4uwj

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'''Unreleased structure'''
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==Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a capped pyrazole sulphonamide ligand==
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<StructureSection load='4uwj' size='340' side='right' caption='[[4uwj]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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The entry 4uwj is ON HOLD until Paper Publication
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uwj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UWJ FirstGlance]. <br>
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Authors: Robinson, D.A., Brand, S., Norcross, N.R., Thompson, S., Harrison, J.R., Smith, V.C., Torrie, L.S., McElroy, S.P., Hallyburton, I., Norval, S., Stojanovski, L., Simeons, F.R.C., Frearson, J.A., Brenk, R., Fairlamb, A.H., Ferguson, M.A.J., Wyatt, P.G., Gilbert, I.H., Read, K.D.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7L5:2,6-DICHLORO-N-(DIFLUOROMETHYL)-4-[3-(PIPERIDIN-4-YL)PROPYL]-N-(1,3,5-TRIMETHYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE'>7L5</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uwi|4uwi]]</td></tr>
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Description: Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a capped pyrazole sulphonamide ligand
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uwj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uwj RCSB], [http://www.ebi.ac.uk/pdbsum/4uwj PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
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[[Category: Glycylpeptide N-tetradecanoyltransferase]]
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[[Category: Brand, S]]
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[[Category: Brenk, R]]
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[[Category: Fairlamb, A H]]
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[[Category: Ferguson, M A.J]]
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[[Category: Frearson, J A]]
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[[Category: Gilbert, I H]]
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[[Category: Hallyburton, I]]
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[[Category: Harrison, J R]]
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[[Category: McElroy, S P]]
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[[Category: Norcross, N R]]
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[[Category: Norval, S]]
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[[Category: Read, K D]]
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[[Category: Robinson, D A]]
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[[Category: Simeons, F R.C]]
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[[Category: Smith, V C]]
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[[Category: Stojanovski, L]]
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[[Category: Thompson, S]]
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[[Category: Torrie, L S]]
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[[Category: Wyatt, P G]]
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[[Category: Drug discovery]]
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[[Category: Transferase]]

Revision as of 09:48, 3 December 2014

Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a capped pyrazole sulphonamide ligand

4uwj, resolution 1.70Å

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