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2yk7

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==STRUCTURE OF NEISSERIA LOS-SPECIFIC SIALYLTRANSFERASE (NST), IN COMPLEX WITH CMP-3F-NEU5AC.==
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==Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.==
<StructureSection load='2yk7' size='340' side='right' caption='[[2yk7]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='2yk7' size='340' side='right' caption='[[2yk7]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK7 OCA]. <br>
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<table><tr><td colspan='2'>[[2yk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimi Neimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YK7 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yk4|2yk4]], [[2yk5|2yk5]], [[2yk6|2yk6]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yk4|2yk4]], [[2yk5|2yk5]], [[2yk6|2yk6]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yk7 RCSB], [http://www.ebi.ac.uk/pdbsum/2yk7 PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yk7 RCSB], [http://www.ebi.ac.uk/pdbsum/2yk7 PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria meningitidis.,Lin LY, Rakic B, Chiu CP, Lameignere E, Wakarchuk WW, Withers SG, Strynadka NC J Biol Chem. 2011 Oct 28;286(43):37237-48. Epub 2011 Aug 31. PMID:21880735<ref>PMID:21880735</ref>
Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria meningitidis.,Lin LY, Rakic B, Chiu CP, Lameignere E, Wakarchuk WW, Withers SG, Strynadka NC J Biol Chem. 2011 Oct 28;286(43):37237-48. Epub 2011 Aug 31. PMID:21880735<ref>PMID:21880735</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Neisseria meningitidis serogroup b]]
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[[Category: Neimi]]
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[[Category: Chiu, C P.C.]]
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[[Category: Chiu, C P.C]]
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[[Category: Lameignere, E.]]
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[[Category: Lameignere, E]]
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[[Category: Lin, L Y.C.]]
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[[Category: Lin, L Y.C]]
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[[Category: Rakic, B.]]
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[[Category: Rakic, B]]
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[[Category: Strynadka, N C.J.]]
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[[Category: Strynadka, N C.J]]
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[[Category: Wakarchuk, W W.]]
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[[Category: Wakarchuk, W W]]
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[[Category: Withers, S G.]]
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[[Category: Withers, S G]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 07:50, 3 December 2014

Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.

2yk7, resolution 2.18Å

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