Gcn4
From Proteopedia
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{{STRUCTURE_2dgc| PDB=2dgc | SIZE=400| SCENE= |right|CAPTION=Gcn4 complex with DNA [[2dgc]] }} | {{STRUCTURE_2dgc| PDB=2dgc | SIZE=400| SCENE= |right|CAPTION=Gcn4 complex with DNA [[2dgc]] }} | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| + | *Gcn4 | ||
| - | [[2zta]], [[1w5i]], [[2b1f]], [[2b22]], [[2ag3]], [[2oxj]], [[2oxk]], [[2r2v]], [[4c46]] – yGcn4 - yeast <br /> | + | **[[2zta]], [[1w5i]], [[2b1f]], [[2b22]], [[2ag3]], [[2oxj]], [[2oxk]], [[2r2v]], [[4c46]] – yGcn4 - yeast <br /> |
| - | [[2ovn]], [[2l56]] – yGcn4 - NMR<br /> | + | **[[2ovn]], [[2l56]] – yGcn4 - NMR<br /> |
| - | [[1u2u]] – yGcn4 dimer - NMR<br /> | + | **[[1u2u]] – yGcn4 dimer - NMR<br /> |
| - | [[4dmd]], [[1kd8]], [[1kd9]], [[1kdd]], [[4hu5]], [[4hu6]] – yGcn4 dimer <br /> | + | **[[4dmd]], [[1kd8]], [[1kd9]], [[1kdd]], [[4hu5]], [[4hu6]] – yGcn4 dimer <br /> |
| - | [[4dme]] – yGcn4 trimer <br /> | + | **[[4dme]] – yGcn4 trimer <br /> |
| - | [[3ck4]], [[3crp]], [[2ipz]] – yGcn4 tetramer <br /> | + | **[[3ck4]], [[3crp]], [[2ipz]] – yGcn4 tetramer <br /> |
| - | [[1gcl]], [[1swi]], [[1ce9]], [[1w5g]], [[1w5h]], [[1w5j]], [[1w5k]], [[1w5l]], [[1unt]], [[1unu]], [[1unv]], [[1unw]], [[1unx]], [[1uny]], [[1unz]], [[1uo0]], [[1uo1]], [[1uo2]], [[1uo3]], [[1uo4]], [[1uo5]], [[1u9f]], [[1u9g]], [[1u9h]], [[2bni]], [[2cce]], [[2ccf]], [[2ccn]], [[2ahp]], [[2hy6]], [[3i1g]], [[2wpy]], [[2wpz]], [[2wq0]], [[2wq1]], [[2wq2]], [[2wq3]], [[3k7z]], [[3gjp]], [[3m48]] – yGcn4 (mutant)<br /> | + | **[[1gcl]], [[1swi]], [[1ce9]], [[1w5g]], [[1w5h]], [[1w5j]], [[1w5k]], [[1w5l]], [[1unt]], [[1unu]], [[1unv]], [[1unw]], [[1unx]], [[1uny]], [[1unz]], [[1uo0]], [[1uo1]], [[1uo2]], [[1uo3]], [[1uo4]], [[1uo5]], [[1u9f]], [[1u9g]], [[1u9h]], [[2bni]], [[2cce]], [[2ccf]], [[2ccn]], [[2ahp]], [[2hy6]], [[3i1g]], [[2wpy]], [[2wpz]], [[2wq0]], [[2wq1]], [[2wq2]], [[2wq3]], [[3k7z]], [[3gjp]], [[3m48]] – yGcn4 (mutant)<br /> |
| - | [[1zii]], [[1zik]], [[1zil]] – yGcn4 dimer (mutant)<br /> | + | **[[1zii]], [[1zik]], [[1zil]] – yGcn4 dimer (mutant)<br /> |
| - | [[2o7h]], [[1gcm]], [[1zij]], [[1zim]], [[1piq]], [[1ij0]], [[1ij1]], [[1ij2]], [[1ij3]], [[1rb4]], [[1rb5]], [[1rb6]] – yGcn4 trimer (mutant)<br /> | + | **[[2o7h]], [[1gcm]], [[1zij]], [[1zim]], [[1piq]], [[1ij0]], [[1ij1]], [[1ij2]], [[1ij3]], [[1rb4]], [[1rb5]], [[1rb6]] – yGcn4 trimer (mutant)<br /> |
| - | [[2nrn]] – yGcn4 tetramer (mutant)<br /> | + | **[[2nrn]] – yGcn4 tetramer (mutant)<br /> |
| - | [[1fmh]] – yGcn4 dimer (mutant) - NMR<br /> | + | **[[1fmh]] – yGcn4 dimer (mutant) - NMR<br /> |
| - | [[1c94]] – yGcn4 retro<br /> | + | **[[1c94]] – yGcn4 retro<br /> |
| - | [[1ysa]], [[1dgc]], [[2dgc]] – yGcn4 dimer + DNA <br /> | + | **[[1ysa]], [[1dgc]], [[2dgc]] – yGcn4 dimer + DNA <br /> |
| - | [[2lpb]] – yGcn4 + mediator of RNA polymerase II<br /> | + | **[[2lpb]] – yGcn4 + mediator of RNA polymerase II<br /> |
| - | + | *Gcn4 fusion proteins | |
| - | [[1gk6]] – yGcn4/vimentin<br /> | + | **[[1gk6]] – yGcn4/vimentin<br /> |
| - | [[2wg5]] – yGcn4/proteasome-activating nucleotidase<br /> | + | **[[2wg5]] – yGcn4/proteasome-activating nucleotidase<br /> |
| - | [[2wg6]] – yGcn4 (mutant)/proteasome-activating nucleotidase<br /> | + | **[[2wg6]] – yGcn4 (mutant)/proteasome-activating nucleotidase<br /> |
| - | [[2yny]], [[2ynz]], [[2yo0]], [[2yo1]], [[2yo2]], [[2yo3]], [[3zmf]] – yGcn4/inner membrane protein<br /> | + | **[[2yny]], [[2ynz]], [[2yo0]], [[2yo1]], [[2yo2]], [[2yo3]], [[3zmf]] – yGcn4/inner membrane protein<br /> |
| - | [[3i5c]] – yGcn4/WSPR response regulator<br /> | + | **[[3i5c]] – yGcn4/WSPR response regulator<br /> |
| - | [[3p8m]] – yGcn4/dynein<br /> | + | **[[3p8m]] – yGcn4/dynein<br /> |
| - | [[4g2k]], [[1env]], [[1fav]], [[1gcl]], [[2q5u]], [[2q7c]], [[3g9r]] – yGcn4/virus envelope glycoprotein<br /> | + | **[[4g2k]], [[1env]], [[1fav]], [[1gcl]], [[2q5u]], [[2q7c]], [[3g9r]] – yGcn4/virus envelope glycoprotein<br /> |
| - | [[1kql]], [[2z5i]] – yGcn4/α-tropomyosin<br /> | + | **[[1kql]], [[2z5i]] – yGcn4/α-tropomyosin<br /> |
| - | [[2z5h]] – yGcn4/α-tropomyosin + troponin T<br /> | + | **[[2z5h]] – yGcn4/α-tropomyosin + troponin T<br /> |
| - | [[3bas]], [[3bat]] – yGcn4/myosin<br /> | + | **[[3bas]], [[3bat]] – yGcn4/myosin<br /> |
| - | [[1wvl]], [[2d3e]], [[2efr]], [[2efs]], [[2g9j]] – yGcn4/SAC7D + DNA<br /> | + | **[[1wvl]], [[2d3e]], [[2efr]], [[2efs]], [[2g9j]] – yGcn4/SAC7D + DNA<br /> |
| - | [[4m8m]] – yGcn4/plexin<br /> | + | **[[4m8m]] – yGcn4/plexin<br /> |
| - | + | *Gcn4 complex with protein | |
| + | **[[1ld4]] – yGcn4 + virus coat protein + virus spike glycoprotein<br /> | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:13, 26 November 2014
Gcn4 is a yeast transcriptional activator. It belongs to a large family of eukaryotic transcription factors including Fos, Jun and CREB. All family members have a DNA recognition motif consists of a coiled-coil dimerization element, the leucine-zipper, and an adjoining basic region, which mediates DNA binding. This basic region is largely unstructured in the absence of DNA, addition of DNA containing a Gcn4 binding site induce the transition of this region from unstructured to α-helical. See also Intrinsically Disordered Protein.
3D Structures of Gcn4
Updated on 26-November-2014
