Glutaminase
From Proteopedia
(Difference between revisions)
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| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *GLN | |
| - | [[3if5]], [[3ih8]], [[3ih9]], [[3agd]] – MlGLN – ''Micrococcus luteus''<br /> | + | **[[3if5]], [[3ih8]], [[3ih9]], [[3agd]] – MlGLN – ''Micrococcus luteus''<br /> |
| - | [[2pby]] – GLN – ''Geobacillus kaustophilus''<br /> | + | **[[2pby]] – GLN – ''Geobacillus kaustophilus''<br /> |
| - | [[2zk9]] – CpGLN – ''Chryseobacterium proteolyticum''<br /> | + | **[[2zk9]] – CpGLN – ''Chryseobacterium proteolyticum''<br /> |
| - | [[3a54]], [[3a55]], [[3a56]] – CpGLN (mutant)<br /> | + | **[[3a54]], [[3a55]], [[3a56]] – CpGLN (mutant)<br /> |
| - | [[3agf]] - BsGLN – ''Bacillus subtilis''<br /> | + | **[[3agf]] - BsGLN – ''Bacillus subtilis''<br /> |
| - | [[3ss3]], [[3ss4]] – mGLN C – mouse<br /> | + | **[[3ss3]], [[3ss4]] – mGLN C – mouse<br /> |
| - | [[4jkt]] - mGLN kidney isoform<br /> | + | **[[4jkt]] - mGLN kidney isoform<br /> |
| - | [[3voy]] – hGLN kidney isoform – human<br /> | + | **[[3voy]] – hGLN kidney isoform – human<br /> |
| - | [[4bqm]] - hGLN liver isoform<br /> | + | **[[4bqm]] - hGLN liver isoform<br /> |
| - | + | *GLN complex | |
| - | [[3brm]] – BsGLN + norleucine <br /> | + | **[[3brm]] – BsGLN + norleucine <br /> |
| - | [[3czd]], [[3unw]] – hGLN + Glu<br /> | + | **[[3czd]], [[3unw]] – hGLN + Glu<br /> |
| - | [[3vp0]] – hGLN + Gln<br /> | + | **[[3vp0]] – hGLN + Gln<br /> |
| - | [[3uo9]], [[3voz]], [[3vp2]], [[3vp3]], [[3vp4]] - hGLN + inhibitor<br /> | + | **[[3uo9]], [[3voz]], [[3vp2]], [[3vp3]], [[3vp4]] - hGLN + inhibitor<br /> |
| - | [[3iha]], [[3ihb]], [[3age]] - MlGLN + Glu<br /> | + | **[[3iha]], [[3ihb]], [[3age]] - MlGLN + Glu<br /> |
| - | [[3ss5]] – mGLN + Glu<br /> | + | **[[3ss5]] – mGLN + Glu<br /> |
| - | [[3vp1]] - hGLN + inhibitor + Glu<br /> | + | **[[3vp1]] - hGLN + inhibitor + Glu<br /> |
| - | + | *GLN-ASN | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| + | **[[1agx]] – GLN-ASN – ''Acinetobacter glutaminacificans''<br /> | ||
| + | **[[3pga]], [[4pga]] – PsGLN-ASN – ''Pseudomonas''<br /> | ||
| + | **[[1djo]], [[1djp]] - PsGLN-ASN + norvaline derivative<br /> | ||
| + | }} | ||
Revision as of 08:07, 26 November 2014
Glutaminase (GLN) catalyzes the conversion of glutamine (Gln) to glutamic acid (Glu). GLN is present at the axonal termini of neurons where GA functions as a neurotransmitter. ADP is an activator of GLN. GLN is a homodimer. In human GLN is found as 2 isozymes – GLN and GLN 2. Glutaminase-asparaginase (GLN-ASN) can amidohydrolase both glutamine and asparagine to their corresponding Glu and Asp.
3D structures of glutaminase
Updated on 26-November-2014
1u60 - YbaS
3brm - YbgJ in a complex with DON
1mki - YbgJ free
Created with the participation of Lindsey Butler.
