Cas9

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	==3D structures of Cas9==		==3D structures of Cas9==
-	=== ''Streptococcus pyogenes'' Cas9===	+	* [[4un3], [[4un4]], and [[4un5]] - ''S. pyogenes'' Cas9 bound to sgRNA and target DNA
	* [[4oo8]]		* [[4oo8]]
	* [[4cmp]]		* [[4cmp]]

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Revision as of 03:46, 28 November 2014

Cas9 is the RNA-guided DNA endonuclease used by the CRISPR-associated systems to generate double-strand DNA breaks in the invading DNA during an adaptive bacterial immune response.

It has been exploited for use in genome editing systems.

Articles in Proteopedia concerning Cas9 include:

• any?

Contents 1 3D structures of Cas9 1.1 Actinomyces naeslundii Cas9 2 See Also 3 References

3D structures of Cas9

• [[4un3], 4un4, and 4un5 - S. pyogenes Cas9 bound to sgRNA and target DNA
• 4oo8
• 4cmp
• 4cmq - Mn²⁺-bound S. pyogenes Cas9

Actinomyces naeslundii Cas9

• 4oge
• 4ogc - Mn²⁺-bound A.s naeslundii Cas9

See Also

HNH endonuclease

References