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4p60

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'''Unreleased structure'''
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==Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state==
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<StructureSection load='4p60' size='340' side='right' caption='[[4p60]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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The entry 4p60 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4p60]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P60 FirstGlance]. <br>
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Authors: Thangaratnarajah, C., Ruprecht, J.J., Kunji, E.R.S.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5x|4p5x]]</td></tr>
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Description: Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p60 RCSB], [http://www.ebi.ac.uk/pdbsum/4p60 PDBsum]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Epileptic encephalopathy with global cerebral demyelination. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.<ref>PMID:11566871</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Kunji, E R.S]]
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[[Category: Ruprecht, J J]]
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[[Category: Thangaratnarajah, C]]
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[[Category: Transport protein]]

Revision as of 08:11, 26 November 2014

Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state

4p60, resolution 2.40Å

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