Glycerol kinase
From Proteopedia
(Difference between revisions)
| Line 11: | Line 11: | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *Glycerol kinase | |
| - | [[1r59]] – EncGK – ''Enterococcus casseliflavus''<br /> | + | **[[1r59]] – EncGK – ''Enterococcus casseliflavus''<br /> |
| - | [[2dpn]] - GK - ''Thermus thermophilus''<br /> | + | **[[2dpn]] - GK - ''Thermus thermophilus''<br /> |
| - | [[2d4w]] - GK - ''Cellulomonas''<br /> | + | **[[2d4w]] - GK - ''Cellulomonas''<br /> |
| - | [[2zf5]] - GK - ''Thermococcus kodakarensis''<br /> | + | **[[2zf5]] - GK - ''Thermococcus kodakarensis''<br /> |
| - | [[3gg4]] – GK – ''Yersinia pseudotuberculosis'' | + | **[[3gg4]] – GK – ''Yersinia pseudotuberculosis'' |
| - | + | *Glycerol kinase binary complex with glycerol | |
| - | [[1xup]] - EncGK + glycerol<br /> | + | **[[1xup]] - EncGK + glycerol<br /> |
| - | [[3flc]], [[3d7e]], [[3h3n]], [[3h46]] - EncGK (mutant) + glycerol<br /> | + | **[[3flc]], [[3d7e]], [[3h3n]], [[3h46]] - EncGK (mutant) + glycerol<br /> |
| - | [[3g25]] - SaGK + glycerol– ''Staphylococcus aureus''<br /> | + | **[[3g25]] - SaGK + glycerol– ''Staphylococcus aureus''<br /> |
| - | [[4e1j]] – GK + glycerol – ''Sinorhizobium meliloti''<br /> | + | **[[4e1j]] – GK + glycerol – ''Sinorhizobium meliloti''<br /> |
| - | [[1bu6]], [[3ezw]] - EcGK (mutant) + glycerol<br /> | + | **[[1bu6]], [[3ezw]] - EcGK (mutant) + glycerol<br /> |
| - | + | *Glycerol kinase ternary complex | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| + | **[[1gla]] – EcGK + IIA(Glc) + glycerol – ''Escherichia coli''<br /> | ||
| + | **[[1glb]] - EcGK + IIA(Glc) + ADP + glycerol<br /> | ||
| + | **[[1glc]], [[1gld]], [[1gle]] – EcGK + G3P + ADP<br /> | ||
| + | **[[1glf]] - EcGK + phosphate + ADP + glycerol<br /> | ||
| + | **[[1bo5]] - EcGK + FBP + glycerol<br /> | ||
| + | **[[1bot]] - EcGK + piperazine derivative + glycerol<br /> | ||
| + | **[[1bwf]], [[1glj]], [[1gll]] - EcGK (mutant) + ATP analog + glycerol<br /> | ||
| + | **[[3ge1]] - SaGK + ADP + glycerol<br /> | ||
| + | **[[3h3o]] - EncGK (mutant) + phosphate + glycerol<br /> | ||
| + | **[[3h45]] - EncGK (mutant) + phosphate + ethylene glycol | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:30, 26 November 2014
Template:STRUCTURE 1r59
Glycerol kinase (GK) phosphorylates glycerol forming glycerol 3-phosphate (G3P) using Mg-ATP as phosphate source. GK is a key enzyme in glycerol uptake and metabolism. Mutations of GK gene cause GK deficiency syndrome. PK is a multi-subunit allosteric enzyme. Its activity can be inhibited by fructose 1,6-bisphosphate (FBP) and by the glucose-specific phosphocarrier IIA(Glc). PK cofactor is a Zn atom which binds to the dimer.
3D structures of glycerol kinase
Updated on 26-November-2014
