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Forkhead box protein

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===FOXO1===
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*FOXO1
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[[3co6]], [[3coa]] – hFOXO1 + DNA – human
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**[[3co6]], [[3coa]] – hFOXO1 + DNA – human
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===FOXO3===
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*FOXO3
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[[2uzk]] – hFOXO3 DNA-binding domain + DNA<br />
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**[[2uzk]] – hFOXO3 DNA-binding domain + DNA<br />
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[[2k86]] - hFOXO3 DNA-binding domain – NMR<br />
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**[[2lqh]], [[2lqi]] - hFOXO3 transactivation domain + CREB-binding protein – NMR<br />
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[[2lqh]], [[2lqi]] - hFOXO3 transactivation domain + CREB-binding protein – NMR<br />
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===FOXO4===
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*FOXO4
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[[3l2c]] – hFOXO4 DNA-binding domain + DNA
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**[[3l2c]] – hFOXO4 DNA-binding domain + DNA
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===FOXP1===
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*FOXP1
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[[2kiu]] – hFOXP1 DNA-binding domain (mutant) - NMR
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**[[2kiu]] – hFOXP1 DNA-binding domain (mutant) - NMR
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===[[FOXP2]]===
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*[[FOXP2]]
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[[2a07]] – hFOXP2 + DNA<br />
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**[[2a07]] – hFOXP2 + DNA<br />
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[[2as5]] – hFOXP2 DNA-binding domain + nuclear factor of activated T-cell + DNA
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**[[2as5]] – hFOXP2 DNA-binding domain + nuclear factor of activated T-cell + DNA
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===[[FOXP3]]===
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*[[FOXP3]]
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[[3qrf]] – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA<br />
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**[[3qrf]] – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA<br />
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[[4i1l]] – mFOXP3 residues 189-276 – mouse<br />
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**[[4i1l]] – mFOXP3 residues 189-276 – mouse<br />
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===FOXK2===
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*FOXK2
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[[2c6y]] – hFOXK2 DNA-binding domain + DNA
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**[[2c6y]] – hFOXK2 DNA-binding domain + DNA
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===FOXK1===
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*FOXK1
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[[2a3s]], [[2d2w]] – mFOXK1 DNA-binding domain – NMR
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**[[2a3s]], [[2d2w]] – mFOXK1 DNA-binding domain – NMR
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===FOXM1===
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*FOXM1
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[[3g73]] – hFOXM1 DNA-binding domain + DNA
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**[[3g73]] – hFOXM1 DNA-binding domain + DNA
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:45, 25 November 2014

Template:STRUCTURE 3co6 Forkhead box proteins (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see

See also Transcription and RNA Processing and Neurodevelopmental Disorders.

3D structures of FOX

Updated on 25-November-2014

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Michal Harel, Alexander Berchansky, David Canner

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