Interleukin receptor
From Proteopedia
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**[[4dep]] – hIL1R1 extracellular domain + interleukin-1 β + + interleukin-1 accessory protein<br /> | **[[4dep]] – hIL1R1 extracellular domain + interleukin-1 β + + interleukin-1 accessory protein<br /> | ||
**[[4gaf]] – hIL1R1 extracellular domain + IL1β/IL1RA <br /> | **[[4gaf]] – hIL1R1 extracellular domain + IL1β/IL1RA <br /> | ||
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[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:33, 30 November 2014
Template:STRUCTURE 2b5i Interleukin receptors (ILR) are cytokine receptor which are classified into type I, type II and . ILR type I are cell surface receptors which recognize cytokines with four α-helical strands. ILR type II are similar to type I but lack the former’s signature sequence: WXSWS. Interleukin-1 receptor belongs to the ILR of immunoglobulin family. IL1R contains two types. Type I (IL1R1) binds interleukin-1 transmitting its inflammatory effect. Interleukin-1 receptor type II (IL1R2) suppresses interleukin-1 activity. Another suppressor of IL1R activity is the interleukin-1 receptor antagonist (IL1R1A).
3D structures of interleukin receptor
Updated on 30-November-2014 Interleukin receptor type I
Interleukin receptor type II
Interleukin receptor of immunoglobulin family
