Dual specificity phosphatase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===slingshot phosphatase (SSH)===
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*Slingshot phosphatase (SSH)
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[[2nt2]] – hSSH-2L catalytic domain - human<br />
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**[[2nt2]] – hSSH-2L catalytic domain - human<br />
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===Phosphatase of regenerating liver (RPL)===
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*Phosphatase of regenerating liver (RPL)
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[[1xm2]] – hPRL-1 (mutant)<br />
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**[[1xm2]] – hPRL-1 (mutant)<br />
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[[1zck]], [[1x24]] – rPRL-1 - rat<br />
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**[[1zck]], [[1x24]] – rPRL-1 - rat<br />
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[[1zcl]] – rPRL-1 (mutant)<br />
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**[[1zcl]] – rPRL-1 (mutant)<br />
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[[1r6h]], [[1v3a]], [[2mbc]] – hPRL-3 - NMR<br />
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**[[1r6h]], [[1v3a]], [[2mbc]] – hPRL-3 - NMR<br />
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===Cdc14===
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*Cdc14
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[[1ohc]], [[1ohd]] – hCdc14B2 core domain <br />
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**[[1ohc]], [[1ohd]] – hCdc14B2 core domain <br />
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[[1ohe]] – hCdc14B2 core domain + peptide<br />
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**[[1ohe]] – hCdc14B2 core domain + peptide<br />
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===Cdc25===
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*Cdc25
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[[1qb0]], [[1cwr]], [[1cws]], [[1cwt]], [[1ym9]], [[1ymd]], [[1ymk]], [[1yml]], [[1ys0]], [[2uzq]] – hCdc25B catalytic domain <br />
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**[[1qb0]], [[1cwr]], [[1cws]], [[1cwt]], [[1ym9]], [[1ymd]], [[1ymk]], [[1yml]], [[1ys0]], [[2uzq]] – hCdc25B catalytic domain <br />
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[[2a2k]], [[2ifd]], [[2ifv]] – hCdc25B catalytic domain (mutant)<br />
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**[[2a2k]], [[2ifd]], [[2ifv]] – hCdc25B catalytic domain (mutant)<br />
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===Phosphoinositide phosphatase PTEN===
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*Phosphoinositide phosphatase PTEN
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[[1d5r]] – hPTEN (mutant)<br />
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**[[1d5r]] – hPTEN (mutant)<br />
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===Myotubularin-related protein (MTMR)===
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*Myotubularin-related protein (MTMR)
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[[1zvr]] – hMTMR2 PH-gram and phosphatase domains (mutant)<br />
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**[[1zvr]] – hMTMR2 PH-gram and phosphatase domains (mutant)<br />
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[[1zsq]] - hMTMR2 PH-gram and phosphatase domains (mutant) + phosphatidylinositol 3-phosphate<br />
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**[[1zsq]] - hMTMR2 PH-gram and phosphatase domains (mutant) + phosphatidylinositol 3-phosphate<br />
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[[1m7r]], [[1lw3]] - hMTMR2 PH-gram and phosphatase domains (mutant) + phosphate<br />
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**[[1m7r]], [[1lw3]] - hMTMR2 PH-gram and phosphatase domains (mutant) + phosphate<br />
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[[2yf0]] – hMTMR6<br />
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**[[2yf0]] – hMTMR6<br />
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===MAPK phosphatase===
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[[MAP kinase phosphatase]]
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*MAPK phosphatase see [[MAP kinase phosphatase]]
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:37, 24 November 2014

Template:STRUCTURE 1ohe

Dual specificity phosphatase (DUSP) is a phosphatase which acts on tyrosine, serine or threonine residues. There are several DUSP enzymes in mammals sharing a common catalytic mechanism. The DUSP include:
• Slingshot phosphatase
• Phosphatase of regenerating liver
• Cdc14
• Cdc25
• PTEN
• Myotubularin
• MAPK phosphatase see MAP kinase phosphatase

3D structures of dual specificity phosphatase

Updated on 24-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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