Gal3-Gal80-Gal4

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Gal3===
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*Gal3
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[[3v5r]] – yGal3 – yeast <br />
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**[[3v5r]] – yGal3 – yeast <br />
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[[3v2u]] – yGal3 + Gal80 + ATP + galactose <br />
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**[[3v2u]] – yGal3 + Gal80 + ATP + galactose <br />
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===Gal4===
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*Gal4
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[[1aw6]] – yGal4 DNA-binding domain – yeast – NMR<br />
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**[[1aw6]] – yGal4 DNA-binding domain – yeast – NMR<br />
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[[1hbw]] - yGal4 dimerization domain – NMR<br />
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**[[1hbw]] - yGal4 dimerization domain – NMR<br />
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[[3coq]] - yGal4 DNA-binding and dimerization domains + DNA<br />
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**[[3coq]] - yGal4 DNA-binding and dimerization domains + DNA<br />
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[[1d66]] – yGal4 + DNA
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**[[1d66]] – yGal4 + DNA
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===Gal80===
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*Gal80
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[[2nvw]] – KlGal80 – ''Kluyveromyces lactis'' <br />
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[[3e1k]] – KlGal80 + lactose regulatory protein Lac9 peptide <br />
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[[3btu]], [[3btv]] – yGal80 (mutant) <br />
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[[3bts]] – yGal80 + Gal4 peptide + NAD <br />
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**[[2nvw]] – KlGal80 – ''Kluyveromyces lactis'' <br />
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**[[3e1k]] – KlGal80 + lactose regulatory protein Lac9 peptide <br />
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**[[3btu]], [[3btv]] – yGal80 (mutant) <br />
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**[[3bts]] – yGal80 + Gal4 peptide + NAD <br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 12:59, 25 November 2014

PDB ID 1d66

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Yeast Gal4 complex with DNA and Zn+2 ions 1d66
Ligands:
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Gal3-Gal80-Gal4 proteins of yeast comprise a signal transducer that controls the galactose-inducible Gal4-mediated transcription activation of GAL regulon genes. In the absence of galactose Gal80 binds to Gal4 and prohibits it from activating transcription. In the presence of galactose, Gal3 binds to Gal80 to prohibit its inhibition of Gal4. For Gal4 details see User:Amir Mitchell/Gal4.

The Gal4 protein consists of a of identical subunits.

3D Structures of Gal3-Gal80-Gal4

Updated on 25-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Ann Taylor, Wayne Decatur, Jaime Prilusky

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