1lx7

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[[Image:1lx7.gif|left|200px]]<br /><applet load="1lx7" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1lx7.gif|left|200px]]
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caption="1lx7, resolution 2.00&Aring;" />
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'''Structure of E. coli uridine phosphorylase at 2.0A'''<br />
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{{Structure
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|PDB= 1lx7 |SIZE=350|CAPTION= <scene name='initialview01'>1lx7</scene>, resolution 2.00&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY= [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3]
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|GENE=
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}}
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'''Structure of E. coli uridine phosphorylase at 2.0A'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1LX7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Active as [http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LX7 OCA].
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1LX7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LX7 OCA].
==Reference==
==Reference==
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Structure of Escherichia coli uridine phosphorylase at 2.0 A., Burling FT, Kniewel R, Buglino JA, Chadha T, Beckwith A, Lima CD, Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):73-6. Epub 2002 Dec, 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12499542 12499542]
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Structure of Escherichia coli uridine phosphorylase at 2.0 A., Burling FT, Kniewel R, Buglino JA, Chadha T, Beckwith A, Lima CD, Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):73-6. Epub 2002 Dec, 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12499542 12499542]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: udrpase]]
[[Category: udrpase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:49:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:36:14 2008''

Revision as of 10:36, 20 March 2008

Image:1lx7.gif


PDB ID 1lx7

Drag the structure with the mouse to rotate
, resolution 2.00Å
Activity: Uridine phosphorylase, with EC number 2.4.2.3
Coordinates: save as pdb, mmCIF, xml



Structure of E. coli uridine phosphorylase at 2.0A


Overview

The 2.0 A crystal structure has been determined for Escherichia coli uridine phosphorylase (UP), an essential enzyme in nucleotide biosynthesis that catalyzes the phosphorolytic cleavage of the C-N glycosidic bond of uridine to ribose-1-phosphate and uracil. The structure determination of two independent monomers in the asymmetric unit revealed the residue composition and atomic details of the apo configurations of each active site. The native hexameric UP enzyme was revealed by applying threefold crystallographic symmetry to the contents of the asymmetric unit. The 2.0 A model reveals a closer structural relationship to other nucleotide phosphorylase enzymes than was previously appreciated.

About this Structure

1LX7 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of Escherichia coli uridine phosphorylase at 2.0 A., Burling FT, Kniewel R, Buglino JA, Chadha T, Beckwith A, Lima CD, Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):73-6. Epub 2002 Dec, 19. PMID:12499542

Page seeded by OCA on Thu Mar 20 12:36:14 2008

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