaDpo IV (mutant) + DNA<br />
 +
**[[4dez]] – Dpo IV – ''Mycobacterium smegmatis''
-
[[1s5j]] – SsDpo I<br />
+
*Prokaryotic Pol I – DNA repair
-
[[3eyz]] - GsDpo I (mutant) + DNA <br />
+
-
[[3ez5]] - GsDpo I (mutant) + DNA + nucleotide <br />
+
-
[[3pv8]], [[3px0]], [[3px4]], [[3px6]], [[4dqi]], [[4dqp]], [[4dqq]], [[4dqr]], [[4dqs]], [[4ds4]], [[4ds5]], [[4dse]], [[4dsf]], [[4e0d]], [[4ez6]], [[4ez9]], [[4f2r]], [[4f2s]], [[4f3o]], [[4f4k]], [[4f8r]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus''
+
-
===Prokaryotic Pol II – DNA repair===
+
**[[1s5j]] – SsDpo I<br />
 +
**[[3eyz]] - GsDpo I (mutant) + DNA <br />
 +
**[[3ez5]] - GsDpo I (mutant) + DNA + nucleotide <br />
 +
**[[3pv8]], [[3px0]], [[3px4]], [[3px6]], [[4dqi]], [[4dqp]], [[4dqq]], [[4dqr]], [[4dqs]], [[4ds4]], [[4ds5]], [[4dse]], [[4dsf]], [[4e0d]], [[4ez6]], [[4ez9]], [[4f2r]], [[4f2s]], [[4f3o]], [[4f4k]], [[4f8r]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus''
-
[[3o59]] - PhDpo II large subunit - ''Pyrococcus horikoshii''<br />
+
*Prokaryotic Pol II – DNA repair
-
[[2kxe]] - PhDpo II small subunit<br />
+
-
[[1qqc]] – DeDpo II<br />
+
-
===Prokaryotic Pol IV===
+
**[[3o59]] - PhDpo II large subunit - ''Pyrococcus horikoshii''<br />
 +
**[[2kxe]] - PhDpo II small subunit<br />
 +
**[[1qqc]] – DeDpo II<br />
-
[[4ir1]], [[4ir9]], [[4irc]], [[4ird]], [[4irk]] - EcDpo IV + DNA<br />
+
*Prokaryotic Pol IV
 +
**[[4ir1]], [[4ir9]], [[4irc]], [[4ird]], [[4irk]] - EcDpo IV + DNA<br />
 +
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:29, 24 November 2014

Template:STRUCTURE 1taq

DNA polymerase (Dpo) reads a DNA strand and catalyzes the synthesis of its complementary strand. Dpo sliding clamp is made of the complex of Dpo and Proliferating Cell Nuclear Antigen (PCNA) which encircles it. The BRCT domain in Dpo is the C-terminal domain of breast cancer susceptibility protein. The Klenow fragment is a large Dpo fragment produced upon cleavage of Dpo by subtilisin. In the E. coli, the EcDpo III subunits β, γ, δ, δ' are named clamp loader. This complex assembles the β subunit sliding clamp unto the DNA. Rev1 is a Dpo involved in replication over DNA lesions. Terminal deoxynucleotidyl transferase (TdT) is a Dpo expressed in immature lymphoid cells. TdT adds nucleotides to exons during antibody gene recombination. For more details see

3D Structures of DNA polymerase

Updated on 24-November-2014

3ndk, 3ne6, 3ngi, 3nhg, 3nae, 3lzj, 3lzi, 2ozs, 2p5g, 2dy4, 1q9x, 1q9y, 1ig9, 3qep, 3rma, 3rmb, 3rmc, 3rmd, 3rwu, 3s9h, 3scx, 3si6, 3sjj, 3snn, 3spy, 3spz, 3sq0, 3sq1, 3sq2, 3sq4, 3sun, 3suo, 3sup, 3suq, 3tab, 3tae, 3taf, 3tag, 4i9q, 4j2a, 4j2b, 4j2d, 4j2e, 4khn, 4khq, 4khs, 4khu, 4khw, 4khy, 4ki4, 4ki6, 4m3r, 4m3t, 4m3u, 4m3w, 4m3x, 4m3y, 4m3z, 4m41, 4m42, 4m45 - EpDpo (mutant) + DNA + nucleotide

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