Cas9
From Proteopedia
(Difference between revisions)
m |
m (→3D structures of Cas9) |
||
| Line 8: | Line 8: | ||
==3D structures of Cas9== | ==3D structures of Cas9== | ||
| - | * [[4un3], [[4un4]], and [[4un5]] - ''S. pyogenes'' Cas9 bound to sgRNA and target DNA | + | * [[4un3]], [[4un4]], and [[4un5]] - ''S. pyogenes'' Cas9 bound to sgRNA and target DNA |
* [[4oo8]] | * [[4oo8]] | ||
* [[4cmp]] | * [[4cmp]] | ||
| Line 16: | Line 16: | ||
*[[4oge]] | *[[4oge]] | ||
*[[4ogc]] - Mn<sup>2+</sup>-bound ''A.s naeslundii'' Cas9 | *[[4ogc]] - Mn<sup>2+</sup>-bound ''A.s naeslundii'' Cas9 | ||
| - | + | ||
==See Also== | ==See Also== | ||
[[HNH endonuclease]] <br/> | [[HNH endonuclease]] <br/> | ||
Revision as of 03:47, 28 November 2014
Cas9 is the RNA-guided DNA endonuclease used by the CRISPR-associated systems to generate double-strand DNA breaks in the invading DNA during an adaptive bacterial immune response.
It has been exploited for use in genome editing systems.
Articles in Proteopedia concerning Cas9 include:
- any?
Contents |
3D structures of Cas9
- 4un3, 4un4, and 4un5 - S. pyogenes Cas9 bound to sgRNA and target DNA
- 4oo8
- 4cmp
- 4cmq - Mn2+-bound S. pyogenes Cas9
Actinomyces naeslundii Cas9
See Also
References
Proteopedia Page Contributors and Editors (what is this?)
Wayne Decatur, Michal Harel, Karsten Theis, Joel L. Sussman, Ann Taylor, Thomas Gastineau
