1m1c
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1m1c.jpg|left|200px]] | + | [[Image:1m1c.jpg|left|200px]] |
| - | + | ||
| - | '''Structure of the L-A virus''' | + | {{Structure |
| + | |PDB= 1m1c |SIZE=350|CAPTION= <scene name='initialview01'>1m1c</scene>, resolution 3.5Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Structure of the L-A virus''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1M1C is a [ | + | 1M1C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_virus_l-a Saccharomyces cerevisiae virus l-a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M1C OCA]. |
==Reference== | ==Reference== | ||
| - | L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism., Naitow H, Tang J, Canady M, Wickner RB, Johnson JE, Nat Struct Biol. 2002 Oct;9(10):725-8. PMID:[http:// | + | L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism., Naitow H, Tang J, Canady M, Wickner RB, Johnson JE, Nat Struct Biol. 2002 Oct;9(10):725-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12244300 12244300] |
[[Category: Saccharomyces cerevisiae virus l-a]] | [[Category: Saccharomyces cerevisiae virus l-a]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 21: | Line 30: | ||
[[Category: icosahedral virus]] | [[Category: icosahedral virus]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:37:40 2008'' |
Revision as of 10:37, 20 March 2008
| |||||||
| , resolution 3.5Å | |||||||
|---|---|---|---|---|---|---|---|
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Structure of the L-A virus
Overview
The structure of the yeast L-A virus was determined by X-ray crystallography at 3.4 A resolution. The L-A dsRNA virus is 400 A in diameter and contains a single protein shell of 60 asymmetric dimers of the coat protein, a feature common among the inner protein shells of dsRNA viruses and probably related to their unique mode of transcription and replication. The two identical subunits in each dimer are in non-equivalent environments and show substantially different conformations in specific surface regions. The L-A virus decaps cellular mRNA to efficiently translate its own uncapped mRNA. Our structure reveals a trench at the active site of the decapping reaction and suggests a role for nearby residues in the reaction.
About this Structure
1M1C is a Single protein structure of sequence from Saccharomyces cerevisiae virus l-a. Full crystallographic information is available from OCA.
Reference
L-A virus at 3.4 A resolution reveals particle architecture and mRNA decapping mechanism., Naitow H, Tang J, Canady M, Wickner RB, Johnson JE, Nat Struct Biol. 2002 Oct;9(10):725-8. PMID:12244300
Page seeded by OCA on Thu Mar 20 12:37:40 2008
