1lud
From Proteopedia
(Difference between revisions)
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| - | [[Image:1lud.gif|left|200px]]< | + | [[Image:1lud.gif|left|200px]] |
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| - | '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES''' | + | {{Structure |
| + | |PDB= 1lud |SIZE=350|CAPTION= <scene name='initialview01'>1lud</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=TRR:2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM'>TRR</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 1LUD is a [ | + | 1LUD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactobacillus_casei Lactobacillus casei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LUD OCA]. |
==Reference== | ==Reference== | ||
| - | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:[http:// | + | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12449420 12449420] |
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Lactobacillus casei]] | [[Category: Lactobacillus casei]] | ||
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[[Category: inhibitor/enzyme complex]] | [[Category: inhibitor/enzyme complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:35:17 2008'' |
Revision as of 10:35, 20 March 2008
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| Ligands: | and | ||||||
| Activity: | Dihydrofolate reductase, with EC number 1.5.1.3 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
About this Structure
1LUD is a Single protein structure of sequence from Lactobacillus casei. Full crystallographic information is available from OCA.
Reference
NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH., Polshakov VI, Smirnov EG, Birdsall B, Kelly G, Feeney J, J Biomol NMR. 2002 Sep;24(1):67-70. PMID:12449420
Page seeded by OCA on Thu Mar 20 12:35:17 2008
