4p60
From Proteopedia
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| - | ''' | + | ==Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state== |
| - | + | <StructureSection load='4p60' size='340' side='right' caption='[[4p60]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4p60]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P60 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5x|4p5x]]</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p60 RCSB], [http://www.ebi.ac.uk/pdbsum/4p60 PDBsum]</span></td></tr> | |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Epileptic encephalopathy with global cerebral demyelination. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.<ref>PMID:11566871</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Kunji, E R.S]] | ||
| + | [[Category: Ruprecht, J J]] | ||
| + | [[Category: Thangaratnarajah, C]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 08:11, 26 November 2014
Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state
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