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Priyanka Basak/Sandbox
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==Introduction== | ==Introduction== | ||
<StructureSection load='3tj8' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='3tj8' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | ''Helicobacter pylori'' (''Hp'') is a class I human pathogen that is involved in causing gastric ulcers and stomach cancers. Its two nickel dependent enzymes - Urease and NiFe-H2ase, provides it a unique ability to survive and colonize in acidic human stomach. Several accessory proteins play a crucial role in the maturation of these enzymes. UreE is specifically involved in the maturation of Urease, which catalyzes the conversion of urea to ammonia and carbamate | + | ''Helicobacter pylori'' (''Hp'') is a class I human pathogen that is involved in causing gastric ulcers and stomach cancers. Its two nickel dependent enzymes - Urease and NiFe-H2ase, provides it a unique ability to survive and colonize in acidic human stomach. Several accessory proteins play a crucial role in the maturation of these enzymes. UreE is specifically involved in the maturation of Urease, which catalyzes the conversion of urea to ammonia and carbamate thereby neutralizing its local acidic environment. |
== Function == | == Function == | ||
UreE delivers Nickel to urease. | UreE delivers Nickel to urease. | ||
Revision as of 17:04, 2 December 2014
UreE: A Nickel Metallochaperone for Urease
Introduction
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References
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