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Dual specificity protein kinase
From Proteopedia
(Difference between revisions)
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *CLK1 | |
| - | [[1z57]] – hCLK1 kinase domain + himenialdizine – human | + | **[[1z57]] – hCLK1 kinase domain + himenialdizine – human |
| - | [[2vag]] - hCLK1 kinase domain + indole inhibitor | + | **[[2vag]] - hCLK1 kinase domain + indole inhibitor |
| - | + | *CLK2 | |
| - | [[3nr9]] – hCLK2 kinase domain | + | **[[3nr9]] – hCLK2 kinase domain |
| - | + | *CLK3 | |
| - | [[2eu9]] – hCLK3 | + | **[[2eu9]] – hCLK3 |
| - | [[2exe]] – hCLK3 kinase domain, phosphorylated | + | **[[2exe]] – hCLK3 kinase domain, phosphorylated |
| - | [[2wu6]], [[2wu7]] – hCLK3 kinase domain + inhibitor | + | **[[2wu6]], [[2wu7]] – hCLK3 kinase domain + inhibitor |
| - | [[3raw]] - hCLK3 kinase domain + leucettine | + | **[[3raw]] - hCLK3 kinase domain + leucettine |
| - | + | *TTK | |
| - | [[3cek]], [[3dbq]] – hTTK kinase domain<br /> | + | **[[3cek]], [[3dbq]] – hTTK kinase domain<br /> |
| - | [[4b94]], [[4h7x]], [[4h7y]] - hTTK TPR domain<br /> | + | **[[4b94]], [[4h7x]], [[4h7y]] - hTTK TPR domain<br /> |
| - | [[3gfw]] - hTTK kinase domain + pyrolo-pyridin ligand | + | **[[3gfw]] - hTTK kinase domain + pyrolo-pyridin ligand |
| - | [[3h9f]] - hTTK kinase domain + pyrimidino-diazepin ligand | + | **[[3h9f]] - hTTK kinase domain + pyrimidino-diazepin ligand |
| - | [[2x9e]], [[3vqu]], [[3w1f]], [[4bhz]], [[4bi0]], [[4bi1]], [[4bi2]], [[4c4e]], [[4c4f]], [[4c4g]], [[4c4h]], [[4c4i]], [[4c4j]], [[4js8]], [[4jt3]] - hTTK kinase domain + inhibitor | + | **[[2x9e]], [[3vqu]], [[3w1f]], [[4bhz]], [[4bi0]], [[4bi1]], [[4bi2]], [[4c4e]], [[4c4f]], [[4c4g]], [[4c4h]], [[4c4i]], [[4c4j]], [[4js8]], [[4jt3]] - hTTK kinase domain + inhibitor |
| - | [[2zmc]] - hTTK kinase domain | + | **[[2zmc]] - hTTK kinase domain |
| - | [[2zmd]] - hTTK kinase domain (mutant) + inhibitor | + | **[[2zmd]] - hTTK kinase domain (mutant) + inhibitor |
| - | [[3hmn]] - hTTK kinase domain + ATP | + | **[[3hmn]] - hTTK kinase domain + ATP |
| - | [[3hmo]] - hTTK kinase domain + staurosporine | + | **[[3hmo]] - hTTK kinase domain + staurosporine |
| - | + | ||
| - | + | ||
| + | **[[3hmp]] - hTTK kinase domain + quinazolin ligand | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:41, 24 November 2014
Dual specificity protein kinases are kinases which act as both tyrosine kinase and serine/threonine kinase. CLK1 phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing. The dual specificity protein kinase TTK contains tetra-trico-peptide repeat domain (TPR) which serves as interaction domain between proteins.
3D structures of dual specificity protein kinase
Updated on 24-November-2014
