Priyanka Basak/Sandbox

Helicobacter pylori (Hp) is a class I human pathogen that is involved in causing gastric ulcers and stomach cancers. Its two nickel dependent enzymes - Urease and NiFe-H2ase, provides it a unique ability to survive and colonize in acidic human stomach. Several accessory proteins play a crucial role in the maturation of these enzymes. UreE is specifically involved in the maturation of Urease, which catalyzes the conversion of urea to ammonia and carbamate thereby neutralizing its local acidic environment.

Function

UreE delivers Nickel to urease.

Disease

Relevance

Structural highlights

Headline text

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.