Hyaluronidase
From Proteopedia
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|[[Image:Hyal reaction.jpg|thumb|right|'''Hyaluronidase cleaves the β1,4-glycosidic bond of the glycosaminoglycan hyaluronan''' |400px]] | |[[Image:Hyal reaction.jpg|thumb|right|'''Hyaluronidase cleaves the β1,4-glycosidic bond of the glycosaminoglycan hyaluronan''' |400px]] | ||
|} | |} | ||
| - | + | </StructureSection> | |
==3D structures of hyaluronidase== | ==3D structures of hyaluronidase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *Hyaluronidase | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | **[[1egu]], [[2brw]] – SpHU – ''Streptococcus pneumoniae'' <br /> | |
| + | **[[1n7n]], [[1n7o]], [[1n7p]] – SpHU (mutant) <br /> | ||
| + | **[[1fcq]], [[1fcu]] – bHU – bee<br /> | ||
| + | **[[1f1s]] – SaHU – ''Streptococcus agalactiae'' <br /> | ||
| + | **[[2c3f]], [[2dp5]], [[2yw0]], [[2yx2]], [[2wb3]], [[2wh7]] - SpyHU – ''Streptococcus pyogenes''<br /> | ||
| + | **[[2cbi]], [[2w1q]], [[2w1s]] - CpHU – ''Clostridium perfringens''<br /> | ||
| + | **[[2jnk]] - CpHU residues 1498-1628]] - NMR<br /> | ||
| + | **[[2atm]] - HU – ''Vespula vulgaris''<br /> | ||
| + | **[[2pe4]] – HU-1 – human | ||
| + | |||
| + | *Hyaluronidase binary complex | ||
| + | |||
| + | **[[1c82]] – SpHU + HUA disaccharide <br /> | ||
| + | **[[1f9g]] – SpHU + ascorbate <br /> | ||
| + | **[[2brv]]– SpHU + malonate<br /> | ||
| + | **[[1fcv]] - bHU + HUA<br /> | ||
| + | **[[1i8q]] - SaHU + HUA disaccharide <br /> | ||
| + | **[[1loh]], [[1lxk]] - SpHU + glucuronic acid<br /> | ||
| + | **[[1n7q]], [[1n7r]] - SpHU (mutant) + glucuronic acid<br /> | ||
| + | **[[1lxm]] - SaHU + glucuronic acid<br /> | ||
| + | **[[1ojm]], [[1ojp]] - SpHU + condroitin disaccharide <br /> | ||
| + | **[[1ojn]], [[1ojo]] - SpHU (mutant) + condroitin disaccharide <br /> | ||
| + | **[[1w3y]] - SpHU + palmitoyl-vitamin C <br /> | ||
| + | **[[2cbj]] - CpHU + PugNac<br /> | ||
| + | **[[2j1a]] - CpHU + galactose<br /> | ||
| + | **[[2j1e]] - CpHU + LacNac<br /> | ||
| + | **[[2j7m]], [[2w1u]], [[2wdb]] - CpHU + carbohydrates<br /> | ||
| + | **[[2j62]] - CpHU + GlcNac-statin<br /> | ||
| + | **[[2brp]] – SpHU + inbhibitor<br /> | ||
| + | **[[2j88]] - bHU + FAB<br /> | ||
| + | **[[2yvv]] - SpyHU + lactose<br /> | ||
| + | **[[3eka]] - SpyHU + ascorbate <br /> | ||
| + | }} | ||
| - | [[1c82]] – SpHU + HUA disaccharide <br /> | ||
| - | [[1f9g]] – SpHU + ascorbate <br /> | ||
| - | [[2brv]]– SpHU + malonate<br /> | ||
| - | [[1fcv]] - bHU + HUA<br /> | ||
| - | [[1i8q]] - SaHU + HUA disaccharide <br /> | ||
| - | [[1loh]], [[1lxk]] - SpHU + glucuronic acid<br /> | ||
| - | [[1n7q]], [[1n7r]] - SpHU (mutant) + glucuronic acid<br /> | ||
| - | [[1lxm]] - SaHU + glucuronic acid<br /> | ||
| - | [[1ojm]], [[1ojp]] - SpHU + condroitin disaccharide <br /> | ||
| - | [[1ojn]], [[1ojo]] - SpHU (mutant) + condroitin disaccharide <br /> | ||
| - | [[1w3y]] - SpHU + palmitoyl-vitamin C <br /> | ||
| - | [[2cbj]] - CpHU + PugNac<br /> | ||
| - | [[2j1a]] - CpHU + galactose<br /> | ||
| - | [[2j1e]] - CpHU + LacNac<br /> | ||
| - | [[2j7m]], [[2w1u]], [[2wdb]] - CpHU + carbohydrates<br /> | ||
| - | [[2j62]] - CpHU + GlcNac-statin<br /> | ||
| - | [[2brp]] – SpHU + inbhibitor<br /> | ||
| - | [[2j88]] - bHU + FAB<br /> | ||
| - | [[2yvv]] - SpyHU + lactose<br /> | ||
| - | [[3eka]] - SpyHU + ascorbate <br /> | ||
| - | </StructureSection> | ||
==Reference== | ==Reference== | ||
Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis., Chao KL, Muthukumar L, Herzberg O, Biochemistry. 2007 Jun 12;46(23):6911-20. Epub 2007 May 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17503783 17503783] | Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis., Chao KL, Muthukumar L, Herzberg O, Biochemistry. 2007 Jun 12;46(23):6911-20. Epub 2007 May 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17503783 17503783] | ||
Revision as of 10:25, 27 November 2014
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3D structures of hyaluronidase
Updated on 27-November-2014
Reference
Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis., Chao KL, Muthukumar L, Herzberg O, Biochemistry. 2007 Jun 12;46(23):6911-20. Epub 2007 May 16. PMID:17503783
Created with the participation of Osnat Herzberg, Eran Hodis, Joel L. Sussman, Jaime Prilusky.
