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4ph9

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'''Unreleased structure'''
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==The structure of Ibuprofen bound to cyclooxygenase-2==
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<StructureSection load='4ph9' size='340' side='right' caption='[[4ph9]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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The entry 4ph9 is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ph9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PH9 FirstGlance]. <br>
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Authors: Orlando, B.J., Lucido, M.J., Malkowski, M.G.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKR:ACRYLIC+ACID'>AKR</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IBP:IBUPROFEN'>IBP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qmo|3qmo]], [[1eqg|1eqg]], [[3hs5|3hs5]], [[3nt1|3nt1]]</td></tr>
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Description:
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ph9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ph9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ph9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ph9 PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: Lucido, M J]]
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[[Category: Malkowski, M G]]
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[[Category: Orlando, B J]]
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[[Category: Cox]]
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[[Category: Cox-2]]
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[[Category: Cyclooxygenase]]
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[[Category: Ibuprofen]]
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[[Category: Membrane protein]]
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[[Category: Monotopic]]
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[[Category: Nsaid]]
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[[Category: Oxidoreductase]]
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[[Category: Prostaglandin]]

Revision as of 08:12, 26 November 2014

The structure of Ibuprofen bound to cyclooxygenase-2

4ph9, resolution 1.81Å

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