Growth factor receptor-bound protein

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===GRB2===
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*GRB2
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[[1gri]], [[2h46]] – hGRB2 – human <br />
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**[[1gri]], [[2h46]] – hGRB2 – human <br />
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''GRB2 C terminal SH3 domain''
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*''GRB2 C terminal SH3 domain''
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[[1gfc]], [[1gfd]] – hGRB2 C terminal SH3 domain - NMR<br />
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**[[1gfc]], [[1gfd]] – hGRB2 C terminal SH3 domain - NMR<br />
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[[2vvk]], [[2vwf]], [[2w0z]] – hGRB2 C terminal SH3 domain <br />
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**[[2vvk]], [[2vwf]], [[2w0z]] – hGRB2 C terminal SH3 domain <br />
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[[1io6]] – hGRB2 C terminal SH3 domain + ligand peptide - NMR<br />
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**[[1io6]] – hGRB2 C terminal SH3 domain + ligand peptide - NMR<br />
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[[1gcq]] – hGRB2 C terminal SH3 domain + VAV proto-oncogene SH3 domain<br />
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**[[1gcq]] – hGRB2 C terminal SH3 domain + VAV proto-oncogene SH3 domain<br />
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''GRB2 N terminal SH3 domain''
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*''GRB2 N terminal SH3 domain''
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[[1gbr]], [[1gbq]], [[2gbq]], [[3gbq]], [[4gbq]] – mGRB2 N terminal SH3 domain + Sos-A peptide – mouse - NMR<br />
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**[[1gbr]], [[1gbq]], [[2gbq]], [[3gbq]], [[4gbq]] – mGRB2 N terminal SH3 domain + Sos-A peptide – mouse - NMR<br />
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[[1aze]] – mGRB2 N terminal SH3 domain + Sos-A peptide - NMR<br />
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**[[1aze]] – mGRB2 N terminal SH3 domain + Sos-A peptide - NMR<br />
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''GRB2 SH2 domain''
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*''GRB2 SH2 domain''
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[[1jyu]] – hGRB2 SH2 domain <br />
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**[[1jyu]] – hGRB2 SH2 domain <br />
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[[1ghu]] – hGRB2 SH2 domain (mutant) - NMR<br />
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**[[1ghu]] – hGRB2 SH2 domain (mutant) - NMR<br />
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[[1fhs]] – hGRB2 SH2 domain - NMR<br />
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**[[1fhs]] – hGRB2 SH2 domain - NMR<br />
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[[1x0n]] – hGRB2 SH2 domain + inhibitor - NMR<br />
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**[[1x0n]] – hGRB2 SH2 domain + inhibitor - NMR<br />
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[[2huw]] – hGRB2 SH2 domain + cyclopropane derivative<br />
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**[[2huw]] – hGRB2 SH2 domain + cyclopropane derivative<br />
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[[1cj1]] – hGRB2 SH2 domain + phosphor-Tyr derivative<br />
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**[[1cj1]] – hGRB2 SH2 domain + phosphor-Tyr derivative<br />
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[[2aoa]], [[2aob]] – hGRB2 SH2 domain + peptide mimetic<br />
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**[[2aoa]], [[2aob]] – hGRB2 SH2 domain + peptide mimetic<br />
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[[1tze]], [[1bmb]], [[1bm2]], [[1zfp]], [[1fyr]], [[1jyq]], [[1jyr]], [[2h5k]], [[3c7i]], [[3imd]], [[3imj]], [[3in7]], [[3in8]], [[3kfj]], [[3n8m]], [[3n7y]], [[3n84]], [[3mxc]], [[3mxy]], [[3ov1]], [[3ove]], [[3s8l]], [[3s8n]], [[3s8o]], [[1zfp]] – hGRB2 SH2 domain + phosphor-Tyr peptide<br />
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**[[1tze]], [[1bmb]], [[1bm2]], [[1zfp]], [[1fyr]], [[1jyq]], [[1jyr]], [[2h5k]], [[3c7i]], [[3imd]], [[3imj]], [[3in7]], [[3in8]], [[3kfj]], [[3n8m]], [[3n7y]], [[3n84]], [[3mxc]], [[3mxy]], [[3ov1]], [[3ove]], [[3s8l]], [[3s8n]], [[3s8o]], [[1zfp]] – hGRB2 SH2 domain + phosphor-Tyr peptide<br />
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[[1qg1]] – hGRB2 SH2 domain + phosphor-Tyr peptide - NMR<br />
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**[[1qg1]] – hGRB2 SH2 domain + phosphor-Tyr peptide - NMR<br />
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[[3wa4]] - hGRB2 SH2 domain + CD28 peptide <br />
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**[[3wa4]] - hGRB2 SH2 domain + CD28 peptide <br />
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===GRB4===
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*GRB4
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[[4e6r]] – hGRB4 C terminal SH3 domain <br />
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**[[4e6r]] – hGRB4 C terminal SH3 domain <br />
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===GRB7===
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*GRB7
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[[2qms]] – hGRB7 SH2 domain <br />
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**[[2qms]] – hGRB7 SH2 domain <br />
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[[1mw4]], [[2l4k]] – hGRB7 SH2 domain + phosphor-Tyr peptide - NMR<br />
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**[[1mw4]], [[2l4k]] – hGRB7 SH2 domain + phosphor-Tyr peptide - NMR<br />
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[[3pqz]] – hGRB7 SH2 domain + cyclic peptide <br />
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**[[3pqz]] – hGRB7 SH2 domain + cyclic peptide <br />
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[[1wgr]] – hGRB7 RA domain - NMR<br />
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**[[1wgr]] – hGRB7 RA domain - NMR<br />
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===GRB10===
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*GRB10
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[[1nrv]] – hGRB10 SH2 domain <br />
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**[[1nrv]] – hGRB10 SH2 domain <br />
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[[3m7f]] – hGRB10 SH2 domain + NEDD4 C2 domain<br />
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**[[3m7f]] – hGRB10 SH2 domain + NEDD4 C2 domain<br />
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[[3hk0]] – hGRB10 RA and PH domains <br />
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**[[3hk0]] – hGRB10 RA and PH domains <br />
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===GRB14===
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*GRB14
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[[2aug]] – hGRB14 SH2 domain <br />
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[[2auh]] – hGRB14 BPS domain + insulin receptor kinase domain<br />
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[[4k81]] – hGRB14 RA and PH domains + GTPase Hras<br />
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**[[2aug]] – hGRB14 SH2 domain <br />
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**[[2auh]] – hGRB14 BPS domain + insulin receptor kinase domain<br />
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**[[4k81]] – hGRB14 RA and PH domains + GTPase Hras<br />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:39, 26 November 2014

Structure of human Grb2 SH2 domain (pink) complex with phosphotyrosyl heptapeptide (gold) (PDB entry 1tze)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky

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