Phosphoribosyltransferase

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{{#tree:id=OrganizedByTopic|openlevels=0|
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===Orotate PRT===
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*'''Orotate phosphoribosyltransferase'''
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[[1oro]] - EcOPRT – ''Escherichia coli''<br />
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**[[1oro]] - EcOPRT – ''Escherichia coli''<br />
-
[[1j7j]] - StOPRT – ''Salmonella typhimurium''<br />
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**[[1j7j]] - StOPRT – ''Salmonella typhimurium''<br />
-
[[2aee]] - OPRT – ''Streptococcus pyogenes''<br />
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**[[2aee]] - OPRT – ''Streptococcus pyogenes''<br />
-
[[3dez]] - OPRT – ''Streptococcus mutans''<br />
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**[[3dez]] - OPRT – ''Streptococcus mutans''<br />
-
[[2yzk]] – OPRT – ''Aeropyrum pernix''<br />
+
**[[2yzk]] – OPRT – ''Aeropyrum pernix''<br />
-
[[2pry]] - yOPRT – yeast<br />
+
**[[2pry]] - yOPRT – yeast<br />
-
[[3m3h]] - BaOPRT – ''Bacillus anthracis''<br />
+
**[[3m3h]] - BaOPRT – ''Bacillus anthracis''<br />
-
[[3mjd]] - OPRT – ''Francisella tularensis''<br />
+
**[[3mjd]] - OPRT – ''Francisella tularensis''<br />
-
[[3n2l]] - VcOPRT – ''Vibrio cholera''<br />
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**[[3n2l]] - VcOPRT – ''Vibrio cholera''<br />
-
[[3qw3]], [[3qw4]] - OPRT – ''Leishmania infantum''<br />
+
**[[3qw3]], [[3qw4]] - OPRT – ''Leishmania infantum''<br />
-
[[2p1z]] – OPRT – ''Corynebacterium diphtheriae''<br />
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**[[2p1z]] – OPRT – ''Corynebacterium diphtheriae''<br />
-
[[4fym]] - PfOPRT – ''Plasmodium falciparum''<br />
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**[[4fym]] - PfOPRT – ''Plasmodium falciparum''<br />
-
[[4ohc]] – OPRT – ''Burkholderia cenocepacia''<br />
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**[[4ohc]] – OPRT – ''Burkholderia cenocepacia''<br />
-
''Orotate PRT complex''
+
*Orotate phosphoribosyltransferase complex
-
[[1sto]]– StOPRT + OMP<br />
+
**[[1sto]]– StOPRT + OMP<br />
-
[[2prz]] - yOPRT + OMP<br />
+
**[[2prz]] - yOPRT + OMP<br />
-
[[2qcn]], [[2wns]], [[3l0k]], [[3l0n]], [[3mo7]] – hOPRT + UMP derivative<br />
+
**[[2qcn]], [[2wns]], [[3l0k]], [[3l0n]], [[3mo7]] – hOPRT + UMP derivative<br />
-
[[3mi2]] - hOPRT + pyrazofurin monophosphate<br />
+
**[[3mi2]] - hOPRT + pyrazofurin monophosphate<br />
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[[4hib]], [[4hkp]] - hOPRT + inhibitor<br />
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**[[4hib]], [[4hkp]] - hOPRT + inhibitor<br />
-
[[3osc]] - BaOPRT + PRPP<BR />
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**[[3osc]] - BaOPRT + PRPP<BR />
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[[1opr]], [[1lh0]] - StOPRT + orotate + PRPP<BR />
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**[[1opr]], [[1lh0]] - StOPRT + orotate + PRPP<BR />
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[[2ps1]] - yOPRT + orotate + PRPP<BR />
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**[[2ps1]] - yOPRT + orotate + PRPP<BR />
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===Hypoxanthine-guanine PRT===
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*'''Hypoxanthine-guanine phosphoribosyltransferase'''
-
[[1nul]], [[1grv]] - EcHGPRT <br />
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**[[1nul]], [[1grv]] - EcHGPRT <br />
-
[[1dbr]] - TgHGPRT – ''Toxoplasma gondii''<br />
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**[[1dbr]] - TgHGPRT – ''Toxoplasma gondii''<br />
-
[[1tc1]] - TcHGPRT – ''Trypanosoma cruzi''<br />
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**[[1tc1]] - TcHGPRT – ''Trypanosoma cruzi''<br />
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[[1r3u]] - TteHGPRT – ''Thermoanaerobacter tengongensis''<br />
+
**[[1r3u]] - TteHGPRT – ''Thermoanaerobacter tengongensis''<br />
-
[[2geb]] - TteHGPRT (mutant) <br />
+
**[[2geb]] - TteHGPRT (mutant) <br />
-
[[1vdm]] - PhHGPRT – ''Pyrococcus horikoshii''<br />
+
**[[1vdm]] - PhHGPRT – ''Pyrococcus horikoshii''<br />
-
[[1z7g]] - hHGPRT <br />
+
**[[1z7g]] - hHGPRT <br />
-
[[3h83]], [[3hvu]], [[3o7m]] - BaHGPRT<br />
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**[[3h83]], [[3hvu]], [[3o7m]] - BaHGPRT<br />
-
[[3acb]] - TtHGPRT – ''Thermus thermophilus''<br />
+
**[[3acb]] - TtHGPRT – ''Thermus thermophilus''<br />
-
[[3ohp]] - VcHGPRT <br />
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**[[3ohp]] - VcHGPRT <br />
-
[[4lyy]] – HGPRT – ''Shewanella pealeana''<br />
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**[[4lyy]] – HGPRT – ''Shewanella pealeana''<br />
-
''Hypoxanthine-guanine PRT binary complex''
+
*Hypoxanthine-guanine phosphoribosyltransferase binary complex
-
[[1a98]], [[1a97]] - EcHGPRT (mutant) + GMP<br />
+
**[[1a98]], [[1a97]] - EcHGPRT (mutant) + GMP<br />
-
[[1g9s]] - EcHGPRT + IMP<BR />
+
**[[1g9s]] - EcHGPRT + IMP<BR />
-
[[1g9t]] - EcHGPRT + GMP<br />
+
**[[1g9t]] - EcHGPRT + GMP<br />
-
[[1hmp]], [[2vfa]] - hHGPRT + GMP<br />
+
**[[1hmp]], [[2vfa]] - hHGPRT + GMP<br />
-
[[3gep]], [[3ggj]] - hHGPRT + guanine derivative<br />
+
**[[3gep]], [[3ggj]] - hHGPRT + guanine derivative<br />
-
[[3ggc]] - hHGPRT + hypoxanthine derivative<br />
+
**[[3ggc]] - hHGPRT + hypoxanthine derivative<br />
-
[[4ijq]] - hHGPRT + inhibitor<br />
+
**[[4ijq]] - hHGPRT + inhibitor<br />
-
[[4kn6]] - hHGPRT + antiviral agent<br />
+
**[[4kn6]] - hHGPRT + antiviral agent<br />
-
[[1hgx]] - HGPRT + GMP – ''Tritrichomonas foetus''<br />
+
**[[1hgx]] - HGPRT + GMP – ''Tritrichomonas foetus''<br />
-
[[1qk3]] - TgHGPRT + GMP<br />
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**[[1qk3]] - TgHGPRT + GMP<br />
-
[[1qk4]] - TgHGPRT + IMP<BR />
+
**[[1qk4]] - TgHGPRT + IMP<BR />
-
[[1p19]] - TcHGPRT + IMP<BR />
+
**[[1p19]] - TcHGPRT + IMP<BR />
-
[[1p17]] - TcHGPRT (mutant) + IMP<BR />
+
**[[1p17]] - TcHGPRT (mutant) + IMP<BR />
-
[[1yfz]] - TteHGPRT + IMP<BR />
+
**[[1yfz]] - TteHGPRT + IMP<BR />
-
[[1dqp]] - GiHGPRT + imucillin – ''Giardia intestinalis''<br />
+
**[[1dqp]] - GiHGPRT + imucillin – ''Giardia intestinalis''<br />
-
[[1pzm]] - LtHGPRT + GMP – ''Leishmania tarentolae''<br />
+
**[[1pzm]] - LtHGPRT + GMP – ''Leishmania tarentolae''<br />
-
[[1y0b]] - BsHGPRT + GTP – ''Bacillus subtilis''<br />
+
**[[1y0b]] - BsHGPRT + GTP – ''Bacillus subtilis''<br />
-
[[2fxv]] - BsHGPRT + GMP<br />
+
**[[2fxv]] - BsHGPRT + GMP<br />
-
[[3kb8]] - BaHGPRT + GMP<br />
+
**[[3kb8]] - BaHGPRT + GMP<br />
-
[[2jky]], [[2jkz]], [[2xbu]] - yHGPRT + GMP<br />
+
**[[2jky]], [[2jkz]], [[2xbu]] - yHGPRT + GMP<br />
-
[[3acc]] - TtHGPRT + GMP<br />
+
**[[3acc]] - TtHGPRT + GMP<br />
-
[[3acd]] - TtHGPRT + IMP<BR />
+
**[[3acd]] - TtHGPRT + IMP<BR />
-
[[1cjb]] - PfHGPRT + pyrophosphate <br />
+
**[[1cjb]] - PfHGPRT + pyrophosphate <br />
-
[[3ozf]] - PfHGPRT + hypoxanthine<br />
+
**[[3ozf]] - PfHGPRT + hypoxanthine<br />
-
[[3ozg]] - PfHGPRT + inhibitor<br />
+
**[[3ozg]] - PfHGPRT + inhibitor<br />
-
[[1dqn]] - GiHGPRT + transition state analog<br />
+
**[[1dqn]] - GiHGPRT + transition state analog<br />
-
[[1d6n]] - LdAPRT + AMP derivative<br />
+
**[[1d6n]] - LdAPRT + AMP derivative<br />
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''Hypoxanthine-guanine PRT ternary complex''
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*Hypoxanthine-guanine phosphoribosyltransferase ternary complex
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[[1a95]] - EcHGPRT + guanine + PRPP derivative<br />
+
**[[1a95]] - EcHGPRT + guanine + PRPP derivative<br />
-
[[1a96]] - EcHGPRT + xanthine + PRPP derivative<br />
+
**[[1a96]] - EcHGPRT + xanthine + PRPP derivative<br />
-
[[1bzy]] - hHGPRT + inhibitor + guanine derivative<br />
+
**[[1bzy]] - hHGPRT + inhibitor + guanine derivative<br />
-
[[1tc2]], [[1i0i]], [[1i0l]], [[1i13]], [[1i14]] – TcHGPRT + pyrimidine derivative + PRPP derivative<br />
+
**[[1tc2]], [[1i0i]], [[1i0l]], [[1i13]], [[1i14]] – TcHGPRT + pyrimidine derivative + PRPP derivative<br />
-
[[1p18]] - TcHGPRT (mutant) + pyrimidine derivative + PRPP<BR />
+
**[[1p18]] - TcHGPRT (mutant) + pyrimidine derivative + PRPP<BR />
-
[[1qk5]] - TgHGPRT (mutant) + XMP + pyrophosphate<br />
+
**[[1qk5]] - TgHGPRT (mutant) + XMP + pyrophosphate<br />
-
[[1fsg]] - TgHGPRT + guanine derivative + PRPP<BR />
+
**[[1fsg]] - TgHGPRT + guanine derivative + PRPP<BR />
-
[[1cjb]] - PfHGPRT + pyrophosphate + inhibitor<br />
+
**[[1cjb]] - PfHGPRT + pyrophosphate + inhibitor<br />
-
===Quinolinic acid PRT===
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*'''Quinolinic acid phosphoribosyltransferase'''
-
[[1o4u]] - TmQAPRT – ''Thermotoga maritima''<br />
+
**[[1o4u]] - TmQAPRT – ''Thermotoga maritima''<br />
-
[[2jbm]], [[3lar]], [[4kwv]] – hQAPRT<br />
+
**[[2jbm]], [[3lar]], [[4kwv]] – hQAPRT<br />
-
[[3c2e]] - yQAPRT <br />
+
**[[3c2e]] - yQAPRT <br />
-
[[1qpo]] – MtQAPRT – ''Mycobacterium tuberculosis'' <br />
+
**[[1qpo]] – MtQAPRT – ''Mycobacterium tuberculosis'' <br />
-
''Quinolinic acid PRT complex''
+
*Quinolinic acid phosphoribosyltransferase complex
-
[[1qap]] - StQAPRT + quinolinic acid<br />
+
**[[1qap]] - StQAPRT + quinolinic acid<br />
-
[[1qpr]] - MtQAPRT + PRPP derivative <br />
+
**[[1qpr]] - MtQAPRT + PRPP derivative <br />
-
[[1qpn]] – MtQAPRT + nicotinate mononucleotide <br />
+
**[[1qpn]] – MtQAPRT + nicotinate mononucleotide <br />
-
[[1qpq]] - MtQAPRT + quinolinic acid<br />
+
**[[1qpq]] - MtQAPRT + quinolinic acid<br />
-
[[3c2o]] - yQAPRT + quinolinic acid<br />
+
**[[3c2o]] - yQAPRT + quinolinic acid<br />
-
[[3c2f]] - yQAPRT + PRPP<BR />
+
**[[3c2f]] - yQAPRT + PRPP<BR />
-
[[3c2r]] - yQAPRT + inhibitor<br />
+
**[[3c2r]] - yQAPRT + inhibitor<br />
-
[[3c2v]] - yQAPRT + inhibitor + PRPP<BR />
+
**[[3c2v]] - yQAPRT + inhibitor + PRPP<BR />
-
[[4i9a]] – QAPRT + nicotinate mononucleotide – pig<br />
+
**[[4i9a]] – QAPRT + nicotinate mononucleotide – pig<br />
-
[[2b7n]] – HpQAPRT + quinolinic acid – ''Helicobacter pylori''<br />
+
**[[2b7n]] – HpQAPRT + quinolinic acid – ''Helicobacter pylori''<br />
-
[[4kww]] – hQAPRT + phthalate <br />
+
**[[4kww]] – hQAPRT + phthalate <br />
-
[[2b7p]] – HpQAPRT + phthalate <br />
+
**[[2b7p]] – HpQAPRT + phthalate <br />
-
[[2b7q]] – HpQAPRT + nicotinate mononucleotide <br />
+
**[[2b7q]] – HpQAPRT + nicotinate mononucleotide <br />
-
===Uracil PRT===
+
*'''Uracil phosphoribosyltransferase'''
-
[[1w30]] - MtUPRT <br />
+
**[[1w30]] - MtUPRT <br />
-
[[1bd3]] - TgUPRT (mutant) <br />
+
**[[1bd3]] - TgUPRT (mutant) <br />
-
[[1v9s]] - TtUPRT <br />
+
**[[1v9s]] - TtUPRT <br />
-
[[2e55]] - UPRT – ''Aquifex aeolicus'' <br />
+
**[[2e55]] - UPRT – ''Aquifex aeolicus'' <br />
-
[[2ehj]] - EcUPRT <br />
+
**[[2ehj]] - EcUPRT <br />
-
[[3dmp]] - UPRT – ''Burkholderia pseudomallei''
+
**[[3dmp]] - UPRT – ''Burkholderia pseudomallei''
-
''Uracil PRT complex''
+
*Uracil phosphoribosyltransferase complex
-
[[1upu]] - TgUPRT (mutant) + UMP<br />
+
**[[1upu]] - TgUPRT (mutant) + UMP<br />
-
[[1o5o]] - TmUPRT + UMP<br />
+
**[[1o5o]] - TmUPRT + UMP<br />
-
[[1jlr]] - TgUPRT (mutant) + GTP<br />
+
**[[1jlr]] - TgUPRT (mutant) + GTP<br />
-
[[1bd4]] - TgUPRT (mutant) + uracil<br />
+
**[[1bd4]] - TgUPRT (mutant) + uracil<br />
-
[[1upf]] - TgUPRT (mutant) + fluorouracil<br />
+
**[[1upf]] - TgUPRT (mutant) + fluorouracil<br />
-
[[1i5e]], [[2igb]] - UPRT + UMP – ''Bacillus caldolyticus''<br />
+
**[[1i5e]], [[2igb]] - UPRT + UMP – ''Bacillus caldolyticus''<br />
-
[[1jls]] - TgUPRT (mutant) + uracil + PRPP<BR />
+
**[[1jls]] - TgUPRT (mutant) + uracil + PRPP<BR />
-
[[1vst]], [[3g6w]] - SsUPRT + GTP + PRPP – ''Sulfolobus solfataricus''
+
**[[1vst]], [[3g6w]] - SsUPRT + GTP + PRPP – ''Sulfolobus solfataricus''
-
===Adenine PRT===
+
*'''Adenine phosphoribosyltransferase'''
-
[[1qcc]], [[1qcd]] - LdAPRT – ''Leishmania donovani''<br />
+
**[[1qcc]], [[1qcd]] - LdAPRT – ''Leishmania donovani''<br />
-
[[1g2p]], [[1g2q]] – yAPRT <br />
+
**[[1g2p]], [[1g2q]] – yAPRT <br />
-
[[2dy0]] - EcAPRT <br />
+
**[[2dy0]] - EcAPRT <br />
-
[[4lza]] – APRT – ''Thermoanaerobacter pseudethanolicus''<br />
+
**[[4lza]] – APRT – ''Thermoanaerobacter pseudethanolicus''<br />
-
[[4m0k]] – APRT – ''Rhodothermus marinus''<br />
+
**[[4m0k]] – APRT – ''Rhodothermus marinus''<br />
-
[[4mb6]] – APRT – ''Yersinia pseudotuberculosis''<br />
+
**[[4mb6]] – APRT – ''Yersinia pseudotuberculosis''<br />
-
''Adenine PRT complex''
+
*Adenine phosphoribosyltransferase complex
-
[[1qb7]] - LdAPRT + adenine<br />
+
**[[1qb7]] - LdAPRT + adenine<br />
-
[[1qb8]] - LdAPRT + AMP<br />
+
**[[1qb8]] - LdAPRT + AMP<br />
-
[[1ore]], [[1zn8]], [[1zn9]] - hAPRT + AMP<br />
+
**[[1ore]], [[1zn8]], [[1zn9]] - hAPRT + AMP<br />
-
[[1mzv]] - LtAPRT + AMP<br />
+
**[[1mzv]] - LtAPRT + AMP<br />
-
[[1zn7]] - hHGPRT + adenine + PRPP<BR />
+
**[[1zn7]] - hHGPRT + adenine + PRPP<BR />
-
[[1l1q]] - GiAPRT + adenine derivative<br />
+
**[[1l1q]] - GiAPRT + adenine derivative<br />
-
[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR />
+
**[[1l1r]] - GiAPRT + adenine derivative + PRPP<BR />
-
===Nicotinate mononucleotide:5, 6-dimethylbenzimidazole PRT===
+
*'''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase'''
-
[[1l4b]] – SeNN:DBI PRT – ''Salmonella enterica''<br />
+
**[[1l4b]] – SeNN:DBI PRT – ''Salmonella enterica''<br />
-
[[4kqh]] - SeNN:DBI PRT (mutant)<br />
+
**[[4kqh]] - SeNN:DBI PRT (mutant)<br />
-
[[1wx1]] – TtNN:DBI PRT <br />
+
**[[1wx1]] – TtNN:DBI PRT <br />
-
[[3u4g]] – PhNN:DBI PRT
+
**[[3u4g]] – PhNN:DBI PRT
-
''Nicotinate mononucleotide:5, 6-dimethylbenzimidazole PRT complex''
+
*Nicotinate mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase complex
-
[[1jh8]], [[4kpf]] – SeNN:DBI PRT + adenine<br />
+
**[[1jh8]], [[4kpf]] – SeNN:DBI PRT + adenine<br />
-
[[1l4e]], [[1l4f]], [[1l4g]], [[1l4h]], [[1l4k]], [[1l4l]], [[1l4m]], [[1l4n]], [[1l5f]], [[1l5k]], [[1l5l]], [[1l5m]], [[1l5n]], [[1l5o]] - SeNN:DBI PRT + product-aldimine complex<br />
+
**[[1l4e]], [[1l4f]], [[1l4g]], [[1l4h]], [[1l4k]], [[1l4l]], [[1l4m]], [[1l4n]], [[1l5f]], [[1l5k]], [[1l5l]], [[1l5m]], [[1l5n]], [[1l5o]] - SeNN:DBI PRT + product-aldimine complex<br />
-
[[1jha]] – SeNN:DBI PRT + AMP + nicotinate<br />
+
**[[1jha]] – SeNN:DBI PRT + AMP + nicotinate<br />
-
[[4kqi]] - SeNN:DBI PRT (mutant) + nicotinate + α-ribazole phosphate<br />
+
**[[4kqi]] - SeNN:DBI PRT (mutant) + nicotinate + α-ribazole phosphate<br />
-
[[1jhm]] – SeNN:DBI PRT + benzimidazole<br />
+
**[[1jhm]] – SeNN:DBI PRT + benzimidazole<br />
-
[[1jho]] – SeNN:DBI PRT + NaMN + benzimidazole<br />
+
**[[1jho]] – SeNN:DBI PRT + NaMN + benzimidazole<br />
-
[[1jhp]] – SeNN:DBI PRT + benzimidazole derivative<br />
+
**[[1jhp]] – SeNN:DBI PRT + benzimidazole derivative<br />
-
[[1jhq]] - SeNN:DBI PRT + NaMN + benzimidazole derivative<br />
+
**[[1jhq]] - SeNN:DBI PRT + NaMN + benzimidazole derivative<br />
-
[[1jhr]] - SeNN:DBI PRT + NaMN + hydroxypurine<br />
+
**[[1jhr]] - SeNN:DBI PRT + NaMN + hydroxypurine<br />
-
[[1jhu]] - SeNN:DBI PRT + cresol<br />
+
**[[1jhu]] - SeNN:DBI PRT + cresol<br />
-
[[4kqk]] - SeNN:DBI PRT (mutant) + cresol<br />
+
**[[4kqk]] - SeNN:DBI PRT (mutant) + cresol<br />
-
[[1jhv]] - SeNN:DBI PRT + nicotinate + cresol<br />
+
**[[1jhv]] - SeNN:DBI PRT + nicotinate + cresol<br />
-
[[1jhx]] - SeNN:DBI PRT + phenol<br />
+
**[[1jhx]] - SeNN:DBI PRT + phenol<br />
-
[[1jhy]] - SeNN:DBI PRT + phenol + nicotinate<br />
+
**[[1jhy]] - SeNN:DBI PRT + phenol + nicotinate<br />
-
[[4kqj]] - SeNN:DBI PRT (mutant) + NaMN + cresol<br />
+
**[[4kqj]] - SeNN:DBI PRT (mutant) + NaMN + cresol<br />
-
[[4kqg]] - SeNN:DBI PRT (mutant) + cobamide<br />
+
**[[4kqg]] - SeNN:DBI PRT (mutant) + cobamide<br />
-
===Anthranilate PRT===
+
*'''Anthranilate phosphoribosyltransferase'''
-
[[1o17]] - SsANPRT <br />
+
**[[1o17]] - SsANPRT <br />
-
[[1khd]] – PcANPRT – ''Pectobacterium carotovorum''<br />
+
**[[1khd]] – PcANPRT – ''Pectobacterium carotovorum''<br />
-
[[1v8g]], [[2elc]] - TtANPRT <br />
+
**[[1v8g]], [[2elc]] - TtANPRT <br />
-
[[1vqu]] - ANPRT – Nostoc<br />
+
**[[1vqu]] - ANPRT – Nostoc<br />
-
[[3qr9]] – MtANPRT<br />
+
**[[3qr9]] – MtANPRT<br />
-
[[4hkm]] - ANPRT – ''Xanthomonas campestris''<br />
+
**[[4hkm]] - ANPRT – ''Xanthomonas campestris''<br />
-
[[4gtn]] – ANPRT – ''Acinetobacter''<br />
+
**[[4gtn]] – ANPRT – ''Acinetobacter''<br />
-
''Anthranilate PRT complex''
+
*Anthranilate phosphoribosyltransferase complex
-
[[1kgz]] - PcANPRT + PRPP<BR />
+
**[[1kgz]] - PcANPRT + PRPP<BR />
-
[[1zvw]] - MtANPRT + PRPP<BR />
+
**[[1zvw]] - MtANPRT + PRPP<BR />
-
[[4ij1]] - MtANPRT + anthranilate derivative <br />
+
**[[4ij1]] - MtANPRT + anthranilate derivative <br />
-
[[1zxy]] - SsANPRT + PRPP<BR />
+
**[[1zxy]] - SsANPRT + PRPP<BR />
-
[[3gbr]] - SsANPRT (mutant) + PRPP<BR />
+
**[[3gbr]] - SsANPRT (mutant) + PRPP<BR />
-
[[1gxb]] - SsANPRT + pyrophosphate<br />
+
**[[1gxb]] - SsANPRT + pyrophosphate<br />
-
[[2gvq]] - SsANPRT + anthranilate<br />
+
**[[2gvq]] - SsANPRT + anthranilate<br />
-
[[3qqs]], [[3qs8]], [[3qsa]], [[3r6c]], [[3r88]], [[3twp]], [[3uu1]] - MtANPRT + inhibitor + PRPP<BR />
+
**[[3qqs]], [[3qs8]], [[3qsa]], [[3r6c]], [[3r88]], [[3twp]], [[3uu1]] - MtANPRT + inhibitor + PRPP<BR />
-
[[1zyk]] - SsANPRT + anthranilate + PRPP<BR />
+
**[[1zyk]] - SsANPRT + anthranilate + PRPP<BR />
-
[[4giu]], [[4gkm]]- PfANPRT + anthranilate derivative + PRPP<br />
+
**[[4giu]], [[4gkm]]- PfANPRT + anthranilate derivative + PRPP<br />
-
===ATP PRT===
+
*'''ATP phosphoribosyltransferase''' See [[ATP Phosphoribosyl Transferase]]
-
See [[ATP Phosphoribosyl Transferase]]
+
*'''Nicotinate phosphoribosyltransferase'''
-
===Nicotinate PRT===
+
**[[1vlp]] - yNIPRT <br />
 +
**[[1ybe]] - NIPRT – ''Agrobacterium tumefaciens''<br />
 +
**[[1yir]] - NIPRT – ''Pseudomonas aeruginosa''<br />
 +
**[[1ytd]], [[2i1o]] - TaNIPRT – ''Thermoplasma acidophilum''<br />
 +
**[[2bpq]] - MtNIPRT <br />
 +
**[[2im5]] - NIPRT – ''Porphyromonas gingivalis''<br />
 +
**[[3os4]] - NIPRT – ''Yersinia pestis''<br />
 +
**[[4hl7]] - VcNIPRT
-
[[1vlp]] - yNIPRT <br />
+
*Nicotinate phosphoribosyltransferase complex
-
[[1ybe]] - NIPRT – ''Agrobacterium tumefaciens''<br />
+
-
[[1yir]] - NIPRT – ''Pseudomonas aeruginosa''<br />
+
-
[[1ytd]], [[2i1o]] - TaNIPRT – ''Thermoplasma acidophilum''<br />
+
-
[[2bpq]] - MtNIPRT <br />
+
-
[[2im5]] - NIPRT – ''Porphyromonas gingivalis''<br />
+
-
[[3os4]] - NIPRT – ''Yersinia pestis''<br />
+
-
[[4hl7]] - VcNIPRT
+
-
''Nicotinate PRT complex''
+
**[[1yte]] - TaNIPRT + PRPP<BR />
 +
**[[1ytk]] - TaNIPRT + NAMN<br />
 +
**[[4mzy]] – NIPRT + malonate + Pi<br />
-
[[1yte]] - TaNIPRT + PRPP<BR />
+
*'''Nicotinamide phosphoribosyltransferase'''
-
[[1ytk]] - TaNIPRT + NAMN<br />
+
-
[[4mzy]] – NIPRT + malonate + Pi<br />
+
-
===Nicotinamide PRT===
+
**[[2gvl]] - mNMPRT – mouse<br />
 +
**[[2g95]] - NMPRT - rat<br />
 +
**[[2h3b]] – mNMPRT (mutant) <br />
 +
**[[2e5b]] – hNMPRT
-
[[2gvl]] - mNMPRT – mouse<br />
+
*Nicotinamide phosphoribosyltransferase complex
-
[[2g95]] - NMPRT - rat<br />
+
-
[[2h3b]] – mNMPRT (mutant) <br />
+
-
[[2e5b]] – hNMPRT
+
-
 
+
-
''Nicotinamide PRT complex''
+
-
[[2h3d]] - mNMPRT + NMN<BR />
+
**[[2h3d]] - mNMPRT + NMN<BR />
-
[[2gvg]] - hNMPRT + NMN<BR />
+
**[[2gvg]] - hNMPRT + NMN<BR />
-
[[2g96]] - rNMPRT + NMN<BR />
+
**[[2g96]] - rNMPRT + NMN<BR />
-
[[2g97]], [[3g8e]] - rNMPRT + FK-866<br />
+
**[[2g97]], [[3g8e]] - rNMPRT + FK-866<br />
-
[[2gvj]] - hNMPRT + FK-866<br />
+
**[[2gvj]] - hNMPRT + FK-866<br />
-
[[2e5c]] - hNMPRT + PRPP<BR />
+
**[[2e5c]] - hNMPRT + PRPP<BR />
-
[[2e5d]] - hNMPRT + nicotinamide<br />
+
**[[2e5d]] - hNMPRT + nicotinamide<br />
-
[[3dgr]] - hNMPRT + ADP analog<br />
+
**[[3dgr]] - hNMPRT + ADP analog<br />
-
[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]] - hNMPRT + inhibitor<br />
+
**[[4jnm]], [[4jr5]], [[4kfn]], [[4kfo]], [[4kfp]], [[4lts]], [[4lv9]], [[4lva]], [[4lvb]], [[4lvd]], [[4lvf]], [[4lvg]], [[4lww]], [[4m6p]], [[4m6q]], [[4n9b]], [[4n9c]], [[4n9d]], [[4n9e]] - hNMPRT + inhibitor<br />
-
[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR />
+
**[[3dhd]], [[3dhf]] - hNMPRT + pyrophosphate + NMN<BR />
-
[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR />
+
**[[3dkj]], [[3dkl]] - hNMPRT + benzamide + PRPP<BR />
-
 
+
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:47, 3 December 2014

Template:STRUCTURE 3l0k

Phosphoribosyltransferase (PRT) are transferases which belong to several classes:
1. Hypoxanthine-guanine PRT (HGPRT). HGPRT is part of the purine biosynthesis and catalyzes the formation of GMP from guanine, xanthosine monophosphate from xanthosine and of inosine monophosphate from hypoxanthine.
2. Orotate PRT (OPRT). OPRT is part of the pyrimidine biosynthesis and catalyzes the formation of orotidine 5’-monophosphate (OMP) from orotate and phosphoribosyl pyrophosphate (PRPP).
3. Quinolinic acid PRT (QAPRT ). QAPRT is a degrading enzyme found in the brain.
4. Uracil PRT (UPRT). UPRT catalyzes the formation of UMP from uracil and PRPP. Adenine PRT (APRT). APRT catalyzes the formation of AMP from adenine and PRPP.
5. Nicotinate nucleotide dimethylbenzimidazole PRT (NN:DBI PRT). NN:DBI PRT is part of riboflavin, porphyrin and chlorophyll biosynthesis.
6. Anthranilate PRT (ANPRT). ANPRT participates in phenylalanine, tyrosine and tryptophan biosynthesis and catalyzes the formation of anthraniline from phosphoribosyl anthranilate.
7. ATP PRT participates in histidine biosynthesis and catalyzes the formation of ATP from phosphoribosyl ATP and diphosphate.
8. Nicotinate PRT (NIPRT). NIPRT catalyzes the formation of nicotinate from nicotinate ribonucleotide and diphosphate.
9. Nicotinamide PRT (NMPRT). NMPRT catalyzes the formation of nicotinamide from nicotinamide ribonucleotide (NMN) and diphosphate.

3D structures of phosphoribosyltransferase

Updated on 03-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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