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Phosphoglycerate dehydrogenase
From Proteopedia
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==3D structures of phosphoglycerate dehydrogenase== | ==3D structures of phosphoglycerate dehydrogenase== | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *'''Phosphoglycerate dehydrogenase''' | |
| - | [[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> | + | **[[1ygy]], [[3dc2]] – MtPGDH – ''Mycobacterium tuberculosis''<br /> |
| - | [[3evt]] - PGDH – ''Lactobacillus plantarum''<br /> | + | **[[3evt]] - PGDH – ''Lactobacillus plantarum''<br /> |
| - | [[3gg9]] - PGDH – ''Ralstonia solanacearum''<br /> | + | **[[3gg9]] - PGDH – ''Ralstonia solanacearum''<br /> |
| - | [[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' | + | **[[3k5p]] - PGDH (mutant) – ''Brucella melitensis'' |
| - | + | *Phosphoglycerate dehydrogenase binary complex | |
| - | [[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> | + | **[[1sc6]], [[2p9c]], [[2p9e]], [[2p9g]] - EcPGDH (mutant) + NAD – ''Escherichia coli''<br /> |
| - | [[1yba]] - EcPGDH + NAD<br /> | + | **[[1yba]] - EcPGDH + NAD<br /> |
| - | [[1wwk]] - PGDH + NAD – ''Pyrococcus horikoshii''<br /> | + | **[[1wwk]] - PGDH + NAD – ''Pyrococcus horikoshii''<br /> |
| - | [[2g76]] - PGDH + NAD – human<br /> | + | **[[2g76]] - PGDH + NAD – human<br /> |
| - | [[2ekl]] - PGDH + NAD – ''Sulfolobus tokodaii''<br /> | + | **[[2ekl]] - PGDH + NAD – ''Sulfolobus tokodaii''<br /> |
| - | [[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate | + | **[[3ddn]] - MtPGDH + hydroxypyruvic acid phosphate |
| - | + | *Phosphoglycerate dehydrogenase ternary complex | |
| - | + | ||
| - | + | ||
| - | + | ||
| + | **[[1psd]] - EcPGDH + serine + NAD <br /> | ||
| + | **[[2pa3]] - EcPGDH (mutant) + serine + NAD | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:55, 3 December 2014
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Phosphoglycerate dehydrogenase (PGDH) catalyzes the conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate. This is the first step of serine biosynthesis. NAD is used as cofactor. In some cancer cells there is an elevation in PGDH level.
