1m42

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[[Image:1m42.gif|left|200px]]<br /><applet load="1m42" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1m42.gif|left|200px]]
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caption="1m42" />
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'''Solution structure of apoCopC from Pseudomonas syringae'''<br />
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{{Structure
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|PDB= 1m42 |SIZE=350|CAPTION= <scene name='initialview01'>1m42</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE= COPC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=317 Pseudomonas syringae])
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}}
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'''Solution structure of apoCopC from Pseudomonas syringae'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1M42 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M42 OCA].
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1M42 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_syringae Pseudomonas syringae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M42 OCA].
==Reference==
==Reference==
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Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis., Arnesano F, Banci L, Bertini I, Thompsett AR, Structure. 2002 Oct;10(10):1337-47. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12377120 12377120]
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Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis., Arnesano F, Banci L, Bertini I, Thompsett AR, Structure. 2002 Oct;10(10):1337-47. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12377120 12377120]
[[Category: Pseudomonas syringae]]
[[Category: Pseudomonas syringae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Thompsett, A R.]]
[[Category: Thompsett, A R.]]
[[Category: copper trafficking]]
[[Category: copper trafficking]]
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[[Category: cupredoxins]]
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[[Category: cupredoxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:51:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:38:35 2008''

Revision as of 10:38, 20 March 2008


PDB ID 1m42

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Gene: COPC (Pseudomonas syringae)
Coordinates: save as pdb, mmCIF, xml



Solution structure of apoCopC from Pseudomonas syringae


Overview

The structure of the metal-free form of CopC, a protein involved in copper homeostasis, has been obtained. The fold is a Greek key beta barrel similar to that of functionally unrelated blue copper proteins but with important structural variations. The protein binds one equivalent of copper (II) with relatively high affinity and contains a cluster of conserved residues (His1, Glu27, Asp89, and His91) which could form a water-accessible metal binding site. The structure also reveals a loop containing the M(X)(n)M motif which is present in a number of proteins also involved in copper homeostasis. The present structure represents a link between copper-trafficking proteins and cupredoxins. Within a structural and genomic analysis, the role of CopC in copper trafficking is discussed.

About this Structure

1M42 is a Single protein structure of sequence from Pseudomonas syringae. Full crystallographic information is available from OCA.

Reference

Solution structure of CopC: a cupredoxin-like protein involved in copper homeostasis., Arnesano F, Banci L, Bertini I, Thompsett AR, Structure. 2002 Oct;10(10):1337-47. PMID:12377120

Page seeded by OCA on Thu Mar 20 12:38:35 2008

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