1lrm

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[[Image:1lrm.gif|left|200px]]<br /><applet load="1lrm" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1lrm.gif|left|200px]]
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caption="1lrm, resolution 2.1&Aring;" />
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'''Crystal structure of binary complex of the catalytic domain of human phenylalanine hydroxylase with dihydrobiopterin (BH2)'''<br />
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{{Structure
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|PDB= 1lrm |SIZE=350|CAPTION= <scene name='initialview01'>1lrm</scene>, resolution 2.1&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=HBI:7,8-DIHYDROBIOPTERIN'>HBI</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]
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|GENE= PAH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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}}
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'''Crystal structure of binary complex of the catalytic domain of human phenylalanine hydroxylase with dihydrobiopterin (BH2)'''
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==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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1LRM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FE:'>FE</scene> and <scene name='pdbligand=HBI:'>HBI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRM OCA].
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1LRM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRM OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylalanine 4-monooxygenase]]
[[Category: Phenylalanine 4-monooxygenase]]
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[[Category: FE]]
[[Category: FE]]
[[Category: HBI]]
[[Category: HBI]]
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[[Category: 13 alpha-helices]]
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[[Category: 13 alpha-helice]]
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[[Category: 6 beta-strands]]
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[[Category: 6 beta-strand]]
[[Category: basket-arrangement]]
[[Category: basket-arrangement]]
[[Category: ferric iron]]
[[Category: ferric iron]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:47:43 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:34:20 2008''

Revision as of 10:34, 20 March 2008


PDB ID 1lrm

Drag the structure with the mouse to rotate
, resolution 2.1Å
Ligands: and
Gene: PAH (Homo sapiens)
Activity: Phenylalanine 4-monooxygenase, with EC number 1.14.16.1
Coordinates: save as pdb, mmCIF, xml



Crystal structure of binary complex of the catalytic domain of human phenylalanine hydroxylase with dihydrobiopterin (BH2)


Disease

Known diseases associated with this structure: Hyperphenylalaninemia, mild OMIM:[261600], Phenylketonuria OMIM:[261600]

About this Structure

1LRM is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 12:34:20 2008

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