1lri

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[[Image:1lri.gif|left|200px]]<br /><applet load="1lri" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1lri.gif|left|200px]]
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caption="1lri, resolution 1.45&Aring;" />
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'''BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX'''<br />
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{{Structure
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|PDB= 1lri |SIZE=350|CAPTION= <scene name='initialview01'>1lri</scene>, resolution 1.45&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1LRI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phytophthora_cryptogea Phytophthora cryptogea] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=CLR:'>CLR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRI OCA].
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1LRI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Phytophthora_cryptogea Phytophthora cryptogea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRI OCA].
==Reference==
==Reference==
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The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12198300 12198300]
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The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12198300 12198300]
[[Category: Phytophthora cryptogea]]
[[Category: Phytophthora cryptogea]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sterol carrier protein]]
[[Category: sterol carrier protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:47:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:34:16 2008''

Revision as of 10:34, 20 March 2008

Image:1lri.gif


PDB ID 1lri

Drag the structure with the mouse to rotate
, resolution 1.45Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX


Overview

Cryptogein is a small 10 kDa elicitor produced by the phytoparasitic oomycete Phytophthora cryptogea. The protein also displays a sterol carrier activity. The native protein crystallizes in space group P4(1)22, with unit-cell parameters a = b = 46.51, c = 134.9 A (diffraction limit: 2.1 A). Its complex with cholesterol crystallizes in space group C222(1), with unit-cell parameters a = 30.96, b = 94.8, c = 65.3 A and a resolution enhanced to 1.45 A. The large inner non-specific hydrophobic cavity is able to accommodate a large variety of 3-beta-hydroxy sterols. Cryptogein probably acts as a sterol shuttle helping the pathogen to grow and complete its life cycle.

About this Structure

1LRI is a Single protein structure of sequence from Phytophthora cryptogea. Full crystallographic information is available from OCA.

Reference

The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:12198300

Page seeded by OCA on Thu Mar 20 12:34:16 2008

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